8SOR

Structure of human PI3KC3-C1 complex

Summary for 8SOR

Entry DOI	10.2210/pdb8sor/pdb
Related	8SOR 8SQZ 8SRM 8SRQ
EMDB information	40669 41055 41056 41057
Descriptor	Phosphatidylinositol 3-kinase catalytic subunit type 3, Beclin 1-associated autophagy-related key regulator, Beclin-1, ... (5 entities in total)
Functional Keywords	autophagy, lipid kinase, complex, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	362741.69
Authors	Chen, M.,Hurley, J.H. (deposition date: 2023-04-29, release date: 2023-06-21, Last modification date: 2024-10-09)
Primary citation	Chen, M.,Ren, X.,Cook, A.,Hurley, J.H. Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex bioRxiv, 2023 Cited by DOI: 10.1101/2023.06.01.543278 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.96 Å)

Structure validation