6XR0
 
 | | Crystal Structure of Human Melanotransferrin in complex with SC57.32 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, ... | | 著者 | Hayashi, K, Longenecker, K.L, Vivona, S. | | 登録日 | 2020-07-10 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.064 Å) | | 主引用文献 | Complex of human Melanotransferrin and SC57.32 Fab fragment reveals novel interdomain arrangement with ferric N-lobe and open C-lobe.
Sci Rep, 11, 2021
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3CV9
 | | Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R73A/R84A mutant) in complex with 1alpha,25-dihydroxyvitamin D3 | | 分子名称: | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Hayashi, K, Sugimoto, H, Shinkyo, R, Yamada, M, Ikeda, S, Ikushiro, S, Kamakura, M, Shiro, Y, Sakaki, T. | | 登録日 | 2008-04-18 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure-based design of a highly active vitamin D hydroxylase from Streptomyces griseolus CYP105A1
Biochemistry, 47, 2008
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3CV8
 | | Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84F mutant) | | 分子名称: | Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Hayashi, K, Sugimoto, H, Shinkyo, R, Yamada, M, Ikeda, S, Ikushiro, S, Kamakura, M, Shiro, Y, Sakaki, T. | | 登録日 | 2008-04-18 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-based design of a highly active vitamin D hydroxylase from Streptomyces griseolus CYP105A1
Biochemistry, 47, 2008
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6VGR
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6VGO
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2RM8
 | | The solution structure of phototactic transducer protein HtrII linker region from Natronomonas pharaonis | | 分子名称: | Sensory rhodopsin II transducer | | 著者 | Hayashi, K, Sudo, Y, Jee, J, Mishima, M, Hara, H, Kamo, N, Kojima, C. | | 登録日 | 2007-10-15 | | 公開日 | 2007-12-04 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Analysis of the Phototactic Transducer Protein HtrII Linker Region from Natronomonas pharaonis
Biochemistry, 46, 2007
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7EI2
 | | Structure of human NNMT in complex with macrocyclic peptide 8 | | 分子名称: | Nicotinamide N-methyltransferase, macrocyclic peptide 8 | | 著者 | Hayashi, K, Mikamiyama, H, Uehara, S, Yamamoto, S, Cary, D, Nishikawa, J, Ueda, T, Ozasa, H, Mihara, K, Yoshimura, N, Kawai, T, Ono, T, Yamamoto, S, Fumoto, M. | | 登録日 | 2021-03-30 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Macrocyclic Peptides as a Novel Class of NNMT Inhibitors: A SAR Study Aimed at Inhibitory Activity in the Cell.
Acs Med.Chem.Lett., 12, 2021
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7EHZ
 | | Structure of human NNMT in complex with macrocyclic peptide 2 | | 分子名称: | Nicotinamide N-methyltransferase, macrocyclic peptide 2 | | 著者 | Hayashi, K, Mikamiyama, H, Uehara, S, Yamamoto, S, Cary, D, Nishikawa, J, Ueda, T, Ozasa, H, Mihara, K, Yoshimura, N, Kawai, T, Ono, T, Yamamoto, S, Fumoto, M. | | 登録日 | 2021-03-30 | | 公開日 | 2021-12-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Macrocyclic Peptides as a Novel Class of NNMT Inhibitors: A SAR Study Aimed at Inhibitory Activity in the Cell.
Acs Med.Chem.Lett., 12, 2021
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7EGU
 | | Structure of human NNMT in complex with macrocyclic peptide X | | 分子名称: | Nicotinamide N-methyltransferase, macrocyclic peptide X | | 著者 | Hayashi, K, Mikamiyama, H, Uehara, S, Yamamoto, S, Cary, D, Nishikawa, J, Ueda, T, Ozasa, H, Mihara, K, Yoshimura, N, Kawai, T, Ono, T, Yamamoto, S, Fumoto, M. | | 登録日 | 2021-03-26 | | 公開日 | 2021-12-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Macrocyclic Peptides as a Novel Class of NNMT Inhibitors: A SAR Study Aimed at Inhibitory Activity in the Cell.
Acs Med.Chem.Lett., 12, 2021
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5X7E
 | | Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84A mutant) in complex with 1,25-dihydroxyvitamin D2 | | 分子名称: | (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-5,6-dimethyl-6-oxidanyl-hept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydr o-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, PROTOPORPHYRIN IX CONTAINING FE, Vitamin D3 dihydroxylase | | 著者 | Hayashi, K, Yasuda, K, Shiro, Y, Sugimoto, H, Sakaki, T. | | 登録日 | 2017-02-25 | | 公開日 | 2017-05-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Production of an active form of vitamin D2 by genetically engineered CYP105A1
Biochem. Biophys. Res. Commun., 486, 2017
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3C6N
 | | Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling | | 分子名称: | (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ... | | 著者 | Tan, X, Zheng, N, Hayashi, K. | | 登録日 | 2008-02-04 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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7YF6
 | | Crystal structure of HIV-1 protease in complex with macrocyclic peptide | | 分子名称: | MAGNESIUM ION, Macrocyclic Peptide, Protease | | 著者 | Kusumoto, Y, Sato, S, Yamada, T, Kozono, I, Nakata, Z, Asada, N, Mitsuki, S, Wakasa-Morimoto, C, Tohru, M, Watanabe, A, Hayashi, K, Mikamiyama, H. | | 登録日 | 2022-07-07 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Highly Potent and Oral Macrocyclic Peptides as a HIV-1 Protease Inhibitor: mRNA Display-Derived Hit-to-Lead Optimization.
Acs Med.Chem.Lett., 13, 2022
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3RI9
 | | Xylanase C from Aspergillus kawachii F131W mutant | | 分子名称: | Endo-1,4-beta-xylanase 3 | | 著者 | Fushinobu, S, Uno, T, Kitaoka, M, Hayashi, K, Matsuzawa, H, Wakagi, T. | | 登録日 | 2011-04-13 | | 公開日 | 2011-09-21 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mutational analysis of fungal family 11 xylanases on pH optimum determination
J.APPL.GLYOSCI., 58, 2011
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3RI8
 | | Xylanase C from Aspergillus kawachii D37N mutant | | 分子名称: | Endo-1,4-beta-xylanase 3 | | 著者 | Fushinobu, S, Uno, T, Kitaoka, M, Hayashi, K, Matsuzawa, H, Wakagi, T. | | 登録日 | 2011-04-13 | | 公開日 | 2011-10-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mutational analysis of fungal family 11 xylanases on pH optimum determination
J.APPL.GLYOSCI., 58, 2011
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3W9I
 | | Structural basis for the inhibition of bacterial multidrug exporters | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Multidrug resistance protein MexB | | 著者 | Sakurai, K, Nakashima, R, Hayashi, K, Yamaguchi, A. | | 登録日 | 2013-04-04 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
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3W9J
 | | Structural basis for the inhibition of bacterial multidrug exporters | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Multidrug resistance protein MexB, [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | | 著者 | Sakurai, K, Nakashima, R, Hayashi, K, Yamaguchi, A. | | 登録日 | 2013-04-04 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
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1V7V
 | | Crystal structure of Vibrio proteolyticus chitobiose phosphorylase | | 分子名称: | CALCIUM ION, chitobiose phosphorylase | | 著者 | Hidaka, M, Honda, Y, Nirasawa, S, Kitaoka, M, Hayashi, K, Wakagi, T, Shoun, H, Fushinobu, S. | | 登録日 | 2003-12-24 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Chitobiose phosphorylase from Vibrio proteolyticus, a member of glycosyl transferase family 36, has a clan GH-L-like (alpha/alpha)(6) barrel fold.
Structure, 12, 2004
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1V7W
 | | Crystal structure of Vibrio proteolyticus chitobiose phosphorylase in complex with GlcNAc | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Hidaka, M, Honda, Y, Nirasawa, S, Kitaoka, M, Hayashi, K, Wakagi, T, Shoun, H, Fushinobu, S. | | 登録日 | 2003-12-24 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Chitobiose phosphorylase from Vibrio proteolyticus, a member of glycosyl transferase family 36, has a clan GH-L-like (alpha/alpha)(6) barrel fold.
Structure, 12, 2004
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1V7X
 | | Crystal structure of Vibrio proteolyticus chitobiose phosphorylase in complex with GlcNAc and sulfate | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Hidaka, M, Honda, Y, Nirasawa, S, Kitaoka, M, Hayashi, K, Wakagi, T, Shoun, H, Fushinobu, S. | | 登録日 | 2003-12-24 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Chitobiose phosphorylase from Vibrio proteolyticus, a member of glycosyl transferase family 36, has a clan GH-L-like (alpha/alpha)(6) barrel fold.
Structure, 12, 2004
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5YIL
 | | Hoisting-loop in bacterial multidrug exporter AcrB is a highly flexible hinge that enables the large motion of the subdomains | | 分子名称: | Multidrug efflux pump subunit AcrB | | 著者 | Zwama, M, Sakurai, K, Hayashi, K, Nakashima, R, Kitagawa, K, Nishino, K, Yamaguchi, A. | | 登録日 | 2017-10-05 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Hoisting-Loop in Bacterial Multidrug Exporter AcrB Is a Highly Flexible Hinge That Enables the Large Motion of the Subdomains.
Front Microbiol, 8, 2017
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3AXY
 | | Structure of Florigen Activation Complex Consisting of Rice Florigen Hd3a, 14-3-3 Protein GF14 and Rice FD Homolog OsFD1 | | 分子名称: | 14-3-3-like protein GF14-C, Protein HEADING DATE 3A, Rice FD homolog OsFD1 | | 著者 | Ohki, I, Furuita, K, Hayashi, K, Taoka, K, Tsuji, H, Nakagawa, A, Shimamoto, K, Kojima, C. | | 登録日 | 2011-04-19 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 14-3-3 proteins act as intracellular receptors for rice Hd3a florigen
Nature, 476, 2011
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2DEP
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3A8R
 | | The structure of the N-terminal regulatory domain of a plant NADPH oxidase | | 分子名称: | CALCIUM ION, Putative uncharacterized protein | | 著者 | Oda, T, Hashimoto, H, Kuwabara, N, Akashi, S, Hayashi, K, Kojima, C, Wong, H.L, Kawasaki, T, Shimamoto, K, Sato, M, Shimizu, T. | | 登録日 | 2009-10-07 | | 公開日 | 2009-10-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structure of the N-terminal regulatory domain of a plant NADPH oxidase and its functional implications
J.Biol.Chem., 285, 2010
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2ZBY
 | | Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84A mutant) | | 分子名称: | Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. | | 登録日 | 2007-10-30 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3
Biochemistry, 47, 2008
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2ZBZ
 | | Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84A mutant) in complex with 1,25-dihydroxyvitamin D3 | | 分子名称: | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. | | 登録日 | 2007-10-30 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3
Biochemistry, 47, 2008
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