6VGR

Crystal Structure of Human Dipeptidase 3 in Complex with Fab of SC-003

Summary for 6VGR

Entry DOI	10.2210/pdb6vgr/pdb
Descriptor	Dipeptidase 3, SC-003 Fab Heavy Chain, SC-003 Fab Light Chain, ... (4 entities in total)
Functional Keywords	fab, antibody drug conjugate, dipeptidase, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	203286.86
Authors	Hayashi, K.,Longenecker, K.L.,Vivona, S. (deposition date: 2020-01-08, release date: 2020-05-13, Last modification date: 2023-10-11)
Primary citation	Hayashi, K.,Longenecker, K.L.,Koenig, P.,Prashar, A.,Hampl, J.,Stoll, V.,Vivona, S. Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity. J.Struct.Biol., 211:107512-107512, 2020 Cited by PubMed: 32325220 DOI: 10.1016/j.jsb.2020.107512 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.84 Å)

Structure validation