4PDS
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![BU of 4pds by Molmil](/molmil-images/mine/4pds) | Crystal structure of Rad53 kinase domain and SCD2 in complex with AMPPNP | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase RAD53 | 著者 | Ho, C.S, Wybenga-Groot, L.E, Ceccarelli, D.F, Sicheri, F. | 登録日 | 2014-04-21 | 公開日 | 2014-05-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of Rad53 kinase activation by dimerization and activation segment exchange. Cell Signal., 26, 2014
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6PEV
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6E10
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![BU of 6e10 by Molmil](/molmil-images/mine/6e10) | PTEX Core Complex in the Engaged (Extended) State | 分子名称: | Endogenous cargo polypeptide, Exported protein 2, Heat shock protein 101, ... | 著者 | Ho, C, Lai, M, Zhou, Z.H. | 登録日 | 2018-07-08 | 公開日 | 2018-08-22 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Malaria parasite translocon structure and mechanism of effector export. Nature, 561, 2018
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6E11
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![BU of 6e11 by Molmil](/molmil-images/mine/6e11) | PTEX Core Complex in the Resetting (Compact) State | 分子名称: | Endogenous cargo polypeptide, Exported protein 2, Heat shock protein 101, ... | 著者 | Ho, C, Lai, M, Zhou, Z.H. | 登録日 | 2018-07-08 | 公開日 | 2018-08-22 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (4.23 Å) | 主引用文献 | Malaria parasite translocon structure and mechanism of effector export. Nature, 561, 2018
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1VWT
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![BU of 1vwt by Molmil](/molmil-images/mine/1vwt) | T STATE HUMAN HEMOGLOBIN [ALPHA V96W], ALPHA AQUOMET, BETA DEOXY | 分子名称: | HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Puius, Y.A, Zou, M, Ho, N.T, Ho, C, Almo, S.C. | 登録日 | 1997-03-20 | 公開日 | 1998-03-25 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp). Biochemistry, 37, 1998
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1RVW
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![BU of 1rvw by Molmil](/molmil-images/mine/1rvw) | R STATE HUMAN HEMOGLOBIN [ALPHA V96W], CARBONMONOXY | 分子名称: | CARBON MONOXIDE, HEMOGLOBIN, PHOSPHATE ION, ... | 著者 | Puius, Y.A, Zou, M, Ho, N.T, Ho, C, Almo, S.C. | 登録日 | 1997-03-20 | 公開日 | 1998-03-25 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp). Biochemistry, 37, 1998
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3VRE
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![BU of 3vre by Molmil](/molmil-images/mine/3vre) | The crystal structure of hemoglobin from woolly mammoth in the deoxy form | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | 登録日 | 2012-04-09 | 公開日 | 2012-11-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structures of haemoglobin from woolly mammoth in liganded and unliganded states. Acta Crystallogr.,Sect.D, 68, 2012
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3VRG
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![BU of 3vrg by Molmil](/molmil-images/mine/3vrg) | The crystal structure of hemoglobin from woolly mammoth in the met form | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | 登録日 | 2012-04-09 | 公開日 | 2012-11-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structures of haemoglobin from woolly mammoth in liganded and unliganded states. Acta Crystallogr.,Sect.D, 68, 2012
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3VRF
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![BU of 3vrf by Molmil](/molmil-images/mine/3vrf) | The crystal structure of hemoglobin from woolly mammoth in the carbonmonoxy forms | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, ... | 著者 | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | 登録日 | 2012-04-09 | 公開日 | 2012-11-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structures of haemoglobin from woolly mammoth in liganded and unliganded states. Acta Crystallogr.,Sect.D, 68, 2012
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3KB2
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![BU of 3kb2 by Molmil](/molmil-images/mine/3kb2) | Crystal Structure of YorR protein in complex with phosphorylated GDP from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR256 | 分子名称: | GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE, MAGNESIUM ION, SPBc2 prophage-derived uncharacterized protein yorR | 著者 | Forouhar, F, Friedman, D, Seetharaman, J, Janjua, J, Xiao, R, Cunningham, K, Ma, L, Ho, C, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-20 | 公開日 | 2009-10-27 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target SR256 To be Published
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6WGK
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![BU of 6wgk by Molmil](/molmil-images/mine/6wgk) | Fab portion of dupilumab with Crystal Kappa design and intrachain disulfide | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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6WGL
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![BU of 6wgl by Molmil](/molmil-images/mine/6wgl) | Dupilumab fab with Crystal Kappa design complexed with human IL-4 receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dupilumab Fab heavy chain, ... | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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4PDP
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6WG8
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![BU of 6wg8 by Molmil](/molmil-images/mine/6wg8) | Fab portion of dupilumab with Crystal Kappa design | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain, GLYCEROL | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2020-09-23 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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6WGJ
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![BU of 6wgj by Molmil](/molmil-images/mine/6wgj) | Fab portion of dupilumab with Crystal Kappa design and no interchain disulfide | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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6WGB
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![BU of 6wgb by Molmil](/molmil-images/mine/6wgb) | Crystal structure of the fab portion of dupilumab | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2020-09-23 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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4LLY
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![BU of 4lly by Molmil](/molmil-images/mine/4lly) | Crystal structure of Pertuzumab Clambda Fab with variable and constant domain redesigns (VRD2 and CRD2) at 1.6A | 分子名称: | GLYCEROL, MAGNESIUM ION, light chain Clambda, ... | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | 登録日 | 2013-07-09 | 公開日 | 2014-01-29 | 最終更新日 | 2019-06-26 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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4LLQ
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![BU of 4llq by Molmil](/molmil-images/mine/4llq) | Structure of redesigned IgG1 first constant and lambda domains (CH1:Clambda constant redesign 2 beta, CRD2b) at 1.42A | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, mutated CH1, mutated light chain Clambda | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | 登録日 | 2013-07-09 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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4LLU
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![BU of 4llu by Molmil](/molmil-images/mine/4llu) | Structure of Pertuzumab Fab with light chain Clambda at 2.16A | 分子名称: | ACETATE ION, Light chain CLAMBDA, PERTUZUMAB FAB Heavy chain, ... | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | 登録日 | 2013-07-09 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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4LLM
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![BU of 4llm by Molmil](/molmil-images/mine/4llm) | Structure of redesigned IgG1 first constant and lambda domains (CH1:Clambda constant redesign 1, CRD1) at 1.75A | 分子名称: | Ig gamma-1 chain C region, Ig lambda-2 chain C region | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | 登録日 | 2013-07-09 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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4LLW
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![BU of 4llw by Molmil](/molmil-images/mine/4llw) | Crystal structure of Pertuzumab Clambda Fab with variable domain redesign (VRD2) at 1.95A | 分子名称: | SULFATE ION, light chain Clambda, mutated Pertuzumab Fab heavy chain | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | 登録日 | 2013-07-09 | 公開日 | 2014-01-29 | 最終更新日 | 2019-06-26 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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4LLD
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![BU of 4lld by Molmil](/molmil-images/mine/4lld) | Structure of wild-type IgG1 antibody heavy chain constant domain 1 and light chain lambda constant domain (IgG1 CH1:Clambda) at 1.19A | 分子名称: | Ig gamma-1 chain C region, Ig lambda-2 chain C region | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | 登録日 | 2013-07-09 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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2GZP
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![BU of 2gzp by Molmil](/molmil-images/mine/2gzp) | Solution NMR structure of Q8ZP25 from Salmonella typhimurium LT2; Northeast Structural Genomics Consortium Target STR70 | 分子名称: | putative chaperone | 著者 | Parish, D, Liu, G, Shen, Y, Ho, C, Cunningham, K, Xiao, R, Swapna, G.V.T, Acton, T.B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-05-11 | 公開日 | 2006-06-27 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of Q8ZP24 from Salmonella typhimurium LT2. To be Published
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1F0X
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![BU of 1f0x by Molmil](/molmil-images/mine/1f0x) | CRYSTAL STRUCTURE OF D-LACTATE DEHYDROGENASE, A PERIPHERAL MEMBRANE RESPIRATORY ENZYME. | 分子名称: | D-LACTATE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Dym, O, Pratt, E.A, Ho, C, Eisenberg, D. | 登録日 | 2000-05-17 | 公開日 | 2000-08-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme. Proc.Natl.Acad.Sci.USA, 97, 2000
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2JZT
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![BU of 2jzt by Molmil](/molmil-images/mine/2jzt) | Solution NMR structure of Q8ZP25_SALTY from Salmonella typhimurium. Northeast Structural Genomics Consortium target StR70 | 分子名称: | Putative thiol-disulfide isomerase and thioredoxin | 著者 | Parish, D, Liu, G, Shen, Y, Ho, C, Cunningham, K, Xiao, R, Swapna, G.V.T, Acton, T, Bansal, S, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-01-16 | 公開日 | 2008-02-19 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Protein chaperones Q8ZP25_SALTY from Salmonella typhimurium and HYAE_ECOLI from Escherichia coli exhibit thioredoxin-like structures despite lack of canonical thioredoxin active site sequence motif. J.STRUCT.FUNCT.GENOM., 9, 2008
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