2W66
BtGH84 in complex with HQ602
Summary for 2W66
Entry DOI | 10.2210/pdb2w66/pdb |
Related | 2CHN 2CHO 2J47 2J4G 2JIW 2VVN 2VVS 2VW3 2W4X 2W67 |
Descriptor | O-GLCNACASE BT_4395, N-[(3R,4S,5R,6R,7R)-3,5,6-trihydroxy-7-(hydroxymethyl)azepan-4-yl]acetamide, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | glycoside hydrolase, complex, hydrolase, inhibitor, glycosidase |
Biological source | BACTEROIDES THETAIOTAOMICRON VPI-5482 |
Total number of polymer chains | 2 |
Total formula weight | 165365.06 |
Authors | He, Y.,Davies, G.J. (deposition date: 2008-12-17, release date: 2009-04-14, Last modification date: 2023-12-13) |
Primary citation | Marcelo, F.,He, Y.,Yuzwa, S.A.,Nieto, L.,Jimenez-Barbero, J.,Sollogoub, M.,Vocadlo, D.J.,Davies, G.J.,Bleriot, Y. Molecular Basis for Inhibition of Gh84 Glycoside Hydrolases by Substituted Azepanes: Conformational Flexibility Enables Probing of Substrate Distortion. J.Am.Chem.Soc., 131:5390-, 2009 Cited by PubMed: 19331390DOI: 10.1021/JA809776R PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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