3CUQ
 
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9C82
 | | Structure of human ULK1C:PI3KC3-C1 supercomplex | | 分子名称: | Beclin 1-associated autophagy-related key regulator, Beclin-1, Phosphatidylinositol 3-kinase catalytic subunit type 3, ... | | 著者 | Chen, M, Hurley, J.H. | | 登録日 | 2024-06-11 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (6.84 Å) | | 主引用文献 | Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
bioRxiv, 2023
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7UX3
 | | Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes | | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | 著者 | Hooy, R.M, Hurley, J.H. | | 登録日 | 2022-05-04 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (9.6 Å) | | 主引用文献 | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8SQZ
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8SOR
 | | Structure of human PI3KC3-C1 complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Beclin 1-associated autophagy-related key regulator, Beclin-1, ... | | 著者 | Chen, M, Hurley, J.H. | | 登録日 | 2023-04-29 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
bioRxiv, 2023
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8SOI
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8SRM
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7JTL
 | | Structure of SARS-CoV-2 ORF8 accessory protein | | 分子名称: | ORF8 protein, SODIUM ION | | 著者 | Flower, T.G, Buffalo, C.Z, Hooy, R.M, Allaire, M, Ren, X, Hurley, J.H. | | 登録日 | 2020-08-18 | | 公開日 | 2020-08-26 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6NZD
 | | Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) | | 分子名称: | 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, Folliculin, Folliculin-interacting protein 2, ... | | 著者 | Fromm, S.A, Young, L.N, Hurley, J.H. | | 登録日 | 2019-02-13 | | 公開日 | 2019-11-06 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Science, 366, 2019
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6OWT
 | | Structure of SIVsmm Nef and SMM tetherin bound to the clathrin adaptor AP-2 complex | | 分子名称: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit sigma, ... | | 著者 | Buffalo, C.Z, Ren, X, Hurley, J.H. | | 登録日 | 2019-05-10 | | 公開日 | 2019-09-25 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural Basis for Tetherin Antagonism as a Barrier to Zoonotic Lentiviral Transmission.
Cell Host Microbe, 26, 2019
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6PAS
 | | Inactive State of Manduca sexta soluble guanylate cyclase | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Soluble guanylyl cyclase alpha-1 subunit, Soluble guanylyl cyclase beta-1 subunit | | 著者 | Yokom, A.L, Horst, B.G, Marletta, M.A, Hurley, J.H. | | 登録日 | 2019-06-11 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | | 主引用文献 | Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy.
Elife, 8, 2019
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6PAT
 | | Active State of Manduca sexta soluble Guanylate Cyclase | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Soluble guanylyl cyclase alpha-1 subunit, Soluble guanylyl cyclase beta-1 subunit | | 著者 | Yokom, A.L, Horst, B.G, Marletta, M.A, Hurley, J.H. | | 登録日 | 2019-06-11 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy.
Elife, 8, 2019
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5C50
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7MU2
 | | Crystal Structure of WIPI2 in complex with W2IR of ATG16L1 | | 分子名称: | Autophagy-related protein 16-1, WD repeat domain phosphoinositide-interacting protein 2 | | 著者 | Strong, L.M, Flower, T.G, Buffalo, C.Z, Hurley, J.H. | | 登録日 | 2021-05-14 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy.
Elife, 10, 2021
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7MGE
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4HMY
 | | Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1 | | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | 著者 | Ren, X, Farias, G.G, Canagarajah, B.J, Bonifacino, J.S, Hurley, J.H. | | 登録日 | 2012-10-18 | | 公開日 | 2013-03-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (7 Å) | | 主引用文献 | Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1.
Cell(Cambridge,Mass.), 152, 2013
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4HPQ
 | | Crystal Structure of the Atg17-Atg31-Atg29 Complex | | 分子名称: | Atg17, Atg29, Atg31 | | 著者 | Stanley, R.E, Ragusa, M.J, Hurley, J.H. | | 登録日 | 2012-10-24 | | 公開日 | 2012-12-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | Architecture of the atg17 complex as a scaffold for autophagosome biogenesis.
Cell(Cambridge,Mass.), 151, 2012
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2ZME
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4J2G
 | | Atg13 HORMA domain | | 分子名称: | KLTH0A00704p, SULFATE ION | | 著者 | Jao, C, Stanley, R.E, Ragusa, M.J, Hurley, J.H. | | 登録日 | 2013-02-04 | | 公開日 | 2013-03-20 | | 最終更新日 | 2013-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4IKN
 | | Crystal structure of adaptor protein complex 3 (AP-3) mu3A subunit C-terminal domain, in complex with a sorting peptide from TGN38 | | 分子名称: | AP-3 complex subunit mu-1, Trans-Golgi network integral membrane protein TGN38 | | 著者 | Mardones, G.A, Kloer, D.P, Burgos, P.V, Bonifacino, J.S, Hurley, J.H. | | 登録日 | 2012-12-26 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | | 主引用文献 | Structural basis for the recognition of tyrosine-based sorting signals by the mu 3A subunit of the AP-3 adaptor complex.
J.Biol.Chem., 288, 2013
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4K7H
 | | Major capsid protein P1 of the Pseudomonas phage phi6 | | 分子名称: | Major inner protein P1 | | 著者 | Boura, E, Nemecek, D, Plevka, P, Steven, C.A, Hurley, J.H. | | 登録日 | 2013-04-17 | | 公開日 | 2013-08-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.5964 Å) | | 主引用文献 | Subunit Folds and Maturation Pathway of a dsRNA Virus Capsid.
Structure, 21, 2013
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3EAB
 | | Crystal structure of Spastin MIT in complex with ESCRT III | | 分子名称: | CHMP1b, Spastin | | 著者 | Yang, D, Rimanchi, N, Renvoise, B, Lippincott-Schwartz, J, Blackstone, C, Hurley, J.H. | | 登録日 | 2008-08-25 | | 公開日 | 2008-11-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B.
Nat.Struct.Mol.Biol., 15, 2008
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3F1I
 | | Human ESCRT-0 Core Complex | | 分子名称: | Hepatocyte growth factor-regulated tyrosine kinase substrate, Signal transducing adapter molecule 1 | | 著者 | Ren, X, Kloer, D.P, Kim, Y, Ghirlando, R, Saidi, L, Hummer, G, Hurley, J.H. | | 登録日 | 2008-10-28 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Hybrid Structural Model of the Complete Human ESCRT-0 Complex.
Structure, 17, 2009
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6CYT
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3E1R
 | | Midbody targeting of the ESCRT machinery by a non-canonical coiled-coil in CEP55 | | 分子名称: | Centrosomal protein of 55 kDa, Programmed cell death 6-interacting protein | | 著者 | Lee, H.H, Elia, N, Ghirlando, R, Lippincott-Schwartz, J, Hurley, J.H. | | 登録日 | 2008-08-04 | | 公開日 | 2008-11-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55.
Science, 322, 2008
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