5FGA

Yeast 20S proteasome beta5-K33A mutant (propeptide expressed in trans)

Summary for 5FGA

Related5CZ4
DescriptorProteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ... (17 entities in total)
Functional Keywordshydrolase complex, proteasome, mutant, binding analysis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceSaccharomyces cerevisiae S288c (Baker's yeast)
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Total number of polymer chains28
Total molecular weight731199.92
Authors
Huber, E.M.,Groll, M. (deposition date: 2015-12-20, release date: 2016-03-23, Last modification date: 2018-10-24)
Primary citation
Huber, E.M.,Heinemeyer, W.,Li, X.,Arendt, C.S.,Hochstrasser, M.,Groll, M.
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7:10900-10900, 2016
PubMed: 26964885 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms10900
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2182 0.3% 3.9% 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution