1U8W
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![BU of 1u8w by Molmil](/molmil-images/mine/1u8w) | Crystal structure of Arabidopsis thaliana nucleoside diphosphate kinase 1 | 分子名称: | Nucleoside diphosphate kinase I | 著者 | Im, Y.J, Kim, J.-I, Shen, Y, Na, Y, Han, Y.-J, Kim, S.-H, Song, P.-S, Eom, S.H. | 登録日 | 2004-08-07 | 公開日 | 2004-11-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural analysis of Arabidopsis thaliana nucleoside diphosphate kinase-2 for phytochrome-mediated light signaling J.Mol.Biol., 343, 2004
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6SZQ
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![BU of 6szq by Molmil](/molmil-images/mine/6szq) | Crystal structure of human DDAH-1 | 分子名称: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | 著者 | Hennig, S, Vetter, I.R, Schade, D. | 登録日 | 2019-10-02 | 公開日 | 2019-12-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.412 Å) | 主引用文献 | Discovery ofN-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1). J.Med.Chem., 63, 2020
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8XI6
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![BU of 8xi6 by Molmil](/molmil-images/mine/8xi6) | SARS-CoV-2 Omicron BQ.1.1 Variant Spike Protein Complexed with MO11 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ishimaru, H, Nishimura, M, Shigematsu, H, Marini, M.I, Hasegawa, N, Takamiya, R, Iwata, S, Mori, Y. | 登録日 | 2023-12-19 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Epitopes of an antibody that neutralizes a wide range of SARS-CoV-2 variants in a conserved subdomain 1 of the spike protein. J.Virol., 98, 2024
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6F79
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![BU of 6f79 by Molmil](/molmil-images/mine/6f79) | |
6SC8
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![BU of 6sc8 by Molmil](/molmil-images/mine/6sc8) | dAb3/HOIP-RBR-Ligand4 | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase RNF31, SULFATE ION, ... | 著者 | Tsai, Y.-C.I, Johansson, H, House, D, Rittinger, K. | 登録日 | 2019-07-23 | 公開日 | 2019-11-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.106 Å) | 主引用文献 | Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases. Cell Chem Biol, 27, 2020
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6SC7
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![BU of 6sc7 by Molmil](/molmil-images/mine/6sc7) | dAb3/HOIP-RBR-Ligand3 | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase RNF31, SULFATE ION, ... | 著者 | Tsai, Y.-C.I, Johansson, H, House, D, Rittinger, K. | 登録日 | 2019-07-23 | 公開日 | 2019-11-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases. Cell Chem Biol, 27, 2020
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5IFA
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9ETU
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![BU of 9etu by Molmil](/molmil-images/mine/9etu) | |
9EQ7
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![BU of 9eq7 by Molmil](/molmil-images/mine/9eq7) | Halobacterium salinarum archaellum filament | 分子名称: | 2-O-sulfo-beta-D-glucopyranuronic acid-(1-4)-3-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-beta-D-glucopyranuronic acid-(1-4)-beta-D-glucopyranose, Archaellin | 著者 | Grossman-Haham, I, Shahar, A. | 登録日 | 2024-03-21 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Perturbed N-glycosylation of Halobacterium salinarum archaellum filaments leads to filament bundling and compromised cell motility. Nat Commun, 15, 2024
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7ZCK
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![BU of 7zck by Molmil](/molmil-images/mine/7zck) | Room temperature crystal structure of PhnD from Synechococcus MITS9220 in complex with phosphate | 分子名称: | CHLORIDE ION, PHOSPHATE ION, Phosphonate ABC type transporter/ substrate binding component | 著者 | Mikolajek, H, Shah, B.S, Paulsen, I.T, Sandy, J, Sanchez-Weatherby, J. | 登録日 | 2022-03-28 | 公開日 | 2022-05-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Protein-to-structure pipeline for ambient-temperature in situ crystallography at VMXi. Iucrj, 10, 2023
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5F3E
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![BU of 5f3e by Molmil](/molmil-images/mine/5f3e) | Crystal structure of human KDM4A in complex with compound 54a | 分子名称: | 8-[4-[2-[4-(4-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Le Bihan, Y.-V, Westwood, I.M, van Montfort, R.L.M. | 登録日 | 2015-12-02 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016
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1Y10
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![BU of 1y10 by Molmil](/molmil-images/mine/1y10) | Mycobacterial adenylyl cyclase Rv1264, holoenzyme, inhibited state | 分子名称: | CALCIUM ION, Hypothetical protein Rv1264/MT1302, PENTAETHYLENE GLYCOL | 著者 | Tews, I, Findeisen, F, Sinning, I, Schultz, A, Schultz, J.E, Linder, J.U. | 登録日 | 2004-11-16 | 公開日 | 2005-05-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme Science, 308, 2005
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6BPS
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![BU of 6bps by Molmil](/molmil-images/mine/6bps) | Crystal structure of cysteine-bound ferrous form of the uncrosslinked F2-Tyr157 human cysteine dioxygenase | 分子名称: | CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ... | 著者 | Liu, A, Li, J, Shin, I. | 登録日 | 2017-11-26 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nat. Chem. Biol., 14, 2018
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2WMR
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![BU of 2wmr by Molmil](/molmil-images/mine/2wmr) | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 分子名称: | 5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE, SERINE/THREONINE-PROTEIN KINASE CHK1 | 著者 | Matthews, T.P, Klair, S, Burns, S, Boxall, K, Cherry, M, Fisher, M, Westwood, I.M, Walton, M.I, McHardy, T, Cheung, K.-M.J, Van Montfort, R, Williams, D, Aherne, G.W, Garrett, M.D, Reader, J, Collins, I. | 登録日 | 2009-07-03 | 公開日 | 2009-07-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Identification of Inhibitors of Checkpoint Kinase 1 Through Template Screening. J.Med.Chem., 52, 2009
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6BGF
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![BU of 6bgf by Molmil](/molmil-images/mine/6bgf) | Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase | 分子名称: | CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ... | 著者 | Liu, A, Li, J, Shin, I. | 登録日 | 2017-10-28 | 公開日 | 2017-12-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | 主引用文献 | Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nat.Chem.Biol., 14, 2018
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5F37
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![BU of 5f37 by Molmil](/molmil-images/mine/5f37) | Crystal structure of human KDM4A in complex with compound 58 | 分子名称: | 1,2-ETHANEDIOL, 3H-pyrido[3,4-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, ... | 著者 | Le Bihan, Y.-V, Dempster, S, Westwood, I.M, van Montfort, R.L.M. | 登録日 | 2015-12-02 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016
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5F2W
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![BU of 5f2w by Molmil](/molmil-images/mine/5f2w) | Crystal structure of human KDM4A in complex with compound 16 | 分子名称: | 1,2-ETHANEDIOL, 2-(2-azanyl-1,3-thiazol-4-yl)pyridine-4-carboxamide, DIMETHYL SULFOXIDE, ... | 著者 | Le Bihan, Y.-V, Dempster, S, Westwood, I.M, van Montfort, R.L.M. | 登録日 | 2015-12-02 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016
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2OX8
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![BU of 2ox8 by Molmil](/molmil-images/mine/2ox8) | Human Scavenger Receptor C-type Lectin carbohydrate-recognition domain. | 分子名称: | CALCIUM ION, CHLORIDE ION, Scavenger receptor with C-type lectin type I, ... | 著者 | Weis, W.I, Feinberg, H, Drickamer, K, Taylor, M.E. | 登録日 | 2007-02-20 | 公開日 | 2007-04-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Scavenger receptor C-type lectin binds to the leukocyte cell surface glycan Lewis(x) by a novel mechanism. J.Biol.Chem., 282, 2007
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5F39
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![BU of 5f39 by Molmil](/molmil-images/mine/5f39) | Crystal structure of human KDM4A in complex with compound 37 | 分子名称: | 8-(1,3-thiazol-4-yl)-3~{H}-pyrido[3,4-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Lysine-specific demethylase 4A, ... | 著者 | Le Bihan, Y.-V, Dempster, S, Westwood, I.M, van Montfort, R.L.M. | 登録日 | 2015-12-02 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016
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3N0C
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![BU of 3n0c by Molmil](/molmil-images/mine/3n0c) | TM0449 mutant crystal grown by hanging drop method | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase thyX | 著者 | Mathews, I.I. | 登録日 | 2010-05-13 | 公開日 | 2011-05-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Diffraction study of protein crystals grown in cryoloops and micromounts. J.Appl.Crystallogr., 43, 2010
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7AZF
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![BU of 7azf by Molmil](/molmil-images/mine/7azf) | DNA polymerase sliding clamp from Escherichia coli with peptide 8 bound | 分子名称: | Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | 登録日 | 2020-11-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
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5F32
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![BU of 5f32 by Molmil](/molmil-images/mine/5f32) | Crystal structure of human KDM4A in complex with compound 40 | 分子名称: | 1,2-ETHANEDIOL, 8-(2-azanyl-1,3-thiazol-4-yl)-3~{H}-pyrido[3,4-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, ... | 著者 | Le Bihan, Y.-V, Dempster, S, Westwood, I.M, van Montfort, R.L.M. | 登録日 | 2015-12-02 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016
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9COJ
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![BU of 9coj by Molmil](/molmil-images/mine/9coj) | SH3-like tandem domain of human KIN protein | 分子名称: | DNA/RNA-binding protein KIN17 | 著者 | de Lourenco, I.O, Fossey, M.A, Souza, F.P, Seixas, F.A.V, Fernandez, M.A, Almeida, F.C.L, Caruso, I.P. | 登録日 | 2024-07-16 | 公開日 | 2024-07-31 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of SH3-like tandem domain of human KIN protein and its interaction with RNA homo-oligonucleotides To Be Published
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6EYP
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![BU of 6eyp by Molmil](/molmil-images/mine/6eyp) | X-ray structure of the unliganded uridine phosphorylase from Vibrio cholerae at 1.22A | 分子名称: | GLYCEROL, MAGNESIUM ION, SODIUM ION, ... | 著者 | Prokofev, I.I, Balaev, V.V, Gabdoulkhakov, A.G, Betzel, C, Lashkov, A.A. | 登録日 | 2017-11-13 | 公開日 | 2018-11-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | X-ray structure of the unliganded uridine phosphorylase from Vibrio cholerae at 1.22A To Be Published
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5RSF
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![BU of 5rsf by Molmil](/molmil-images/mine/5rsf) | PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000026180281 | 分子名称: | 9-methyl-9H-purine-2,6-diamine, Non-structural protein 3 | 著者 | Correy, G.J, Young, I.D, Thompson, M.C, Fraser, J.S. | 登録日 | 2020-09-28 | 公開日 | 2020-12-16 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Sci Adv, 7, 2021
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