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PDB: 292 件

6RR9
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DNA/RNA binding protein
分子名称: GLYCEROL, SULFATE ION, Schlafen family member 5, ...
著者Huber, E, Lammens, K.
登録日2019-05-17
公開日2020-07-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (3.432 Å)
主引用文献Structural and biochemical characterization of human Schlafen 5.
Nucleic Acids Res., 2022
4G92
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BU of 4g92 by Molmil
CCAAT-binding complex from Aspergillus nidulans with DNA
分子名称: DNA, HAPB protein, HapE, ...
著者Huber, E.M, Scharf, D.H, Hortschansky, P, Groll, M, Brakhage, A.A.
登録日2012-07-23
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献DNA Minor Groove Sensing and Widening by the CCAAT-Binding Complex.
Structure, 20, 2012
4G91
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CCAAT-binding complex from Aspergillus nidulans
分子名称: HAPB protein, HapE, Transcription factor HapC (Eurofung)
著者Huber, E.M, Scharf, D.H, Hortschansky, P, Groll, M, Brakhage, A.A.
登録日2012-07-23
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献DNA Minor Groove Sensing and Widening by the CCAAT-Binding Complex.
Structure, 20, 2012
7Q3Z
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DNA/RNA binding protein
分子名称: SODIUM ION, Schlafen family member 5, ZINC ION
著者Huber, E, Lammens, K.
登録日2021-10-29
公開日2022-01-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and biochemical characterization of human Schlafen 5.
Nucleic Acids Res., 50, 2022
7AW9
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BU of 7aw9 by Molmil
CCAAT-binding complex and HapX bound to Aspergillus fumigatus cccA DNA
分子名称: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ...
著者Huber, E.M, Groll, M.
登録日2020-11-06
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX.
Structure, 30, 2022
7AW7
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BU of 7aw7 by Molmil
CCAAT-binding complex and HapX bound to Aspergillus nidulans cccA DNA
分子名称: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ...
著者Huber, E.M, Groll, M.
登録日2020-11-06
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX.
Structure, 30, 2022
5JHR
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BU of 5jhr by Molmil
Yeast 20S proteasome in complex with the peptidic epoxyketone inhibitor 27
分子名称: (2S)-2-azido-N-[(2S)-3-(biphenyl-4-yl)-1-{[(2S)-1-{[(2S,3S,4R)-3,5-dihydroxy-4-methylpentan-2-yl]amino}-1-oxo-3-phenylpropan-2-yl]amino}-1-oxopropan-2-yl]-3-phenylpropanamide (non-preferred name), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Huber, E.M, Groll, M.
登録日2016-04-21
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-Based Design of beta 5c Selective Inhibitors of Human Constitutive Proteasomes.
J.Med.Chem., 59, 2016
5JHS
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Yeast 20S proteasome in complex with the peptidic epoxyketone inhibitor 15
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2016-04-21
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure-Based Design of beta 5c Selective Inhibitors of Human Constitutive Proteasomes.
J.Med.Chem., 59, 2016
5BXL
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BU of 5bxl by Molmil
Yeast 20S proteasome beta2-G170A mutant
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Groll, M.
登録日2015-06-09
公開日2016-06-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.
Sci Rep, 8, 2018
5BXN
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Yeast 20S proteasome beta2-G170A mutant in complex with Bortezomib
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ...
著者Huber, E.M, Groll, M.
登録日2015-06-09
公開日2016-06-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.
Sci Rep, 8, 2018
5FGE
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Yeast 20S proteasome beta5-H(-2)T-T1A double mutant in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-12-20
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FGD
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BU of 5fgd by Molmil
Yeast 20S proteasome beta5-H(-2)L-T1A double mutant in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-12-20
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FGH
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BU of 5fgh by Molmil
Yeast 20S proteasome beta5-K33A mutant (propeptide expressed in trans) in complex with MG132
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide, ...
著者Huber, E.M, Groll, M.
登録日2015-12-20
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FGI
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BU of 5fgi by Molmil
Yeast 20S proteasome beta1-T1A beta2-T1A double mutant in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-12-20
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FGG
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BU of 5fgg by Molmil
Yeast 20S proteasome beta5-L(-49S)_D17N double mutant in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-12-20
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FHS
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BU of 5fhs by Molmil
Yeast 20S proteasome beta5-K33A mutant (propeptide expressed in trans) in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-12-22
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FGF
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BU of 5fgf by Molmil
Yeast 20S proteasome beta5-H(-2)A-T1A-K81R triple mutant in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-12-20
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FGA
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BU of 5fga by Molmil
Yeast 20S proteasome beta5-K33A mutant (propeptide expressed in trans)
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Groll, M.
登録日2015-12-20
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FG7
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BU of 5fg7 by Molmil
Yeast 20S proteasome beta2-T1A mutant
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Groll, M.
登録日2015-12-20
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FG9
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BU of 5fg9 by Molmil
Yeast 20S proteasome beta2-T(-2)V mutant
分子名称: MAGNESIUM ION, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ...
著者Huber, E.M, Groll, M.
登録日2015-12-20
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5CZ5
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BU of 5cz5 by Molmil
Yeast 20S proteasome beta1-T1A mutant in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-07-31
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5D0W
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BU of 5d0w by Molmil
Yeast 20S proteasome beta5-T1S mutant
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Groll, M.
登録日2015-08-03
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5D0S
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BU of 5d0s by Molmil
Yeast 20S proteasome beta5-D166N mutant in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-08-03
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5D0T
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BU of 5d0t by Molmil
Yeast 20S proteasome beta5-D166N mutant in complex with MG132
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide, ...
著者Huber, E.M, Groll, M.
登録日2015-08-03
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5CZ8
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BU of 5cz8 by Molmil
Yeast 20S proteasome beta5-L(-49)S-K33A mutant in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-07-31
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016

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