7MU2

Crystal Structure of WIPI2 in complex with W2IR of ATG16L1

Summary for 7MU2

Entry DOI	10.2210/pdb7mu2/pdb
Descriptor	WD repeat domain phosphoinositide-interacting protein 2, Autophagy-related protein 16-1 (3 entities in total)
Functional Keywords	autophagy, wipi2, atg16, lipid binding protein
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	77208.52
Authors	Strong, L.M.,Flower, T.G.,Buffalo, C.Z.,Hurley, J.H. (deposition date: 2021-05-14, release date: 2021-05-26, Last modification date: 2023-10-18)
Primary citation	Strong, L.M.,Chang, C.,Riley, J.F.,Boecker, C.A.,Flower, T.G.,Buffalo, C.Z.,Ren, X.,Stavoe, A.K.,Holzbaur, E.L.,Hurley, J.H. Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy. Elife, 10:-, 2021 Cited by PubMed: 34505572 DOI: 10.7554/eLife.70372 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation