6VME
Human ESCRT-I heterotetramer headpiece
Summary for 6VME
Entry DOI | 10.2210/pdb6vme/pdb |
Descriptor | Tumor susceptibility gene 101 protein, Vacuolar protein sorting-associated protein 37B, Multivesicular body subunit 12A, ... (5 entities in total) |
Functional Keywords | endosomal transport, hiv release, macroautophagy, protein transport |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 24 |
Total formula weight | 204222.14 |
Authors | Flower, T.G.,Hurley, J.H.,Tjahjono, N. (deposition date: 2020-01-27, release date: 2020-05-20, Last modification date: 2023-10-11) |
Primary citation | Flower, T.G.,Takahashi, Y.,Hudait, A.,Rose, K.,Tjahjono, N.,Pak, A.J.,Yokom, A.L.,Liang, X.,Wang, H.G.,Bouamr, F.,Voth, G.A.,Hurley, J.H. A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission. Nat.Struct.Mol.Biol., 27:570-580, 2020 Cited by PubMed: 32424346DOI: 10.1038/s41594-020-0426-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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