7JQ9
 
 | | Cryo-EM structure of human HUWE1 | | 分子名称: | E3 ubiquitin-protein ligase HUWE1 | | 著者 | Hunkeler, M, Fischer, E.S. | | 登録日 | 2020-08-10 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
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6G2I
 | | Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) at 5.9 A resolution | | 分子名称: | Acetyl-CoA carboxylase 1, Breast cancer type 1 susceptibility protein | | 著者 | Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T. | | 登録日 | 2018-03-23 | | 公開日 | 2018-06-13 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
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6G2H
 | | Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) core at 4.6 A resolution | | 分子名称: | Acetyl-CoA carboxylase 1 | | 著者 | Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T. | | 登録日 | 2018-03-23 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
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6G2D
 | | Citrate-induced acetyl-CoA carboxylase (ACC-Cit) filament at 5.4 A resolution | | 分子名称: | Acetyl-CoA carboxylase 1 | | 著者 | Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T. | | 登録日 | 2018-03-23 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | | 主引用文献 | Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
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7MWD
 | | HUWE1 in map with focus on HECT | | 分子名称: | E3 ubiquitin-protein ligase HUWE1 | | 著者 | Hunkeler, M, Fischer, E.S. | | 登録日 | 2021-05-16 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
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7MWF
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7MWE
 | | HUWE1 in map with focus on WWE | | 分子名称: | E3 ubiquitin-protein ligase HUWE1 | | 著者 | Hunkeler, M, Fischer, E.S. | | 登録日 | 2021-05-16 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
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7MOP
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5I6F
 | | Crystal structure of C-terminal variant 1 of Chaetomium thermophilum acetyl-CoA carboxylase | | 分子名称: | Acetyl-CoA carboxylase-like protein | | 著者 | Hunkeler, M, Stuttfeld, E, Hagmann, A, Imseng, S, Maier, T. | | 登録日 | 2016-02-16 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | The dynamic organization of fungal acetyl-CoA carboxylase.
Nat Commun, 7, 2016
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5I6G
 | | Crystal structure of C-terminal variant 2 of Chaetomium thermophilum acetyl-CoA carboxylase | | 分子名称: | Acetyl-CoA carboxylase-like protein,Acetyl-CoA carboxylase-like protein | | 著者 | Hunkeler, M, Stuttfeld, E, Hagmann, A, Imseng, S, Maier, T. | | 登録日 | 2016-02-16 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | The dynamic organization of fungal acetyl-CoA carboxylase.
Nat Commun, 7, 2016
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5I6I
 | | Crystal structure of a dBCCP-variant of Chaetomium thermophilum acetyl-CoA carboxylase | | 分子名称: | Acetyl-CoA carboxylase-like protein,Acetyl-CoA carboxylase-like protein,Acetyl-CoA carboxylase-like protein | | 著者 | Hunkeler, M, Stuttfeld, E, Hagmann, A, Imseng, S, Maier, T. | | 登録日 | 2016-02-16 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (8.4 Å) | | 主引用文献 | The dynamic organization of fungal acetyl-CoA carboxylase.
Nat Commun, 7, 2016
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5I6E
 | | Crystal structure of the central domain of yeast acetyl-CoA carboxylase | | 分子名称: | Acetyl-CoA carboxylase, MALONATE ION | | 著者 | Hunkeler, M, Stuttfeld, E, Hagmann, A, Imseng, S, Maier, T. | | 登録日 | 2016-02-16 | | 公開日 | 2016-04-20 | | 最終更新日 | 2016-04-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The dynamic organization of fungal acetyl-CoA carboxylase.
Nat Commun, 7, 2016
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5I6H
 | | Crystal structure of CD-CT domains of Chaetomium thermophilum acetyl-CoA carboxylase | | 分子名称: | Acetyl-CoA carboxylase-like protein | | 著者 | Hunkeler, M, Stuttfeld, E, Hagmann, A, Imseng, S, Maier, T. | | 登録日 | 2016-02-16 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (7.2 Å) | | 主引用文献 | The dynamic organization of fungal acetyl-CoA carboxylase.
Nat Commun, 7, 2016
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8E2D
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8E2G
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8E2J
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8E2E
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8E2I
 | | Cryo-EM structure of BIRC6/Smac | | 分子名称: | Baculoviral IAP repeat-containing protein 6, Diablo IAP-binding mitochondrial protein | | 著者 | Hunkeler, M, Fischer, E.S. | | 登録日 | 2022-08-15 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Science, 379, 2023
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8E2F
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8E2K
 | | Cryo-EM structure of BIRC6/HtrA2-S306A | | 分子名称: | Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial | | 著者 | Hunkeler, M, Fischer, E.S. | | 登録日 | 2022-08-15 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Science, 379, 2023
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8E2H
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9B9V
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9B9R
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8G46
 | | Cryo-EM structure of DDB1deltaB-DDA1-DCAF16-BRD4(BD2)-MMH2 | | 分子名称: | Bromodomain-containing protein 4, DDB1- and CUL4-associated factor 16, DET1- and DDB1-associated protein 1, ... | | 著者 | Ma, M.W, Hunkeler, M, Jin, C.Y, Fischer, E.S. | | 登録日 | 2023-02-08 | | 公開日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders.
Biorxiv, 2023
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6XMX
 | | Cryo-EM structure of BCL6 bound to BI-3802 | | 分子名称: | 2-[6-[[5-chloranyl-2-[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxidanylidene-quinolin-3-yl]oxy-~{N}-methyl-ethanamide, B-cell lymphoma 6 protein | | 著者 | Yoon, H, Burman, S.S.R, Hunkeler, M, Nowak, R.P, Fischer, E.S. | | 登録日 | 2020-07-01 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Small-molecule-induced polymerization triggers degradation of BCL6.
Nature, 588, 2020
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