5T01
| Human c-Jun DNA binding domain homodimer in complex with methylated DNA | 分子名称: | DNA (5'-D(*AP*AP*TP*GP*GP*AP*(5CM)P*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*G)-3'), DNA (5'-D(P*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*GP*TP*CP*CP*AP*T)-3'), Transcription factor AP-1 | 著者 | Hong, S, Horton, J.R, Cheng, X. | 登録日 | 2016-08-15 | 公開日 | 2017-03-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. Nucleic Acids Res., 45, 2017
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2ZO2
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5V3M
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5V3J
| mouseZFP568-ZnF1-10 in complex with DNA | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (26-MER), MAGNESIUM ION, ... | 著者 | Patel, A, Cheng, X. | 登録日 | 2017-03-07 | 公開日 | 2018-03-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.064 Å) | 主引用文献 | DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins. Cell, 173, 2018
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5UND
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7L4Y
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3KV4
| Structure of PHF8 in complex with histone H3 | 分子名称: | 1,2-ETHANEDIOL, FE (II) ION, Histone H3-like, ... | 著者 | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | 登録日 | 2009-11-29 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
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2ZO0
| mouse NP95 SRA domain DNA specific complex 1 | 分子名称: | DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), E3 ubiquitin-protein ligase UHRF1 | 著者 | Hashimoto, H, Horton, J.R, Cheng, X. | 登録日 | 2008-05-05 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix Nature, 455, 2008
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2ZO1
| Mouse NP95 SRA domain DNA specific complex 2 | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), ... | 著者 | Hashimoto, H, Horton, J.R, Cheng, X. | 登録日 | 2008-05-05 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix Nature, 455, 2008
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5EYO
| The crystal structure of the Max bHLH domain in complex with 5-carboxyl cytosine DNA | 分子名称: | DNA (5'-D(*AP*GP*TP*AP*GP*CP*AP*(1CC)P*GP*TP*GP*CP*TP*AP*CP*T)-3'), Protein max | 著者 | Wang, D, Hashimoto, H, Zhang, X, Cheng, X. | 登録日 | 2015-11-25 | 公開日 | 2016-12-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma. Nucleic Acids Res., 45, 2017
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1M0E
| ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASE | 分子名称: | 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(Z)P*GP*CP*AP*TP*GP*G)-3', Modification methylase HhaI, ... | 著者 | Zhou, L, Cheng, X, Connolly, B.A, Dickman, M.J, Hurd, P.J, Hornby, D.P. | 登録日 | 2002-06-12 | 公開日 | 2002-09-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASES J.MOL.BIOL., 321, 2002
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1ML9
| Structure of the Neurospora SET domain protein DIM-5, a histone lysine methyltransferase | 分子名称: | Histone H3 methyltransferase DIM-5, UNKNOWN, ZINC ION | 著者 | Zhang, X, Tamaru, H, Khan, S.I, Horton, J.R, Keefe, L.J, Selker, E.U, Cheng, X. | 登録日 | 2002-08-30 | 公開日 | 2002-10-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure of the Neurospora SET domain protein DIM-5,
a histone H3 lysine methyltransferase Cell(Cambridge,Mass.), 111, 2002
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4QW2
| FMRP N-terminal domain (R138Q) | 分子名称: | 1,2-ETHANEDIOL, Fragile X mental retardation protein 1, LEAD (II) ION | 著者 | Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T. | 登録日 | 2014-07-16 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.989 Å) | 主引用文献 | Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain. Hum.Mol.Genet., 24, 2015
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4QVZ
| FMRP N-terminal domain | 分子名称: | 1,2-ETHANEDIOL, Fragile X mental retardation protein 1 | 著者 | Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T. | 登録日 | 2014-07-16 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.195 Å) | 主引用文献 | Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain. Hum.Mol.Genet., 24, 2015
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1NGN
| Mismatch repair in methylated DNA. Structure of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4 | 分子名称: | methyl-CpG binding protein MBD4 | 著者 | Wu, P, Qiu, C, Sohail, A, Zhang, X, Bhagwat, A.S, Cheng, X. | 登録日 | 2002-12-17 | 公開日 | 2003-03-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4 J.Biol.Chem., 278, 2003
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4RTS
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4RNW
| Truncated version of the G303 Circular Permutation of Old Yellow Enzyme | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, ... | 著者 | Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S. | 登録日 | 2014-10-26 | 公開日 | 2015-01-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.552 Å) | 主引用文献 | STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME. ACS Catal, 5, 2015
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4RTR
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4RTO
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4RTJ
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4RTN
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4RTQ
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4RTM
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4RTP
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4RTK
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