7LMB
| Tetrahymena telomerase T5D5 structure at 3.8 Angstrom | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. | Deposit date: | 2021-02-05 | Release date: | 2021-05-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
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7LMA
| Tetrahymena telomerase T3D2 structure at 3.3 Angstrom | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. | Deposit date: | 2021-02-05 | Release date: | 2021-05-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
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4AIS
| A complex structure of BtGH84 | Descriptor: | GLYCEROL, GLYCOLIC ACID, O-GLCNACASE BT_4395 | Authors: | He, Y, Davies, G.J. | Deposit date: | 2012-02-13 | Release date: | 2012-06-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: Intracellular Beta-O-Linked N-Glycolylglucosamine (Glcngc), Udp-Glcngc, and the Biochemical and Structural Rationale for the Substrate Tolerance of Beta-O-Linked Beta-N-Acetylglucosaminidase. J.Biol.Chem., 287, 2012
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4AIU
| A complex structure of BtGH84 | Descriptor: | (3AR,5R,6S,7R,7AR)-2,5-BIS(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]OXAZOLE-6,7-DIOL, CALCIUM ION, O-GLCNACASE BT_4395 | Authors: | He, Y, Davies, G.J. | Deposit date: | 2012-02-13 | Release date: | 2012-06-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: Intracellular Beta-O-Linked N-Glycolylglucosamine (Glcngc), Udp-Glcngc, and the Biochemical and Structural Rationale for the Substrate Tolerance of Beta-O-Linked Beta-N-Acetylglucosaminidase. J.Biol.Chem., 287, 2012
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3K7I
| Crystal structure of the E131K mutant of the Indian Hedgehog N-terminal signalling domain | Descriptor: | Indian hedgehog protein, SULFATE ION, ZINC ION | Authors: | He, Y.-X, Kang, Y, Zhang, W.J, Yu, J, Ma, G, Zhou, C.-Z. | Deposit date: | 2009-10-13 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.438 Å) | Cite: | Crystal structure of the E131K mutant of the Indian Hedgehog N-terminal signalling domain To be Published
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3K7H
| Crystal structure of the E95K mutant of the Indian Hedgehog N-terminal signalling domain | Descriptor: | Indian hedgehog protein, SULFATE ION, ZINC ION | Authors: | He, Y.-X, Kang, Y, Zhang, W.J, Yu, J, Ma, G, Zhou, C.-Z. | Deposit date: | 2009-10-13 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the E95K mutant of the Indian Hedgehog N-terminal signalling domain To be Published
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3K7G
| Crystal structure of the Indian Hedgehog N-terminal signalling domain | Descriptor: | GLYCEROL, Indian hedgehog protein, SULFATE ION, ... | Authors: | He, Y.-X, Kang, Y, Zhang, W.J, Yu, J, Ma, G, Zhou, C.-Z. | Deposit date: | 2009-10-13 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the Indian Hedgehog N-terminal signalling domain To be Published
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3K7J
| Crystal structure of the D100E mutant of the Indian Hedgehog N-terminal signalling domain | Descriptor: | CARBONATE ION, Indian hedgehog protein, SULFATE ION, ... | Authors: | He, Y.-X, Kang, Y, Zhang, W.J, Yu, J, Ma, G, Zhou, C.-Z. | Deposit date: | 2009-10-13 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the D100E mutant of the Indian Hedgehog N-terminal signalling domain To be Published
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5I8Q
| S. cerevisiae Prp43 in complex with RNA and ADPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43, ... | Authors: | He, Y, Nielsen, K.H, Andersen, G.R. | Deposit date: | 2016-02-19 | Release date: | 2017-02-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA. RNA, 23, 2017
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2JU7
| Solution-State Structures of Oleate-Liganded LFABP, Protein Only | Descriptor: | Fatty acid-binding protein, liver | Authors: | He, Y, Yang, X, Wang, H, Estephan, R, Francis, F, Kodukula, S, Storch, J, Stark, R.E. | Deposit date: | 2007-08-15 | Release date: | 2007-11-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution-State Molecular Structure of Apo and Oleate-Liganded Liver Fatty Acid-Binding Protein Biochemistry, 46, 2007
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7LT3
| NHEJ Long-range synaptic complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (30-MER), DNA (31-MER), ... | Authors: | He, Y, Chen, S. | Deposit date: | 2021-02-18 | Release date: | 2021-04-14 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis of long-range to short-range synaptic transition in NHEJ. Nature, 593, 2021
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7LSY
| NHEJ Short-range synaptic complex | Descriptor: | DNA (26-MER), DNA (5'-D(P*CP*AP*AP*TP*GP*AP*AP*AP*CP*GP*GP*AP*AP*CP*AP*GP*TP*CP*AP*G)-3'), DNA (5'-D(P*GP*TP*TP*CP*TP*TP*AP*GP*TP*AP*TP*AP*TP*A)-3'), ... | Authors: | He, Y, Chen, S. | Deposit date: | 2021-02-18 | Release date: | 2021-04-14 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | Structural basis of long-range to short-range synaptic transition in NHEJ. Nature, 593, 2021
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2JU3
| Solution-state NMR structures of apo-LFABP (Liver Fatty Acid-Binding Protein) | Descriptor: | Fatty acid-binding protein, liver | Authors: | He, Y, Yang, X, Wang, H, Estephan, R, Francis, F, Kodukula, S, Storch, J, Stark, R.E. | Deposit date: | 2007-08-14 | Release date: | 2007-11-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution-State Molecular Structure of Apo and Oleate-Liganded Liver Fatty Acid-Binding Protein Biochemistry, 46, 2007
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1DGI
| Cryo-EM structure of human poliovirus(serotype 1)complexed with three domain CD155 | Descriptor: | POLIOVIRUS RECEPTOR, VP1, VP2, ... | Authors: | He, Y, Bowman, V.D, Mueller, S, Bator, C.M, Bella, J, Peng, X, Baker, T.S, Wimmer, E, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 1999-11-24 | Release date: | 2000-01-24 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (22 Å) | Cite: | Interaction of the poliovirus receptor with poliovirus. Proc.Natl.Acad.Sci.USA, 97, 2000
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2W66
| BtGH84 in complex with HQ602 | Descriptor: | CALCIUM ION, GLYCEROL, N-[(3R,4S,5R,6R,7R)-3,5,6-trihydroxy-7-(hydroxymethyl)azepan-4-yl]acetamide, ... | Authors: | He, Y, Davies, G.J. | Deposit date: | 2008-12-17 | Release date: | 2009-04-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Molecular Basis for Inhibition of Gh84 Glycoside Hydrolases by Substituted Azepanes: Conformational Flexibility Enables Probing of Substrate Distortion. J.Am.Chem.Soc., 131, 2009
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3SQJ
| Recombinant human serum albumin from transgenic plant | Descriptor: | MYRISTIC ACID, Serum albumin | Authors: | He, Y, Yang, D. | Deposit date: | 2011-07-05 | Release date: | 2011-11-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Large-scale production of functional human serum albumin from transgenic rice seeds. Proc.Natl.Acad.Sci.USA, 108, 2011
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2W67
| BtGH84 in complex with FMA34 | Descriptor: | CALCIUM ION, GLYCEROL, N-[(3S,4R,5R,6R)-4,5,6-trihydroxyazepan-3-yl]acetamide, ... | Authors: | He, Y, Davies, G.J. | Deposit date: | 2008-12-17 | Release date: | 2009-04-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Molecular Basis for Inhibition of Gh84 Glycoside Hydrolases by Substituted Azepanes: Conformational Flexibility Enables Probing of Substrate Distortion. J.Am.Chem.Soc., 131, 2009
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2XM1
| BtGH84 in complex with N-acetyl gluconolactam | Descriptor: | GLYCEROL, N-ACETYL GLUCONOLACTAM, O-GLCNACASE BT_4395 | Authors: | He, Y, Davies, G.J. | Deposit date: | 2010-07-22 | Release date: | 2011-08-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inhibition of a Bacterial O-Glcnacase Homologue by Lactone and Lactam Derivatives: Structural, Kinetic and Thermodynamic Analyses. Amino Acids, 40, 2011
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2XJ7
| BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine | Descriptor: | 6-ACETAMIDO-6-DEOXY-CASTANOSPERMINE, CALCIUM ION, O-GLCNACASE BT_4395 | Authors: | He, Y, Davies, G.J. | Deposit date: | 2010-07-02 | Release date: | 2010-09-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inhibition of O-Glcnacase Using a Potent and Cell-Permeable Inhibitor Does not Induce Insulin Resistance in 3T3-L1 Adipocytes. Chem.Biol., 17, 2010
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2APN
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2GA5
| yeast frataxin | Descriptor: | Frataxin homolog, mitochondrial | Authors: | He, Y, Alam, S.L, Proteasa, S.V, Zhang, Y, Lesuisse, E, Dancis, A. | Deposit date: | 2006-03-07 | Release date: | 2006-03-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Yeast Frataxin Solution Structure, Iron Binding and Ferrochelatase Interaction Biochemistry, 43, 2004
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4P6X
| Crystal Structure of cortisol-bound glucocorticoid receptor ligand binding domain | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, Glucocorticoid receptor, Nuclear receptor coactivator 2 | Authors: | He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E. | Deposit date: | 2014-03-25 | Release date: | 2014-04-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures and mechanism for the design of highly potent glucocorticoids. Cell Res., 24, 2014
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1JSP
| NMR Structure of CBP Bromodomain in complex with p53 peptide | Descriptor: | CREB-BINDING PROTEIN, tumor protein p53 | Authors: | He, Y, Mujtaba, S, Zeng, L, Yan, S, Zhou, M.-M. | Deposit date: | 2001-08-17 | Release date: | 2002-08-17 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation. Mol.Cell, 13, 2004
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1NN8
| CryoEM structure of poliovirus receptor bound to poliovirus | Descriptor: | MYRISTIC ACID, coat protein VP1, coat protein VP2, ... | Authors: | He, Y, Mueller, S, Chipman, P.R, Bator, C.M, Peng, X, Bowman, V.D, Mukhopadhyay, S, Wimmer, E, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2003-01-13 | Release date: | 2004-01-27 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (15 Å) | Cite: | Complexes of poliovirus serotypes with their common cellular receptor, CD155 J.Virol., 77, 2003
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2FS1
| solution structure of PSD-1 | Descriptor: | PSD-1 | Authors: | He, Y, Rozak, D.A, Sari, N, Chen, Y, Bryan, P, Orban, J. | Deposit date: | 2006-01-20 | Release date: | 2006-12-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure, dynamics, and stability variation in bacterial albumin binding modules: implications for species specificity. Biochemistry, 45, 2006
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