6NZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nzd by Molmil](/molmil-images/mine/6nzd) | Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) | 分子名称: | 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, Folliculin, Folliculin-interacting protein 2, ... | 著者 | Fromm, S.A, Young, L.N, Hurley, J.H. | 登録日 | 2019-02-13 | 公開日 | 2019-11-06 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Science, 366, 2019
|
|
5HM9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hm9 by Molmil](/molmil-images/mine/5hm9) | Crystal structure of MamO protease domain from Magnetospirillum magneticum (apo form) | 分子名称: | MamO protease domain, poly(UNK) | 著者 | Hershey, D.M, Ren, X, Hurley, J.H, Komeili, A. | 登録日 | 2016-01-15 | 公開日 | 2016-03-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | MamO Is a Repurposed Serine Protease that Promotes Magnetite Biomineralization through Direct Transition Metal Binding in Magnetotactic Bacteria. Plos Biol., 14, 2016
|
|
5HMA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hma by Molmil](/molmil-images/mine/5hma) | Crystal structure of MamO protease domain from Magnetospirillum magneticum (Ni bound form) | 分子名称: | CHLORIDE ION, NICKEL (II) ION, Trypsin-like serine protease, ... | 著者 | Hershey, D.M, Ren, X, Hurley, J.H, Komeili, A. | 登録日 | 2016-01-15 | 公開日 | 2016-02-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | MamO Is a Repurposed Serine Protease that Promotes Magnetite Biomineralization through Direct Transition Metal Binding in Magnetotactic Bacteria. Plos Biol., 14, 2016
|
|
5JW9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jw9 by Molmil](/molmil-images/mine/5jw9) | |
3EAB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eab by Molmil](/molmil-images/mine/3eab) | Crystal structure of Spastin MIT in complex with ESCRT III | 分子名称: | CHMP1b, Spastin | 著者 | Yang, D, Rimanchi, N, Renvoise, B, Lippincott-Schwartz, J, Blackstone, C, Hurley, J.H. | 登録日 | 2008-08-25 | 公開日 | 2008-11-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B. Nat.Struct.Mol.Biol., 15, 2008
|
|
3F1I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f1i by Molmil](/molmil-images/mine/3f1i) | Human ESCRT-0 Core Complex | 分子名称: | Hepatocyte growth factor-regulated tyrosine kinase substrate, Signal transducing adapter molecule 1 | 著者 | Ren, X, Kloer, D.P, Kim, Y, Ghirlando, R, Saidi, L, Hummer, G, Hurley, J.H. | 登録日 | 2008-10-28 | 公開日 | 2009-03-24 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Hybrid Structural Model of the Complete Human ESCRT-0 Complex. Structure, 17, 2009
|
|
6V4U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v4u by Molmil](/molmil-images/mine/6v4u) | Cryo-EM structure of SMCR8-C9orf72-WDR41 complex | 分子名称: | Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41 | 著者 | Su, M.Y, Hurley, J.H. | 登録日 | 2019-12-01 | 公開日 | 2020-09-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD. Nature, 585, 2020
|
|
3CUQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cuq by Molmil](/molmil-images/mine/3cuq) | |
3E1R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e1r by Molmil](/molmil-images/mine/3e1r) | Midbody targeting of the ESCRT machinery by a non-canonical coiled-coil in CEP55 | 分子名称: | Centrosomal protein of 55 kDa, Programmed cell death 6-interacting protein | 著者 | Lee, H.H, Elia, N, Ghirlando, R, Lippincott-Schwartz, J, Hurley, J.H. | 登録日 | 2008-08-04 | 公開日 | 2008-11-04 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55. Science, 322, 2008
|
|
6VME
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vme by Molmil](/molmil-images/mine/6vme) | Human ESCRT-I heterotetramer headpiece | 分子名称: | Multivesicular body subunit 12A, Tumor susceptibility gene 101 protein, Vacuolar protein sorting-associated protein 28 homolog, ... | 著者 | Flower, T.G, Hurley, J.H, Tjahjono, N. | 登録日 | 2020-01-27 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission. Nat.Struct.Mol.Biol., 27, 2020
|
|
6WCW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wcw by Molmil](/molmil-images/mine/6wcw) | Structure of human Rubicon RH domain in complex with GTP-bound Rab7 | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7a, ... | 著者 | Bhargava, H.K, Byck, J.M, Farrell, D.P, Anishchenko, I, DiMaio, F, Im, Y.J, Hurley, J.H. | 登録日 | 2020-03-31 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6WJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wj3 by Molmil](/molmil-images/mine/6wj3) | |
6WJ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wj2 by Molmil](/molmil-images/mine/6wj2) | CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the pre-GAP state | 分子名称: | 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Fromm, S.A, Hurley, J.H. | 登録日 | 2020-04-11 | 公開日 | 2020-09-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. Nat.Struct.Mol.Biol., 27, 2020
|
|
2F6M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f6m by Molmil](/molmil-images/mine/2f6m) | Structure of a Vps23-C:Vps28-N subcomplex | 分子名称: | DECYLAMINE-N,N-DIMETHYL-N-OXIDE, MAGNESIUM ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ... | 著者 | Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H. | 登録日 | 2005-11-29 | 公開日 | 2006-04-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and functional organization of the ESCRT-I trafficking complex. Cell(Cambridge,Mass.), 125, 2006
|
|
2FAU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fau by Molmil](/molmil-images/mine/2fau) | Crystal structure of human vps26 | 分子名称: | GLYCEROL, Vacuolar protein sorting 26 | 著者 | Shi, H, Rojas, R, Bonifacino, J.S, Hurley, J.H. | 登録日 | 2005-12-08 | 公開日 | 2006-05-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain. Nat.Struct.Mol.Biol., 13, 2006
|
|
2FID
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fid by Molmil](/molmil-images/mine/2fid) | |
2F66
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f66 by Molmil](/molmil-images/mine/2f66) | Structure of the ESCRT-I endosomal trafficking complex | 分子名称: | Protein SRN2, SULFATE ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ... | 著者 | Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H. | 登録日 | 2005-11-28 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and functional organization of the ESCRT-I trafficking complex. Cell(Cambridge,Mass.), 125, 2006
|
|
2FIF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fif by Molmil](/molmil-images/mine/2fif) | |
1GRO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gro by Molmil](/molmil-images/mine/1gro) | |
1GRP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1grp by Molmil](/molmil-images/mine/1grp) | |
3HTU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3htu by Molmil](/molmil-images/mine/3htu) | |
8D4F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d4f by Molmil](/molmil-images/mine/8d4f) | beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | 著者 | Hooy, R.M, Hurley, J.H. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | 主引用文献 | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
|
|
8D4E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d4e by Molmil](/molmil-images/mine/8d4e) | Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | 著者 | Hooy, R.M, Hurley, J.H. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (9.2 Å) | 主引用文献 | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
|
|
8D4G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d4g by Molmil](/molmil-images/mine/8d4g) | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | 著者 | Hooy, R.M, Hurley, J.H. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (11.6 Å) | 主引用文献 | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
|
|
8D4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d4d by Molmil](/molmil-images/mine/8d4d) | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | 著者 | Hooy, R.M, Hurley, J.H. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (9.6 Å) | 主引用文献 | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
|
|