5YB4
 
 | | Crystal structure of HP23LN36KR | | 分子名称: | HP23L, N36KR | | 著者 | Zhang, X, Wang, X, He, Y. | | 登録日 | 2017-09-03 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket
Front Cell Infect Microbiol, 8, 2018
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2VSN
 | | Structure and topological arrangement of an O-GlcNAc transferase homolog: insight into molecular control of intracellular glycosylation | | 分子名称: | URIDINE-5'-DIPHOSPHATE, XCOGT | | 著者 | Martinez-Fleites, C, Macauley, M.S, He, Y, Shen, D, Vocadlo, D, Davies, G.J. | | 登録日 | 2008-04-28 | | 公開日 | 2008-06-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure of an O-Glcnac Transferase Homolog Provides Insight Into Intracellular Glycosylation.
Nat.Struct.Mol.Biol., 15, 2008
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3F3H
 | | Crystal structure and anti-tumor activity of LZ-8 from the fungus Ganoderma lucidium | | 分子名称: | Immunomodulatory protein Ling Zhi-8 | | 著者 | Zhou, C.Z, Huang, L, He, Y.X, Bao, R, Sun, F, Liang, C, Liu, L. | | 登録日 | 2008-10-30 | | 公開日 | 2009-09-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of LZ-8 from the medicinal fungus Ganoderma lucidium
Proteins, 75, 2009
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8FFZ
 | | TFIIIA-TFIIIC-Brf1-TBP complex bound to 5S rRNA gene | | 分子名称: | DNA (151-MER), Transcription factor IIIA, Transcription factor IIIB 70 kDa subunit,TATA-box-binding protein, ... | | 著者 | Talyzina, A, He, Y. | | 登録日 | 2022-12-11 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation.
Mol.Cell, 83, 2023
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1PO5
 | | Structure of mammalian cytochrome P450 2B4 | | 分子名称: | Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Scott, E.E, He, Y.A, Wester, M.R, White, M.A, Chin, C.C, Halpert, J.R, Johnson, E.F, Stout, C.D. | | 登録日 | 2003-06-13 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | An open conformation of mammalian cytochrome P450 2B4 at 1.6 A resolution
Proc.Natl.Acad.Sci.USA, 100, 2003
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1IJG
 | | Structure of the Bacteriophage phi29 Head-Tail Connector Protein | | 分子名称: | UPPER COLLAR PROTEIN | | 著者 | Simpson, A.A, Leiman, P.G, Tao, Y, He, Y, Badasso, M, Jardine, P.J, Anderson, D.L, Rossmann, M.G. | | 登録日 | 2001-04-26 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure determination of the head-tail connector of bacteriophage phi29.
Acta Crystallogr.,Sect.D, 57, 2001
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3CMI
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6V85
 | | Parainfluenza virus 5 L-P complex | | 分子名称: | Phosphoprotein, RNA-directed RNA polymerase L, ZINC ION | | 著者 | Abdella, R, He, Y. | | 登録日 | 2019-12-10 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.38 Å) | | 主引用文献 | Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6V86
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1S17
 | | Identification of Novel Potent Bicyclic Peptide Deformylase Inhibitors | | 分子名称: | 2-(3,4-DIHYDRO-3-OXO-2H-BENZO[B][1,4]THIAZIN-2-YL)-N-HYDROXYACETAMIDE, GLYCEROL, NICKEL (II) ION, ... | | 著者 | Molteni, V, He, X, Nabakka, J, Yang, K, Kreusch, A, Gordon, P, Bursulaya, B, Ryder, N.S, Goldberg, R, He, Y. | | 登録日 | 2004-01-05 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Identification of novel potent bicyclic peptide deformylase inhibitors
Bioorg.Med.Chem.Lett., 14, 2004
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8K8H
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1JEW
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1XU4
 | | ATPASE IN COMPLEX WITH AMP-PNP, MAGNESIUM AND POTASSIUM CO-F | | 分子名称: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Wu, Y, Qian, X, He, Y, Moya, I.A, Luo, Y. | | 登録日 | 2004-10-25 | | 公開日 | 2004-11-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of an ATPase-active form of Rad51 homolog from Methanococcus voltae. Insights into potassium dependence
J.Biol.Chem., 280, 2005
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6O9M
 | | Structure of the human apo TFIIH | | 分子名称: | CDK-activating kinase assembly factor MAT1, General transcription factor IIH subunit 1, General transcription factor IIH subunit 2, ... | | 著者 | Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I. | | 登録日 | 2019-03-14 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
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3RN4
 | | Crystal structure of iron-substituted Sod2 from Saccharomyces cerevisiae | | 分子名称: | FE (III) ION, Superoxide dismutase [Mn], mitochondrial | | 著者 | Kang, Y, He, Y.-X, Cheng, W, Zhou, C.-Z, Li, W.-F. | | 登録日 | 2011-04-21 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structures of native and Fe-substituted SOD2 from Saccharomyces cerevisiae
Acta Crystallogr.,Sect.F, 67, 2011
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2B21
 | | RADA Recombinase in complex with AMPPNP at pH 6.0 | | 分子名称: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Qian, X, He, Y, Wu, Y, Luo, Y. | | 登録日 | 2005-09-16 | | 公開日 | 2006-08-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of Methanococcus Voltae Rada at an Acidic pH
To be Published
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6IUG
 | | Cryo-EM structure of the plant actin filaments from Zea mays pollen | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, pollen F-actin | | 著者 | Ren, Z.H, Zhang, Y, Zhang, Y, He, Y.Q, Du, P.Z, Wang, Z.X, Sun, F, Ren, H.Y. | | 登録日 | 2018-11-28 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM Structure of Actin Filaments fromZea maysPollen.
Plant Cell, 31, 2019
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8GAP
 | | Structure of LARP7 protein p65-telomerase RNA complex in telomerase | | 分子名称: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | | 著者 | Wang, Y, He, Y, Wang, Y, Yang, Y, Singh, M, Eichhorn, C.D, Zhou, Z.H, Feigon, J. | | 登録日 | 2023-02-23 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of LARP7 Protein p65-telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR.
J.Mol.Biol., 435, 2023
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7DV4
 | | Crystal structure of anti-CTLA-4 VH domain in complex with human CTLA-4 | | 分子名称: | 1,2-ETHANEDIOL, 4003-1(VH), Cytotoxic T-lymphocyte protein 4 | | 著者 | Li, H, Gan, X, He, Y. | | 登録日 | 2021-01-12 | | 公開日 | 2022-01-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | An anti-CTLA-4 heavy chain-only antibody with enhanced T reg depletion shows excellent preclinical efficacy and safety profile.
Proc.Natl.Acad.Sci.USA, 119, 2022
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5BXJ
 | | Complex of the Fk1 domain mutant A19T of FKBP51 with 4-Nitrophenol | | 分子名称: | P-NITROPHENOL, Peptidyl-prolyl cis-trans isomerase FKBP5 | | 著者 | Wu, D, Tao, X, Chen, Z, Han, J, Jia, W, Li, X, Wang, Z, He, Y.X. | | 登録日 | 2015-06-09 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells
J. Hazard. Mater., 307, 2016
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7ETT
 | | The FK1 domain of FKBP51 in complex with peptide-inhibitor hit QFPFV | | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit | | 著者 | Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J. | | 登録日 | 2021-05-14 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
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7ETV
 | | The FK1 domain of FKBP51 in complex with peptide-inhibitor hit DFPFV | | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit | | 著者 | Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J. | | 登録日 | 2021-05-14 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
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7ETU
 | | The FK1 domain of FKBP51 in complex with peptide-inhibitor hit SFPFT | | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit | | 著者 | Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J. | | 登録日 | 2021-05-14 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
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2MVT
 | | Solution structure of scoloptoxin SSD609 from Scolopendra mutilans | | 分子名称: | Scoloptoxin SSD609 | | 著者 | Wu, F, Sun, P, Wang, C, He, Y, Zhang, L, Tian, C. | | 登録日 | 2014-10-14 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A distinct three-helix centipede toxin SSD609 inhibits Iks channels by interacting with the KCNE1 auxiliary subunit.
Sci Rep, 5, 2015
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4J51
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