4P2V

Structure of the AI-2 processing enzyme LsrF in complex with the product of the LsrG reaction P-HPD

Summary for 4P2V

• Entry DOI: 10.2210/pdb4p2v/pdb
• Descriptor: Uncharacterized aldolase LsrF, (3R)-3-hydroxy-2,4-dioxopentyl dihydrogen phosphate (3 entities in total)
• Functional Keywords: thiolase, lyase
• Biological source: Escherichia coli
• Total number of polymer chains: 10
• Total formula weight: 322278.61

Authors

Miller, S.T.,Oh, I.K.,Xavier, K.B. (deposition date: 2014-03-04, release date: 2014-09-17, Last modification date: 2023-09-27)

• Primary citation: Marques, J.C.,Oh, I.K.,Ly, D.C.,Lamosa, P.,Ventura, M.R.,Miller, S.T.,Xavier, K.B.; LsrF, a coenzyme A-dependent thiolase, catalyzes the terminal step in processing the quorum sensing signal autoinducer-2.; Proc.Natl.Acad.Sci.USA, 111:14235-14240, 2014; PubMed: 25225400; DOI: 10.1073/pnas.1408691111

Experimental method

X-RAY DIFFRACTION (2.51 Å)