7V3A
| Crystal structure of apo-NP exonuclease C409A | Descriptor: | MAGNESIUM ION, Nucleoprotein, ZINC ION | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V38
| Crystal structure of NP exonuclease-PCMPS complex | Descriptor: | Nucleoprotein, PARA-MERCURY-BENZENESULFONIC ACID, ZINC ION | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V3C
| Crystal structure of NP exonuclease C409A-PCMB complex | Descriptor: | 4-(HYDROXYMERCURY)BENZOIC ACID, MAGNESIUM ION, Nucleoprotein, ... | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V39
| Crystal structure of NP exonuclease-PCMB complex | Descriptor: | 4-(HYDROXYMERCURY)BENZOIC ACID, Nucleoprotein, ZINC ION | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V37
| Crystal structure of apo-NP exonuclease | Descriptor: | Nucleoprotein, ZINC ION | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V3B
| Crystal structure of NP exonuclease C409A-PCMPS complex | Descriptor: | MAGNESIUM ION, Nucleoprotein, PARA-MERCURY-BENZENESULFONIC ACID, ... | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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8HCG
| Crystal structure of mTREX1-dAMP complex | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | Deposit date: | 2022-11-01 | Release date: | 2023-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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8HCD
| Crystal structure of mTREX1-DNA product complex (dNMP) | Descriptor: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, COBALT (II) ION, ... | Authors: | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | Deposit date: | 2022-11-01 | Release date: | 2023-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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8HCE
| Crystal structure of mTREX1-CMP complex | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMMONIUM ION, CYTIDINE-5'-MONOPHOSPHATE, ... | Authors: | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | Deposit date: | 2022-11-01 | Release date: | 2023-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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8HCF
| Crystal structure of mTREX1-UMP complex | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Three-prime repair exonuclease 1, ... | Authors: | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | Deposit date: | 2022-11-01 | Release date: | 2023-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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8HCC
| Crystal structure of mTREX1-RNA product complex (AMP) | Descriptor: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, SODIUM ION, ... | Authors: | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | Deposit date: | 2022-11-01 | Release date: | 2023-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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8HCH
| Crystal structure of mTREX1-Uridine complex | Descriptor: | MAGNESIUM ION, Three-prime repair exonuclease 1, URIDINE | Authors: | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | Deposit date: | 2022-11-01 | Release date: | 2023-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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