6OWT
Structure of SIVsmm Nef and SMM tetherin bound to the clathrin adaptor AP-2 complex
Summary for 6OWT
Entry DOI | 10.2210/pdb6owt/pdb |
EMDB information | 20217 |
Descriptor | AP-2 complex subunit alpha, AP-2 complex subunit beta, Adaptor protein complex AP-2, mu1, ... (5 entities in total) |
Functional Keywords | ap, hiv, nef, trafficking, protein transport, viral restriction factor |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 6 |
Total formula weight | 267957.52 |
Authors | Buffalo, C.Z.,Ren, X.,Hurley, J.H. (deposition date: 2019-05-10, release date: 2019-09-25, Last modification date: 2019-12-18) |
Primary citation | Buffalo, C.Z.,Sturzel, C.M.,Heusinger, E.,Kmiec, D.,Kirchhoff, F.,Hurley, J.H.,Ren, X. Structural Basis for Tetherin Antagonism as a Barrier to Zoonotic Lentiviral Transmission. Cell Host Microbe, 26:359-368.e8, 2019 Cited by PubMed: 31447307DOI: 10.1016/j.chom.2019.08.002 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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