4V3E

The CIDRa domain from IT4var07 PfEMP1 bound to endothelial protein C receptor

Summary for 4V3E

• Entry DOI: 10.2210/pdb4v3e/pdb
• Related: 4V3D
• Descriptor: IT4VAR07 CIDRA, ENDOTHELIAL PROTEIN C RECEPTOR, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: signaling protein, pfemp1, epcr, malaria, cidr domain, endothelial protein c receptor, plasmodium falciparum
• Biological source: PLASMODIUM FALCIPARUM (MALARIA PARASITE P. FALCIPARUM); More
• Total number of polymer chains: 2
• Total formula weight: 51395.97

Authors

Lau, C.K.Y.,Turner, L.,Jespersen, J.S.,Lowe, E.D.,Petersen, B.,Wang, C.W.,Petersen, J.E.V.,Lusingu, J.,Theander, T.G.,Lavstsen, T.,Higgins, M.K. (deposition date: 2014-10-17, release date: 2014-12-17, Last modification date: 2024-01-10)

• Primary citation: Lau, C.K.Y.,Turner, L.,Jespersen, J.S.,Lowe, E.D.,Petersen, B.,Wang, C.W.,Petersen, J.E.V.,Lusingu, J.,Theander, T.G.,Lavstsen, T.,Higgins, M.K.; Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria.; Cell Host Microbe., 17:118-, 2015; PubMed: 25482433; DOI: 10.1016/J.CHOM.2014.11.007

Experimental method

X-RAY DIFFRACTION (2.9 Å)