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PDB: 347 results

7SZ1
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BU of 7sz1 by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR L834R bound to EGF. "tips-separated" conformation
Descriptor: Epidermal growth factor, Epidermal growth factor receptor
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-25
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
7SYD
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BU of 7syd by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR bound to EGF "tips-juxtaposed" conformation
Descriptor: Epidermal growth factor, Epidermal growth factor receptor
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-24
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
7SZ5
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BU of 7sz5 by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR bound to TGF-alpha "tips-separated" conformation
Descriptor: Epidermal growth factor receptor, Transforming growth factor alpha
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-25
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
7SYE
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BU of 7sye by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR bound to EGF. "tips-separated" conformation
Descriptor: Epidermal growth factor, Epidermal growth factor receptor
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-24
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
7SZ0
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BU of 7sz0 by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR L834R bound to EGF. "tips-juxtaposed" conformation
Descriptor: Epidermal growth factor, Epidermal growth factor receptor
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-25
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
3X2R
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BU of 3x2r by Molmil
Structure of the nonameric bacterial amyloid secretion channel CsgG
Descriptor: CsgG
Authors:Huang, Y, Cao, B, Zhao, Y, Kou, Y, Ni, D, Zhang, X.C.
Deposit date:2014-12-29
Release date:2015-01-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the nonameric bacterial amyloid secretion channel
Proc.Natl.Acad.Sci.USA, 111, 2014
2FMM
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BU of 2fmm by Molmil
Crystal Structure of EMSY-HP1 complex
Descriptor: Chromobox protein homolog 1, Protein EMSY, SULFATE ION
Authors:Huang, Y.
Deposit date:2006-01-09
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 binding.
Structure, 14, 2006
2IJG
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BU of 2ijg by Molmil
Crystal Structure of cryptochrome 3 from Arabidopsis thaliana
Descriptor: 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, Cryptochrome DASH, chloroplast/mitochondrial, ...
Authors:Huang, Y, Deisenhofer, J.
Deposit date:2006-09-29
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity
Proc.Natl.Acad.Sci.Usa, 103, 2006
7Y3Z
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BU of 7y3z by Molmil
Structure of a novel carboxylesterase FEH from Acinetobacter sp. DL-2
Descriptor: Fenoxaprop-p-ethyl hydrolase
Authors:Huang, Y, Liu, W.D, Zhang, Y.J, Duan, Y.J, Lu, M.L.
Deposit date:2022-06-13
Release date:2023-07-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a novel carboxylesterase FEH from Acinetobacter sp. DL-2
To Be Published
3MJ0
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BU of 3mj0 by Molmil
Crystal Structure of Drosophia Ago-PAZ domain in complex with 3'-end 2'-O-methylated RNA
Descriptor: Protein argonaute-2, RNA (5'-R(*CP*GP*UP*UP*AP*CP*GP*CP*(OMU))-3')
Authors:Huang, Y, Ding, L, Ma, J.
Deposit date:2010-04-12
Release date:2011-05-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:Crystal Structure of drosophila Ago2 PAZ domain in complex with 3'-end 2'-O-methylated RNA
To be Published
5Y83
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BU of 5y83 by Molmil
Crystal structure of YidC from Thermotoga maritima
Descriptor: Membrane protein insertase YidC
Authors:Huang, Y, Xin, Y.
Deposit date:2017-08-18
Release date:2018-07-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.842 Å)
Cite:Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion
FASEB J., 32, 2018
5Y82
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BU of 5y82 by Molmil
Crystal structure of the periplasmic domain of the Thermotoga maritima YidC
Descriptor: Membrane protein insertase YidC
Authors:Huang, Y, Xin, Y.
Deposit date:2017-08-18
Release date:2018-07-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.517 Å)
Cite:Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion
FASEB J., 32, 2018
6IEW
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BU of 6iew by Molmil
The crystal structure of the dNxf2 UBA domain in complex with Panoramix
Descriptor: Fusion protein of Nuclear RNA export factor 2 and Protein panoramix, GLYCEROL
Authors:Huang, Y, Cheng, S.
Deposit date:2018-09-17
Release date:2019-08-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation.
Nat.Cell Biol., 21, 2019
8GTD
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BU of 8gtd by Molmil
Cryo-EM model of the marine siphophage vB_DshS-R4C portal-adaptor complex
Descriptor: Head-to-tail joining protein, Portal protein
Authors:Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
Deposit date:2022-09-08
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8GTF
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BU of 8gtf by Molmil
Cryo-EM model of the marine siphophage vB_DshS-R4C stopper-terminator complex
Descriptor: Head-to-tail joining protein, Major tail protein, Terminator protein
Authors:Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
Deposit date:2022-09-08
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8GTB
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BU of 8gtb by Molmil
Cryo-EM structure of the marine siphophage vB_DshS-R4C tail tube protein
Descriptor: Major tail protein
Authors:Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
Deposit date:2022-09-08
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8GTC
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BU of 8gtc by Molmil
Cryo-EM model of the marine siphophage vB_DshS-R4C baseplate-tail complex
Descriptor: Distal tail protein, Hub protein, Major tail protein, ...
Authors:Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
Deposit date:2022-09-08
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
6A6L
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BU of 6a6l by Molmil
Crystal structure of the cold shock domain of YB-1 in complex with m5C RNA
Descriptor: Nuclease-sensitive element-binding protein 1, RNA (5'-R(P*CP*AP*UP*(5MC))-3')
Authors:Huang, Y.
Deposit date:2018-06-28
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of the cold shock domain of YB-1 in complex with m5C RNA
To Be Published
6IHJ
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BU of 6ihj by Molmil
Crystal structure of Drosophila Nxf1 NTF2 domain in complex with Nxt1/p15
Descriptor: NTF2-related export protein, Nuclear RNA export factor 1
Authors:Huang, Y, Yuan, X.
Deposit date:2018-09-30
Release date:2019-08-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation.
Nat.Cell Biol., 21, 2019
7CFG
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BU of 7cfg by Molmil
Structure of the transmembrane domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with Mg2+
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Hemolysin, MAGNESIUM ION, ...
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-02-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter.
Sci Adv, 7, 2021
7CFF
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BU of 7cff by Molmil
Structure of the thermostabilized transmembrane domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with Mg2+
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hemolysin, ...
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-02-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter.
Sci Adv, 7, 2021
7CFH
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BU of 7cfh by Molmil
Structure of the CBS domain of the bacterial CNNM/CorC family Mg2+ transporter
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Hemolysin
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-02-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter.
Sci Adv, 7, 2021
7CFI
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BU of 7cfi by Molmil
Structure of the CBS domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Hemolysin, MAGNESIUM ION
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter.
Sci Adv, 7, 2021
7CFK
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BU of 7cfk by Molmil
Structure of the CBS domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with the novel inhibitor IGN95a
Descriptor: (2S)-2-[(6-azanyl-9H-purin-8-yl)sulfanyl]butanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Hemolysin
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-04-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification and mechanistic analysis of an inhibitor of the CorC Mg 2+ transporter.
Iscience, 24, 2021
7Y0A
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BU of 7y0a by Molmil
Crystal structure of human short-chain acyl-CoA dehydrogenase
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, Short-chain specific acyl-CoA dehydrogenase, ...
Authors:Huang, Y, Xu, Y, Li, J.
Deposit date:2022-06-04
Release date:2023-07-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.317 Å)
Cite:Crystal structure of human short-chain acyl-CoA dehydrogenase
To Be Published

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