8JXU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jxu by Molmil](/molmil-images/mine/8jxu) | Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 2, ... | Authors: | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2023-07-01 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
|
|
8JXQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jxq by Molmil](/molmil-images/mine/8jxq) | Cryo-EM structure of bilirubin ditaurate (BDT) bound human ABC transporter ABCC2 | Descriptor: | 2-[3-[5-[(E)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-3-[3-oxidanylidene-3-(2-sulfoethylamino)propyl]-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoylamino]ethanesulfonic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL | Authors: | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2023-07-01 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
|
|
8J3W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j3w by Molmil](/molmil-images/mine/8j3w) | Cryo-EM structure of aspirin-bound ABCC4 | Descriptor: | 2-(ACETYLOXY)BENZOIC ACID, ATP-binding cassette sub-family C member 4 | Authors: | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | Deposit date: | 2023-04-18 | Release date: | 2023-05-24 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
|
|
8JX7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jx7 by Molmil](/molmil-images/mine/8jx7) | Cryo-EM structure of human ABC transporter ABCC2 | Descriptor: | ATP-binding cassette sub-family C member 2 | Authors: | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2023-06-30 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
|
|
8JY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jy5 by Molmil](/molmil-images/mine/8jy5) | Cryo-EM structure of human ABC transporter ABCC2 in apo" state | Descriptor: | ATP-binding cassette sub-family C member 2 | Authors: | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2023-07-03 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.17 Å) | Cite: | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
|
|
8JY4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jy4 by Molmil](/molmil-images/mine/8jy4) | Cryo-EM structure of human ABC transporter ABCC2 in apo' state | Descriptor: | ATP-binding cassette sub-family C member 2 | Authors: | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2023-07-02 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
|
|
8U10
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u10 by Molmil](/molmil-images/mine/8u10) | In situ cryo-EM structure of bacteriophage P22 gp1:gp4:gp5:gp10:gp9 N-term complex in conformation 1 at 3.2A resolution | Descriptor: | Major capsid protein, Packaged DNA stabilization protein gp10, Peptidoglycan hydrolase gp4, ... | Authors: | Iglesias, S, Feng-Hou, C, Cingolani, G. | Deposit date: | 2023-08-30 | Release date: | 2023-11-22 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery. J.Mol.Biol., 435, 2023
|
|
8U11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u11 by Molmil](/molmil-images/mine/8u11) | In situ cryo-EM structure of bacteriophage P22 gp1:gp5:gp4: gp10: gp9 N-term complex in conformation 2 at 3.1A resolution | Descriptor: | Major capsid protein, Packaged DNA stabilization protein gp10, Peptidoglycan hydrolase gp4, ... | Authors: | Iglesias, S, Feng-Hou, C, Cingolani, G. | Deposit date: | 2023-08-30 | Release date: | 2023-11-22 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery. J.Mol.Biol., 435, 2023
|
|
8TVU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tvu by Molmil](/molmil-images/mine/8tvu) | |
8TVR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tvr by Molmil](/molmil-images/mine/8tvr) | |
8U1O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u1o by Molmil](/molmil-images/mine/8u1o) | |
6B3T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b3t by Molmil](/molmil-images/mine/6b3t) | Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with a 1,2,4-triazino[5,6b]indole-3-thioether inhibitor analogue 39b | Descriptor: | 8-fluoro-5-methyl-3-{[2-(piperidin-1-yl)ethyl]sulfanyl}-5H-[1,2,4]triazino[5,6-b]indole, COENZYME A, N-acetyltransferase Eis, ... | Authors: | Gajadeera, C.S, Hou, C, Garneau-Tsodikova, S, Ngo, H.X, Tsodikov, O.V. | Deposit date: | 2017-09-24 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Potent 1,2,4-Triazino[5,6 b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis. ACS Infect Dis, 4, 2018
|
|
7SFS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sfs by Molmil](/molmil-images/mine/7sfs) | |
7SG7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sg7 by Molmil](/molmil-images/mine/7sg7) | |
7SP4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sp4 by Molmil](/molmil-images/mine/7sp4) | In situ cryo-EM structure of bacteriophage Sf6 gp3:gp7:gp5 complex in conformation 2 at 3.71A resolution | Descriptor: | Gene 3 protein, Gene 5 protein, Gene 7 protein | Authors: | Li, F, Cingolani, G, Hou, C, Yang, R. | Deposit date: | 2021-11-02 | Release date: | 2022-11-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine. Sci Adv, 8, 2022
|
|
7SPU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7spu by Molmil](/molmil-images/mine/7spu) | In situ cryo-EM structure of bacteriophage Sf6 gp3:gp7:gp5 complex in conformation 1 at 3.73A resolution | Descriptor: | Gene 3 protein, Gene 5 protein, Gene 7 protein | Authors: | Li, F, Cingolani, G, Hou, C, Yang, R. | Deposit date: | 2021-11-03 | Release date: | 2022-11-23 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine. Sci Adv, 8, 2022
|
|
7UXE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uxe by Molmil](/molmil-images/mine/7uxe) | Pseudomonas phage E217 small terminase (TerS) | Descriptor: | Small terminase | Authors: | Lokareddy, R.K, Hou, C.-F.D, Doll, S.G, Li, F, Gillilan, R, Forti, F, Briani, F, Cingolani, G. | Deposit date: | 2022-05-05 | Release date: | 2022-09-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Terminase Subunits from the Pseudomonas-Phage E217. J.Mol.Biol., 434, 2022
|
|
7UKJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ukj by Molmil](/molmil-images/mine/7ukj) | |
7FDV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7fdv by Molmil](/molmil-images/mine/7fdv) | Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 1, CHOLESTEROL, ... | Authors: | Xu, D, Li, Y.Y, Yang, F.R, Sun, C.R, Pan, J.H, Wang, L, Chen, Z.P, Fang, S.C, Yao, X.B, Hou, W.T, Zhou, C.Z, Chen, Y. | Deposit date: | 2021-07-18 | Release date: | 2022-06-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structure and transport mechanism of the human cholesterol transporter ABCG1. Cell Rep, 38, 2022
|
|
5XU1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xu1 by Molmil](/molmil-images/mine/5xu1) | Structure of a non-canonical ABC transporter from Streptococcus pneumoniae R6 | Descriptor: | ABC transporter ATP-binding protein, ABC transporter permeae, MAGNESIUM ION | Authors: | Yang, H.B, Jiang, Y.L, Hou, W.T, Chen, M.T, Chen, Y, Zhou, C.Z. | Deposit date: | 2017-06-22 | Release date: | 2018-01-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of a MacAB-like efflux pump from Streptococcus pneumoniae. Nat Commun, 9, 2018
|
|
5XU0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xu0 by Molmil](/molmil-images/mine/5xu0) | Structure of the membrane fusion protein Spr0693 from Streptococcus pneumoniae R6 | Descriptor: | Membrane-fusion protein | Authors: | Yang, H.B, Jiang, Y.L, Hou, W.T, Chen, M.T, Chen, Y, Zhou, C.Z. | Deposit date: | 2017-06-22 | Release date: | 2018-01-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of a MacAB-like efflux pump from Streptococcus pneumoniae. Nat Commun, 9, 2018
|
|
8EON
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8eon by Molmil](/molmil-images/mine/8eon) | Pseudomonas phage E217 baseplate complex | Descriptor: | Baseplate component gp33, Baseplate component gp34, Baseplate component gp36, ... | Authors: | Li, F, Cingolani, G, Hou, C. | Deposit date: | 2022-10-03 | Release date: | 2023-07-26 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217. Nat Commun, 14, 2023
|
|
8ENV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8env by Molmil](/molmil-images/mine/8env) | In situ cryo-EM structure of Pseudomonas phage E217 tail baseplate in C6 map | Descriptor: | Baseplate_J domain-containing protein gp44, Ripcord gp36, Sheath initiator gp34, ... | Authors: | Li, F, Cingolani, G, Hou, C. | Deposit date: | 2022-09-30 | Release date: | 2023-07-26 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217. Nat Commun, 14, 2023
|
|
4I5V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i5v by Molmil](/molmil-images/mine/4i5v) | Crystal structure of yeast Ap4A phosphorylase Apa2 in complex with Ap4A | Descriptor: | 5',5'''-P-1,P-4-tetraphosphate phosphorylase 2, BIS(ADENOSINE)-5'-TETRAPHOSPHATE | Authors: | Jiang, Y.L, Hou, W.T, Chen, Y, Zhou, C.Z. | Deposit date: | 2012-11-29 | Release date: | 2013-05-08 | Last modified: | 2014-02-05 | Method: | X-RAY DIFFRACTION (2.696 Å) | Cite: | Structures of yeast Apa2 reveal catalytic insights into a canonical AP4A phosphorylase of the histidine triad superfamily J.Mol.Biol., 425, 2013
|
|
4I5T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i5t by Molmil](/molmil-images/mine/4i5t) | Crystal structure of yeast Ap4A phosphorylase Apa2 | Descriptor: | 5',5'''-P-1,P-4-tetraphosphate phosphorylase 2 | Authors: | Jiang, Y.L, Hou, W.T, Chen, Y, Zhou, C.Z. | Deposit date: | 2012-11-29 | Release date: | 2013-05-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of yeast Apa2 reveal catalytic insights into a canonical AP4A phosphorylase of the histidine triad superfamily J.Mol.Biol., 425, 2013
|
|