7Z0W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z0w by Molmil](/molmil-images/mine/7z0w) | E. coli NfsA bound to NADP+ | 分子名称: | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, ... | 著者 | White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I. | 登録日 | 2022-02-23 | 公開日 | 2022-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism. Febs Lett., 596, 2022
|
|
7Q0O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q0o by Molmil](/molmil-images/mine/7q0o) | E. coli NfsA | 分子名称: | FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NADPH nitroreductase | 著者 | White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I. | 登録日 | 2021-10-15 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | 主引用文献 | The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism. Febs Lett., 596, 2022
|
|
6G7G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g7g by Molmil](/molmil-images/mine/6g7g) | Structure of SPH (Self-Incompatibility Protein Homologue) proteins, a widespread family of small, highly stable, secreted proteins from plants | 分子名称: | S-protein homolog 15 | 著者 | Rajasekar, K.V, Coulthard, R.J, Ride, J.P, Ji, S, Winn, P.J, Wheeler, M.P, Hyde, E.I, Smith, L.J. | 登録日 | 2018-04-06 | 公開日 | 2019-03-06 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of SPH (self-incompatibility protein homologue) proteins: a widespread family of small, highly stable, secreted proteins. Biochem.J., 476, 2019
|
|
8OG3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8og3 by Molmil](/molmil-images/mine/8og3) | E. coli NfsB triple mutant T41L/N71S/F124T bound to citrate | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, FLAVIN MONONUCLEOTIDE, ... | 著者 | Day, M.A, White, S.A, Hyde, E.I, Searle, P.F. | 登録日 | 2023-03-17 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
|
|
2N5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2n5g by Molmil](/molmil-images/mine/2n5g) | NMR structure of KorA, a plasmid-encoded, global transcription regulator KorA | 分子名称: | TrfB transcriptional repressor protein | 著者 | Rajasekar, K.V, Lovering, A.L, Dancea, F.V, Scott, D.J, Harris, S, Bingle, L.E, Roessle, M, Thomas, C.M, Hyde, E.I, White, S.A. | 登録日 | 2015-07-17 | 公開日 | 2016-07-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator. Nucleic Acids Res., 44, 2016
|
|
1YLU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ylu by Molmil](/molmil-images/mine/1ylu) | The structure of E. coli nitroreductase with bound acetate, crystal form 2 | 分子名称: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | 著者 | Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I. | 登録日 | 2005-01-19 | 公開日 | 2005-02-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme. J.Biol.Chem., 280, 2005
|
|
1YLR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ylr by Molmil](/molmil-images/mine/1ylr) | The structure of E.coli nitroreductase with bound acetate, crystal form 1 | 分子名称: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | 著者 | Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I. | 登録日 | 2005-01-19 | 公開日 | 2005-02-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme. J.Biol.Chem., 280, 2005
|
|
1YKI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yki by Molmil](/molmil-images/mine/1yki) | The structure of E. coli nitroreductase bound with the antibiotic nitrofurazone | 分子名称: | CITRIC ACID, DIMETHYL SULFOXIDE, FLAVIN MONONUCLEOTIDE, ... | 著者 | Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I. | 登録日 | 2005-01-18 | 公開日 | 2005-02-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme. J.Biol.Chem., 280, 2005
|
|
8AJX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ajx by Molmil](/molmil-images/mine/8ajx) | E. coli NfsA with Fumarate | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, FUMARIC ACID, ... | 著者 | Day, M.A, Jarrom, D, White, S.A, Hyde, E.I. | 登録日 | 2022-07-28 | 公開日 | 2023-01-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Oxygen-insensitive nitroreductase E. coli NfsA, but not NfsB, is inhibited by fumarate. Proteins, 91, 2023
|
|
8C5P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c5p by Molmil](/molmil-images/mine/8c5p) | E. coli NfsB mutant N71S T41L with acetate | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DIMETHYL SULFOXIDE, ... | 著者 | Day, M.A, White, S.A, Hyde, E.I. | 登録日 | 2023-01-10 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
|
|
8CCV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ccv by Molmil](/molmil-images/mine/8ccv) | E. coli NfsB mutant T41LN71S with nicotinate | 分子名称: | FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, Oxygen-insensitive NAD(P)H nitroreductase | 著者 | Day, M.A, White, S.A, Hyde, E.I, Searle, P.F. | 登録日 | 2023-01-27 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
|
|
8CJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cj0 by Molmil](/molmil-images/mine/8cj0) | E. coli NfsB-T41Q/N71S/F124T/M127V mutant bound to nicotinate | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... | 著者 | White, S.A, Hyde, E.I, Day, M.A. | 登録日 | 2023-02-11 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
|
|
8C5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c5e by Molmil](/molmil-images/mine/8c5e) | E. coli NfsB-T41Q/N71S/F124T mutant bound to nicotinic acid | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... | 著者 | White, S.A, Hyde, E.I, Day, M.A. | 登録日 | 2023-01-06 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
|
|
8C5F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c5f by Molmil](/molmil-images/mine/8c5f) | E. coli NfsB-T41Q/N71S/F124T mutant bound to acetate | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | White, S.A, Hyde, E.I, Day, M.A. | 登録日 | 2023-01-07 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
|
|
7NIY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7niy by Molmil](/molmil-images/mine/7niy) | E. coli NfsA with FMN | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | Day, M.D, Jarrom, D, Hyde, E.I, White, S.A. | 登録日 | 2021-02-14 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN. Biochem.J., 478, 2021
|
|
7NB9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nb9 by Molmil](/molmil-images/mine/7nb9) | E. coli NfsA with nitrofurantoin | 分子名称: | 1-[(~{E})-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione, DIMETHYL SULFOXIDE, FLAVIN MONONUCLEOTIDE, ... | 著者 | Day, M.D, Jarrom, D, Grainger, A.I, Parr, R.J, Hyde, E.I, White, S.A. | 登録日 | 2021-01-25 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN. Biochem.J., 478, 2021
|
|
7NNX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nnx by Molmil](/molmil-images/mine/7nnx) | E. coli NfsA with 1,4-benzoquinone | 分子名称: | 1,2-ETHANEDIOL, 1,4-benzoquinone, CHLORIDE ION, ... | 著者 | Day, M.D, Jarrom, D, Hyde, E.I, White, S.A. | 登録日 | 2021-02-25 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN. Biochem.J., 478, 2021
|
|
7NMP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nmp by Molmil](/molmil-images/mine/7nmp) | E. coli NfsA with hydroquinone | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Day, M.D, Jarrom, D, Parr, R.J, Hyde, E.I, White, S.A. | 登録日 | 2021-02-23 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN. Biochem.J., 478, 2021
|
|
1E9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e9k by Molmil](/molmil-images/mine/1e9k) | The structure of the RACK1 interaction sites located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5. | 分子名称: | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 著者 | Bolger, G.B, Smith, K.J, McCahill, A, Hyde, E.I, Steele, M.R, Houslay, M.D. | 登録日 | 2000-10-20 | 公開日 | 2001-10-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | 1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1. Cell. Signal., 19, 2007
|
|
1ICV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1icv by Molmil](/molmil-images/mine/1icv) | THE STRUCTURE OF ESCHERICHIA COLI NITROREDUCTASE COMPLEXED WITH NICOTINIC ACID | 分子名称: | FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE | 著者 | Lovering, A.L, Hyde, E.I, Searle, P.F, White, S.A. | 登録日 | 2001-04-02 | 公開日 | 2001-04-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution. J.Mol.Biol., 309, 2001
|
|
1ICU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1icu by Molmil](/molmil-images/mine/1icu) | THE STRUCTURE OF ESCHERICHIA COLI NITROREDUCTASE COMPLEXED WITH NICOTINIC ACID | 分子名称: | FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE | 著者 | Lovering, A.L, Hyde, E.I, Searle, P.F, White, S.A. | 登録日 | 2001-04-02 | 公開日 | 2001-04-18 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution. J.Mol.Biol., 309, 2001
|
|
1ICR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1icr by Molmil](/molmil-images/mine/1icr) | THE STRUCTURE OF ESCHERICHIA COLI NITROREDUCTASE COMPLEXED WITH NICOTINIC ACID | 分子名称: | FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE | 著者 | Lovering, A.L, Hyde, E.I, Searle, P.F, White, S.A. | 登録日 | 2001-04-02 | 公開日 | 2001-04-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution. J.Mol.Biol., 309, 2001
|
|
5CKT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ckt by Molmil](/molmil-images/mine/5ckt) | Crystal Structure of KorA, a plasmid-encoded, global transcription regulator | 分子名称: | ACETATE ION, TrfB transcriptional repressor protein | 著者 | White, S.A, Hyde, E.I, Lovering, A.L. | 登録日 | 2015-07-15 | 公開日 | 2016-04-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator. Nucleic Acids Res., 44, 2016
|
|
5CM3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cm3 by Molmil](/molmil-images/mine/5cm3) | Crystal Structure of KorA, a plasmid-encoded, global transcription regulator | 分子名称: | 5'-D(CP*CP*AP*AP*GP*TP*TP*TP*AP*GP*CP*TP*AP*AP*AP*CP*TP*TP*GP*GP*)-3', TrfB transcriptional repressor protein | 著者 | White, S.A, Hyde, E.I, Rajasekar, K.V. | 登録日 | 2015-07-16 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator. Nucleic Acids Res., 44, 2016
|
|
5CLV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5clv by Molmil](/molmil-images/mine/5clv) | Crystal Structure of KorA-operator DNA complex (KorA-OA) | 分子名称: | 5'-D(CP*CP*AP*AP*GP*TP*TP*TP*AP*GP*CP*TP*AP*AP*AP*CP*TP*TP*GP*GP*)-3', TrfB transcriptional repressor protein | 著者 | White, S.A, Hyde, E.I, Rajasekar, K.V. | 登録日 | 2015-07-16 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator. Nucleic Acids Res., 44, 2016
|
|