4P2V

Structure of the AI-2 processing enzyme LsrF in complex with the product of the LsrG reaction P-HPD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004332	molecular_function	fructose-bisphosphate aldolase activity
A	0005737	cellular_component	cytoplasm
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0016829	molecular_function	lyase activity
B	0004332	molecular_function	fructose-bisphosphate aldolase activity
B	0005737	cellular_component	cytoplasm
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0016829	molecular_function	lyase activity
C	0004332	molecular_function	fructose-bisphosphate aldolase activity
C	0005737	cellular_component	cytoplasm
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0016829	molecular_function	lyase activity
D	0004332	molecular_function	fructose-bisphosphate aldolase activity
D	0005737	cellular_component	cytoplasm
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0016829	molecular_function	lyase activity
E	0004332	molecular_function	fructose-bisphosphate aldolase activity
E	0005737	cellular_component	cytoplasm
E	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
E	0016829	molecular_function	lyase activity
F	0004332	molecular_function	fructose-bisphosphate aldolase activity
F	0005737	cellular_component	cytoplasm
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
F	0016829	molecular_function	lyase activity
G	0004332	molecular_function	fructose-bisphosphate aldolase activity
G	0005737	cellular_component	cytoplasm
G	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
G	0016829	molecular_function	lyase activity
H	0004332	molecular_function	fructose-bisphosphate aldolase activity
H	0005737	cellular_component	cytoplasm
H	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
H	0016829	molecular_function	lyase activity
I	0004332	molecular_function	fructose-bisphosphate aldolase activity
I	0005737	cellular_component	cytoplasm
I	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
I	0016829	molecular_function	lyase activity
K	0004332	molecular_function	fructose-bisphosphate aldolase activity
K	0005737	cellular_component	cytoplasm
K	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
K	0016829	molecular_function	lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue 26T A 301

Chain	Residue
A	HIS58
A	TYR205
A	GLY226
A	GLY227
A	ASP251
A	GLY253
A	ARG254
A	HOH446

---

site_id	AC2
Number of Residues	11
Details	binding site for residue 26T B 301

Chain	Residue
B	HIS58
B	TYR205
B	GLY226
B	GLY227
B	ASP251
B	MET252
B	GLY253
B	ARG254
B	HOH452
B	HOH473
B	ALA55

---

site_id	AC3
Number of Residues	12
Details	binding site for residue 26T C 301

Chain	Residue
C	ASP57
C	HIS58
C	GLN141
C	TYR205
C	GLY226
C	GLY227
C	ASP251
C	GLY253
C	ARG254
C	HOH439
C	HOH441
C	HOH464

---

site_id	AC4
Number of Residues	10
Details	binding site for residue 26T D 301

Chain	Residue
D	ASP57
D	HIS58
D	TYR60
D	PHE61
D	GLN141
D	ALA225
D	GLY226
D	GLY227
D	GLY253
D	ARG254

---

site_id	AC5
Number of Residues	14
Details	binding site for residue 26T E 301

Chain	Residue
E	HIS58
E	PHE61
E	GLN141
E	TYR205
E	GLY226
E	GLY227
E	ASP251
E	MET252
E	GLY253
E	ARG254
E	HOH452
E	HOH453
E	HOH467
E	HOH469

---

site_id	AC6
Number of Residues	11
Details	binding site for residue 26T F 301

Chain	Residue
F	ASP57
F	HIS58
F	TYR60
F	GLN141
F	GLY226
F	GLY227
F	ASP251
F	MET252
F	GLY253
F	ARG254
F	HOH481

---

site_id	AC7
Number of Residues	9
Details	binding site for residue 26T G 301

Chain	Residue
G	HIS58
G	TYR205
G	ALA225
G	GLY226
G	GLY227
G	ASP251
G	GLY253
G	ARG254
G	HOH435

---

site_id	AC8
Number of Residues	11
Details	binding site for residue 26T H 301

Chain	Residue
H	HIS58
H	TYR205
H	ALA225
H	GLY226
H	GLY227
H	ASP251
H	GLY253
H	ARG254
H	HOH425
H	HOH434
H	HOH438

---

site_id	AC9
Number of Residues	13
Details	binding site for residue 26T I 301

Chain	Residue
I	ALA55
I	ASP57
I	HIS58
I	TYR60
I	ARG107
I	ALA225
I	GLY226
I	GLY227
I	ASP251
I	GLY253
I	ARG254
I	HOH453
I	HOH462

---

site_id	AD1
Number of Residues	12
Details	binding site for residue 26T K 301

Chain	Residue
K	ALA55
K	ASP57
K	HIS58
K	ARG107
K	GLN141
K	GLY226
K	GLY227
K	ASP251
K	MET252
K	GLY253
K	ARG254
K	HOH430

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Active site: {"description":"Schiff-base intermediate with substrate","evidences":[{"source":"HAMAP-Rule","id":"MF_02052","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25225400","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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