3BQL
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1T5E
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![BU of 1t5e by Molmil](/molmil-images/mine/1t5e) | The structure of MexA | Descriptor: | D-Glyceraldehyde, GLYCEROL, Multidrug resistance protein mexA | Authors: | Higgins, M.K, Bokma, E, Koronakis, E, Hughes, C, Koronakis, V. | Deposit date: | 2004-05-04 | Release date: | 2004-05-18 | Last modified: | 2020-07-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the periplasmic component of a bacterial drug efflux pump Proc.Natl.Acad.Sci.USA, 101, 2004
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1TQQ
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![BU of 1tqq by Molmil](/molmil-images/mine/1tqq) | Structure of TolC in complex with hexamminecobalt | Descriptor: | COBALT HEXAMMINE(III), Outer membrane protein tolC | Authors: | Higgins, M.K, Eswaran, J, Edwards, P.C, Schertler, G.F, Hughes, C, Koronakis, V. | Deposit date: | 2004-06-18 | Release date: | 2004-07-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug effllux protein TolC J.Mol.Biol., 342, 2004
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3BQK
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3BQI
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4E40
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![BU of 4e40 by Molmil](/molmil-images/mine/4e40) | The haptoglobin-hemoglobin receptor of Trypanosoma congolense | Descriptor: | Putative uncharacterized protein | Authors: | Higgins, M.K, Tkachenko, O, Brown, A, Reed, J, Carrington, M. | Deposit date: | 2012-03-11 | Release date: | 2013-01-16 | Last modified: | 2013-02-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunity. Proc.Natl.Acad.Sci.USA, 110, 2013
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4V3E
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![BU of 4v3e by Molmil](/molmil-images/mine/4v3e) | The CIDRa domain from IT4var07 PfEMP1 bound to endothelial protein C receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOTHELIAL PROTEIN C RECEPTOR, ... | Authors: | Lau, C.K.Y, Turner, L, Jespersen, J.S, Lowe, E.D, Petersen, B, Wang, C.W, Petersen, J.E.V, Lusingu, J, Theander, T.G, Lavstsen, T, Higgins, M.K. | Deposit date: | 2014-10-17 | Release date: | 2014-12-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria. Cell Host Microbe., 17, 2015
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5MZA
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![BU of 5mza by Molmil](/molmil-images/mine/5mza) | The DBLb domain of PF11_0521 PfEMP1 bound to human ICAM-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Erythrocyte membrane protein 1 (PfEMP1), ... | Authors: | Lennartz, F, Higgins, M.K. | Deposit date: | 2017-01-31 | Release date: | 2017-03-22 | Last modified: | 2020-10-07 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria. Cell Host Microbe, 21, 2017
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6R2S
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6H5N
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8RZ2
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8RZ0
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8RZ1
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8CDE
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8CDD
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4X0J
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![BU of 4x0j by Molmil](/molmil-images/mine/4x0j) | Trypanosoma brucei haptoglobin-haemoglobin receptor | Descriptor: | Haptoglobin-hemoglobin receptor | Authors: | Lane-Serff, H, MacGregor, P, Lowe, E.D, Carrington, M, Higgins, M.K. | Deposit date: | 2014-11-21 | Release date: | 2014-12-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor. Elife, 3, 2014
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4X0L
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![BU of 4x0l by Molmil](/molmil-images/mine/4x0l) | Human haptoglobin-haemoglobin complex | Descriptor: | CACODYLATE ION, GLYCEROL, Haptoglobin, ... | Authors: | Lane-Serff, H, MacGregor, P, Lowe, E.D, Carrington, M, Higgins, M.K. | Deposit date: | 2014-11-21 | Release date: | 2014-12-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor. Elife, 3, 2014
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5HU6
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5JDO
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6ELU
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4U1G
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![BU of 4u1g by Molmil](/molmil-images/mine/4u1g) | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody QA1 | Descriptor: | QA1 monoclonal antibody heavy chain, QA1 monoclonal antibody light chain, Reticulocyte binding protein 5 | Authors: | Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K. | Deposit date: | 2014-07-15 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies. Nature, 515, 2014
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4U0Q
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![BU of 4u0q by Molmil](/molmil-images/mine/4u0q) | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to basigin | Descriptor: | Basigin, Reticulocyte binding protein 5 | Authors: | Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K. | Deposit date: | 2014-07-14 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies. Nature, 515, 2014
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4V3D
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![BU of 4v3d by Molmil](/molmil-images/mine/4v3d) | The CIDRa domain from HB3var03 PfEMP1 bound to endothelial protein C receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOTHELIAL PROTEIN C RECEPTOR, ... | Authors: | Lau, C.K.Y, Turner, L, Jespersen, J.S, Lowe, E.D, Petersen, B, Wang, C.W, Petersen, J.E.V, Lusingu, J, Theander, T.G, Lavstsen, T, Higgins, M.K. | Deposit date: | 2014-10-17 | Release date: | 2014-12-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria. Cell Host Microbe., 17, 2015
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7PI3
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7PHV
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![BU of 7phv by Molmil](/molmil-images/mine/7phv) | PfCyRPA bound to monoclonal antibody Cy.007 Fab fragment | Descriptor: | AMMONIUM ION, Cysteine-rich protective antigen, Monoclonal antibody Cy.007 heavy chain, ... | Authors: | Ragotte, R.J, Higgins, M.K. | Deposit date: | 2021-08-18 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.091 Å) | Cite: | Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
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