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13BV

Cryo-EM structure of human PI3KC3-C1 complex

Replaces:  8SOR
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Phosphatidylinositol 3-kinase catalytic subunit type 3polymer887101680.31UniProt (Q8NEB9)Homo sapiens (human)PI3-kinase type 3,PI3K type 3,PtdIns-3-kinase type 3,Phosphatidylinositol 3-kinase p100 subunit,Phosphoinositide-3-kinase class 3,hVps34
2B
(C)
Beclin 1-associated autophagy-related key regulatorpolymer49255387.31UniProt (Q6ZNE5)Homo sapiens (human)
3C
(D)
Beclin-1polymer45051953.11UniProt (Q14457)Homo sapiens (human)Coiled-coil myosin-like BCL2-interacting protein,Protein GT197
4D
(A)
Phosphoinositide 3-kinase regulatory subunit 4polymer1358153293.81UniProt (Q99570)Homo sapiens (human)PI3-kinase regulatory subunit 4,PI3-kinase p150 subunit,Phosphoinositide 3-kinase adaptor protein
5E
(A)
MYRISTIC ACIDnon-polymer228.41Chemie (MYR)
6F
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
7G
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight362314.5
Non-Polymers*Number of molecules3
Total formula weight695.9
All*Total formula weight363010.4
*Water molecules are not included.

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PDB entries from 2026-05-13

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