7NHT
 
 | | Akirin2 bound human proteasome | | 分子名称: | Akirin-2, POTASSIUM ION, Proteasome subunit alpha type-1, ... | | 著者 | Singh, K, Brunner, H, Grishkovskaya, I, de Almeida, M, Hinterndorfer, M, Zuber, J, Haselbach, D. | | 登録日 | 2021-02-11 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
Nature, 599, 2021
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2NPI
 | | Clp1-ATP-Pcf11 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein CLP1, ... | | 著者 | Noble, C.G, Beuth, B, Taylor, I.A. | | 登録日 | 2006-10-27 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
Nucleic Acids Res., 35, 2007
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5AGQ
 | | Solution structure of the TAM domain of human TIP5 BAZ2A involved in epigenetic regulation of rRNA genes | | 分子名称: | BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A | | 著者 | Anosova, I, Melnik, S, Tripsianes, K, Kateb, F, Grummt, I, Sattler, M. | | 登録日 | 2015-02-03 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Novel RNA Binding Surface of the Tam Domain of Tip5/Baz2A Mediates Epigenetic Regulation of Rrna Genes.
Nucleic Acids Res., 43, 2015
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1RIS
 | | CRYSTAL STRUCTURE OF THE RIBOSOMAL PROTEIN S6 FROM THERMUS THERMOPHILUS | | 分子名称: | RIBOSOMAL PROTEIN S6 | | 著者 | Lindahl, M, Svensson, L.A, Liljas, A, Sedelnikova, S.E, Eliseikina, I.A, Fomenkova, N.P, Nevskaya, N, Nikonov, S.V, Garber, M.B, Muranova, T.A, Rykonova, A.I, Amons, R. | | 登録日 | 1994-05-31 | | 公開日 | 1994-09-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the ribosomal protein S6 from Thermus thermophilus.
EMBO J., 13, 1994
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4PXK
 | | Crystal structure of Haloarcula marismortui bacteriorhodopsin I D94N mutant | | 分子名称: | Bacteriorhodopsin, EICOSANE, RETINAL, ... | | 著者 | Shevchenko, V, Gushchin, I, Polovinkin, V, Gordeliy, V. | | 登録日 | 2014-03-24 | | 公開日 | 2014-12-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of Escherichia coli-Expressed Haloarcula marismortui Bacteriorhodopsin I in the Trimeric Form.
Plos One, 9, 2014
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7BPY
 | | X-ray structure of human PPARalpha ligand binding domain-clofibric acid-SRC1 coactivator peptide co-crystals obtained by delipidation and co-crystallization | | 分子名称: | 15-meric peptide from Nuclear receptor coactivator 1, 2-(4-chloranylphenoxy)-2-methyl-propanoic acid, Peroxisome proliferator-activated receptor alpha | | 著者 | Kamata, S, Ishikawa, R, Akahane, M, Oyama, T, Ishii, I. | | 登録日 | 2020-03-23 | | 公開日 | 2020-11-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
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2OXW
 | | Human MMP-12 complexed with the peptide IAG | | 分子名称: | CALCIUM ION, ILE-ALA-GLY peptide, Macrophage metalloelastase, ... | | 著者 | Calderone, V, Bertini, I, Fragai, M, Luchinat, C, Maletta, M, Yeo, K.J. | | 登録日 | 2007-02-21 | | 公開日 | 2007-03-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Snapshots of the reaction mechanism of matrix metalloproteinases.
ANGEW.CHEM.INT.ED.ENGL., 45, 2006
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1C16
 | | CRYSTAL STRUCTURE ANALYSIS OF THE GAMMA/DELTA T CELL LIGAND T22 | | 分子名称: | MHC-LIKE PROTEIN T22, PROTEIN (BETA-2-MICROGLOBULIN) | | 著者 | Wingren, C, Crowley, M.P, Degano, M, Chien, Y, Wilson, I.A. | | 登録日 | 1999-07-20 | | 公開日 | 2000-01-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of a gammadelta T cell receptor ligand T22: a truncated MHC-like fold.
Science, 287, 2000
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1C3Q
 | | CRYSTAL STRUCTURE OF NATIVE THIAZOLE KINASE IN THE MONOCLINIC FORM | | 分子名称: | 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, CHLORIDE ION, Hydroxyethylthiazole kinase | | 著者 | Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E. | | 登録日 | 1999-07-28 | | 公開日 | 1999-08-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
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6V6W
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3QNL
 | | Crystal structure of PrTX-I complexed to Rosmarinic Acid | | 分子名称: | (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ISOPROPYL ALCOHOL, ... | | 著者 | dos Santos, J.I, Fontes, M.R.M. | | 登録日 | 2011-02-08 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition.
Plos One, 6, 2011
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2WTO
 | | Crystal Structure of Apo-form Czce from C. metallidurans CH34 | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, ORF131 PROTEIN | | 著者 | Haertlein, I, Girard, E, Sarret, G, Hazemann, J, Gourhant, P, Kahn, R, Coves, J. | | 登録日 | 2009-09-18 | | 公開日 | 2010-08-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Evidence for Conformational Changes Upon Copper Binding to Cupriavidus Metallidurans Czce.
Biochemistry, 49, 2010
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6BPV
 | | Crystal structure of cysteine-bound ferrous form of the matured F2-Tyr157 human cysteine dioxygenase | | 分子名称: | CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ... | | 著者 | Liu, A, Li, J, Shin, I. | | 登録日 | 2017-11-26 | | 公開日 | 2018-07-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase.
Nat. Chem. Biol., 14, 2018
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4OTX
 | | Structure of the anti-Francisella tularensis O-antigen antibody N203 Fab fragment | | 分子名称: | AZIDE ION, CHLORIDE ION, N203 heavy chain, ... | | 著者 | Lu, Z, Rynkiewicz, M.J, Yang, C.-Y, Madico, G, Perkins, H.M, Roche, M.I, Seaton, B.A, Sharon, J. | | 登録日 | 2014-02-14 | | 公開日 | 2014-09-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Functional and Structural Characterization of Francisella tularensis O-Antigen Antibodies at the Low End of Antigen Reactivity.
Monoclon Antib Immunodiagn Immunother, 33, 2014
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7ZF5
 | | SARS-CoV-2 Omicron RBD in complex with Omi-12 and Beta-54 Fabs | | 分子名称: | Beta-54 heavy chain, Beta-54 light chain, Omi-12 heavy chain, ... | | 著者 | Zhou, D, Huo, J, Ren, J, Stuart, D.I. | | 登録日 | 2022-04-01 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (5.32 Å) | | 主引用文献 | Potent cross-reactive antibodies following Omicron breakthrough in vaccinees.
Cell, 185, 2022
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2J5T
 | | Glutamate 5-kinase from Escherichia coli complexed with glutamate | | 分子名称: | CHLORIDE ION, GLUTAMATE 5-KINASE, GLUTAMIC ACID, ... | | 著者 | Marco-Marin, C, Gil-Ortiz, F, Perez-Arellano, I, Cervera, J, Fita, I, Rubio, V. | | 登録日 | 2006-09-19 | | 公開日 | 2007-03-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
J.Mol.Biol., 367, 2007
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9B60
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2IVJ
 | | Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- cyclopropylglycine Fe Complex) | | 分子名称: | D-(L-A-AMINOADIPOYL)-L-CYSTEINYL-D-CYCLOPROPYLGLYCINE, FE (II) ION, ISOPENICILLIN N SYNTHETASE, ... | | 著者 | Howard-Jones, A.R, Elkins, J.M, Clifton, I.J, Roach, P.L, Adlington, R.M, Baldwin, J.E, Rutledge, P.J. | | 登録日 | 2006-06-13 | | 公開日 | 2007-04-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Interactions of Isopenicillin N Synthase with Cyclopropyl-Containing Substrate Analogues Reveal New Mechanistic Insight.
Biochemistry, 46, 2007
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2QD7
 | | HIV-1 Protease Mutant V82A with potent Antiviral inhibitor GRL-98065 | | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Wang, Y.F, Tie, Y, Boross, P.I, Tozser, J, Ghosh, A.K, Harrison, R.W, Weber, I.T. | | 登録日 | 2007-06-20 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | | 主引用文献 | Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease.
J.Med.Chem., 50, 2007
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6URS
 | | Sleeping Beauty transposase PAI subdomain mutant - H19Y | | 分子名称: | Sleeping Beauty transposase PAI subdomain | | 著者 | Nesmelova, I.V, Leighton, G.O, Yan, C, Lustig, J, Corona, R.I, Guo, J.T, Ivics, Z. | | 登録日 | 2019-10-24 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | H19Y mutation in the primary DNA-recognition subdomain of the Sleeping Beauty transposase improves structural stability, transposon DNA-binding and transposition
To Be Published
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2B61
 | | Crystal Structure of Homoserine Transacetylase | | 分子名称: | Homoserine O-acetyltransferase | | 著者 | Mirza, I.A, Nazi, I, Korczynska, M, Wright, G.D, Berghuis, A.M. | | 登録日 | 2005-09-29 | | 公開日 | 2005-11-15 | | 最終更新日 | 2018-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal Structure of Homoserine Transacetylase from Haemophilus influenzae Reveals a New Family of alpha/beta-Hydrolases
Biochemistry, 44, 2005
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5TTW
 | | Crystal Structure of EED in Complex with UNC4859 | | 分子名称: | Polycomb protein EED, SULFATE ION, UNC4859, ... | | 著者 | The, J, Barnash, K.D, Brown, P.J, Edwards, A.M, Bountra, C, Frye, S.V, James, L.I, Arrowsmith, C.H. | | 登録日 | 2016-11-04 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2.
ACS Comb Sci, 19, 2017
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7AZG
 | | DNA polymerase sliding clamp from Escherichia coli with peptide 4 bound | | 分子名称: | Beta sliding clamp, Peptide 4 | | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | | 登録日 | 2020-11-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
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4P2V
 | | Structure of the AI-2 processing enzyme LsrF in complex with the product of the LsrG reaction P-HPD | | 分子名称: | (3R)-3-hydroxy-2,4-dioxopentyl dihydrogen phosphate, Uncharacterized aldolase LsrF | | 著者 | Miller, S.T, Oh, I.K, Xavier, K.B. | | 登録日 | 2014-03-04 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | LsrF, a coenzyme A-dependent thiolase, catalyzes the terminal step in processing the quorum sensing signal autoinducer-2.
Proc.Natl.Acad.Sci.USA, 111, 2014
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7AZ8
 | | DNA polymerase sliding clamp from Escherichia coli with peptide 43 bound | | 分子名称: | Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | | 登録日 | 2020-11-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
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