6V4U
Cryo-EM structure of SMCR8-C9orf72-WDR41 complex
Summary for 6V4U
| Entry DOI | 10.2210/pdb6v4u/pdb |
| EMDB information | 21048 |
| Descriptor | WD repeat-containing protein 41, Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8 (3 entities in total) |
| Functional Keywords | complex, trimer, autophagy, transport protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 211324.38 |
| Authors | Su, M.Y.,Hurley, J.H. (deposition date: 2019-12-01, release date: 2020-09-02, Last modification date: 2024-03-06) |
| Primary citation | Su, M.Y.,Fromm, S.A.,Zoncu, R.,Hurley, J.H. Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD. Nature, 585:251-255, 2020 Cited by PubMed: 32848248DOI: 10.1038/s41586-020-2633-x PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
Download full validation report
