4WI6
 
 | | Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation N434A | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | | 著者 | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | | 登録日 | 2014-09-25 | | 公開日 | 2015-09-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice
To Be Published
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6N52
 | | Metabotropic Glutamate Receptor 5 Apo Form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5 | | 著者 | Koehl, A, Hu, H, Feng, D, Sun, B, Weis, W.I, Skiniotis, G.S, Mathiesen, J.M, Kobilka, B.K. | | 登録日 | 2018-11-20 | | 公開日 | 2019-01-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural insights into the activation of metabotropic glutamate receptors.
Nature, 566, 2019
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6JER
 | | Apo crystal structure of class I type a peptide deformylase from Acinetobacter baumannii | | 分子名称: | Peptide deformylase, ZINC ION | | 著者 | Ho, T.H, Lee, I.H, Kang, L.W. | | 登録日 | 2019-02-07 | | 公開日 | 2020-02-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Expression, crystallization, and preliminary X-ray crystallographic analysis of peptide deformylase from Acinetobacter baumanii
Biodesign, 5, 2017
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4IJJ
 | | Structure of transcription factor DksA2 from Pseudomonas aeruginosa | | 分子名称: | Putative C4-type zinc finger protein, DksA/TraR family, SULFATE ION | | 著者 | Biswas, T, Furman, R, Artsimovitch, I, Tsodikov, O.V. | | 登録日 | 2012-12-21 | | 公開日 | 2013-02-27 | | 最終更新日 | 2013-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | DksA2, a zinc-independent structural analog of the transcription factor DksA.
Febs Lett., 587, 2013
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6HHJ
 | | Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor 24b | | 分子名称: | RAC-alpha serine/threonine-protein kinase, ~{N}-[1-methyl-2-oxidanylidene-3-[1-[[4-(5-oxidanylidene-3-phenyl-6~{H}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]benzimidazol-5-yl]propanamide | | 著者 | Landel, I, Weisner, J, Mueller, M.P, Scheinpflug, R, Rauh, D. | | 登録日 | 2018-08-28 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt.
Chem Sci, 10, 2019
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5KG9
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5KHK
 | | HCN2 CNBD in complex with 2-aminopurine riboside-3', 5'-cyclic monophosphate (2-NH2-cPuMP) | | 分子名称: | 2-Aminopurine riboside-3',5'-cyclic monophosphate, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | | 著者 | Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A. | | 登録日 | 2016-06-14 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
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5KDN
 | | ZmpB metallopeptidase from Clostridium perfringens | | 分子名称: | 1,2-ETHANEDIOL, F5/8 type C domain protein, ZINC ION | | 著者 | Noach, I, Ficko-Blean, E, Stuart, C, Boraston, A.B. | | 登録日 | 2016-06-08 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Recognition of protein-linked glycans as a determinant of peptidase activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4WUK
 | | Crystal structure of apo CH65 Fab | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CH65 heavy chain, CH65 light chain | | 著者 | Lee, P.S, Wilson, I.A. | | 登録日 | 2014-11-01 | | 公開日 | 2015-02-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of the apo anti-influenza CH65 Fab.
Acta Crystallogr.,Sect.F, 71, 2015
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5KHJ
 | | HCN2 CNBD in complex with uridine-3', 5'-cyclic monophosphate (cUMP) | | 分子名称: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, Uridine-3',5'-cyclic monophosphate | | 著者 | Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A. | | 登録日 | 2016-06-14 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
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6MSI
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6MWM
 | | Bat coronavirus HKU4 SUD-C | | 分子名称: | Non-structural protein 3 | | 著者 | Staup, A.J, De Silva, I.U, Catt, J.T, Tan, X, Hammond, R.G, Johnson, M.A. | | 登録日 | 2018-10-29 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the SARS-Unique Domain C From the Bat Coronavirus HKU4.
Nat Prod Commun, 14, 2019
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6MK5
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4IGW
 | | Crystal structure of kirola (Act d 11) in P6122 space group | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Kirola, ... | | 著者 | Chruszcz, M, Ciardiello, M.A, Giangrieco, I, Osinski, T, Minor, W. | | 登録日 | 2012-12-18 | | 公開日 | 2013-09-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural and bioinformatic analysis of the kiwifruit allergen Act d 11, a member of the family of ripening-related proteins.
Mol.Immunol., 56, 2013
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5JZ6
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4CRC
 | | Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design | | 分子名称: | (2S)-2-[[(E)-3-[5-chloranyl-2-(1,2,3,4-tetrazol-1-yl)phenyl]prop-2-enoyl]amino]-3-phenyl-N-[4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]propanamide, COAGULATION FACTOR XI, SULFATE ION | | 著者 | Sandmark, J, Oster, L, Fjellstrom, O, Akkaya, S, Beisel, H.G, Eriksson, P.O, Erixon, K, Gustafsson, D, Jurva, U, Kang, D, Karis, D, Knecht, W, Nerme, V, Nilsson, I, Olsson, T, Redzic, A, Roth, R, Tigerstrom, A. | | 登録日 | 2014-02-26 | | 公開日 | 2015-02-11 | | 最終更新日 | 2015-08-19 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Creating Novel Activated Factor Xi Inhibitors Through Fragment Based Lead Generation and Structure Aided Drug Design.
Plos One, 10, 2015
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5JZT
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5JS1
 | | Human Argonaute2 Bound to an siRNA | | 分子名称: | MAGNESIUM ION, PHENOL, Protein argonaute-2, ... | | 著者 | Schirle, N.T, MacRae, I.J. | | 登録日 | 2016-05-07 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide.
J.Am.Chem.Soc., 138, 2016
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4WJ4
 | | Crystal structure of non-discriminating aspartyl-tRNA synthetase from Pseudomonas aeruginosa complexed with tRNA(Asn) and aspartic acid | | 分子名称: | 76mer-tRNA, ASPARTIC ACID, Aspartate--tRNA(Asp/Asn) ligase | | 著者 | Suzuki, T, Nakamura, A, Kato, K, Tanaka, I, Yao, M. | | 登録日 | 2014-09-29 | | 公開日 | 2014-12-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.294 Å) | | 主引用文献 | Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis
Proc.Natl.Acad.Sci.USA, 112, 2015
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4CN4
 | | GlgE isoform 1 from Streptomyces coelicolor E423A mutant with 2-deoxy- 2-fluoro-beta-maltosyl modification | | 分子名称: | ALPHA-1,4-GLUCAN:MALTOSE-1-PHOSPHATE MALTOSYLTRANSFERASE 1, alpha-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-beta-D-glucopyranose | | 著者 | Syson, K, Stevenson, C.E.M, Rashid, A.M, Saalbach, G, Tang, M, Tuukanen, A, Svergun, D.I, Withers, S.G, Lawson, D.M, Bornemann, S. | | 登録日 | 2014-01-21 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Insight Into How Streptomyces Coelicolor Maltosyl Transferase Glge Binds Alpha-Maltose 1-Phosphate and Forms a Maltosyl-Enzyme Intermediate.
Biochemistry, 53, 2014
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6HQI
 | | holo-form of polyphenol oxidase from Solanum lycopersicum | | 分子名称: | COPPER (II) ION, OXYGEN ATOM, Polyphenol oxidase A, ... | | 著者 | Kampatsikas, I, Bijelic, A, Rompel, A. | | 登録日 | 2018-09-25 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Biochemical and structural characterization of tomato polyphenol oxidases provide novel insights into their substrate specificity.
Sci Rep, 9, 2019
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6HR0
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6RAE
 | | Structural analysis of the Salmonella type III secretion system ATPase InvC | | 分子名称: | CHLORIDE ION, GLYCEROL, Secretory apparatus ATP synthase (Associated with virulence) | | 著者 | Bernal, I, Roemermann, J, Flacht, L, Lunelli, M, Uetrecht, C, Kolbe, M. | | 登録日 | 2019-04-05 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.049 Å) | | 主引用文献 | Structural analysis of ligand-bound states of the Salmonella type III secretion system ATPase InvC.
Protein Sci., 28, 2019
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4CRA
 | | Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design | | 分子名称: | COAGULATION FACTOR XI, GLYCEROL, N-[(1S)-2-[(2-amino-5-quinolyl)methylamino]-1-benzyl-2-oxo-ethyl]-4-hydroxy-2-oxo-1H-quinoline-6-carboxamide, ... | | 著者 | Sandmark, J, Oster, L, Fjellstrom, O, Akkaya, S, Beisel, H.G, Eriksson, P.O, Erixon, K, Gustafsson, D, Jurva, U, Kang, D, Karis, D, Knecht, W, Nerme, V, Nilsson, I, Olsson, T, Redzic, A, Roth, R, Tigerstrom, A. | | 登録日 | 2014-02-26 | | 公開日 | 2015-02-11 | | 最終更新日 | 2018-04-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Creating Novel Activated Factor Xi Inhibitors Through Fragment Based Lead Generation and Structure Aided Drug Design.
Plos One, 10, 2015
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4CRD
 | | Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design | | 分子名称: | COAGULATION FACTOR XI, Methyl N-[4-[5-chloro-2-[[3-[5-chloro-2-(tetrazol-1-yl)phenyl]propanoylamino]methyl]-1H-imidazol-4-yl]phenyl]carbamate, SULFATE ION | | 著者 | Sandmark, J, Oster, L, Fjellstrom, O, Akkaya, S, Beisel, H.G, Eriksson, P.O, Erixon, K, Gustafsson, D, Jurva, U, Kang, D, Karis, D, Knecht, W, Nerme, V, Nilsson, I, Olsson, T, Redzic, A, Roth, R, Tigerstrom, A. | | 登録日 | 2014-02-26 | | 公開日 | 2015-02-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Creating Novel Activated Factor Xi Inhibitors Through Fragment Based Lead Generation and Structure Aided Drug Design.
Plos One, 10, 2015
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