2OXW
Human MMP-12 complexed with the peptide IAG
Summary for 2OXW
Entry DOI | 10.2210/pdb2oxw/pdb |
Related | 1RMZ 1Y93 2OXU 2OXZ 2OY2 2OY4 |
Descriptor | Macrophage metalloelastase, ILE-ALA-GLY peptide, ZINC ION, ... (5 entities in total) |
Functional Keywords | mmp-12, matrix metalloproteinase, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P39900 |
Total number of polymer chains | 2 |
Total formula weight | 18126.02 |
Authors | Calderone, V.,Bertini, I.,Fragai, M.,Luchinat, C.,Maletta, M.,Yeo, K.J. (deposition date: 2007-02-21, release date: 2007-03-06, Last modification date: 2023-08-30) |
Primary citation | Bertini, I.,Calderone, V.,Fragai, M.,Luchinat, C.,Maletta, M.,Yeo, K.J. Snapshots of the reaction mechanism of matrix metalloproteinases. ANGEW.CHEM.INT.ED.ENGL., 45:7952-7955, 2006 Cited by PubMed: 17096442DOI: 10.1002/anie.200603100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.15 Å) |
Structure validation
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