2V50
 
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2J8S
 | | Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors | | Descriptor: | ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-ALPHA-D-MALTOSIDE, ... | | Authors: | Sennhauser, G, Amstutz, P, Briand, C, Storchenegger, O, Gruetter, M.G. | | Deposit date: | 2006-10-27 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Drug Export Pathway of Multidrug Exporter Acrb Revealed by Darpin Inhibitors.
Plos Biol., 5, 2007
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3PCQ
 | | Femtosecond X-ray protein Nanocrystallography | | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | | Authors: | Chapman, H.N, Fromme, P, Barty, A, White, T.A, Kirian, R.A, Aquila, A, Hunter, M.S, Schulz, J, Deponte, D.P, Weierstall, U, Doak, R.B, Maia, F.R.N.C, Martin, A.V, Schlichting, I, Lomb, L, Coppola, N, Shoeman, R.L, Epp, S.W, Hartmann, R, Rolles, D, Rudenko, A, Foucar, L, Kimmel, N, Weidenspointner, G, Holl, P, Liang, M, Barthelmess, M, Caleman, C, Boutet, S, Bogan, M.J, Krzywinski, J, Bostedt, C, Bajt, S, Gumprecht, L, Rudek, B, Erk, B, Schmidt, C, Homke, A, Reich, C, Pietschner, D, Struder, L, Hauser, G, Gorke, H, Ullrich, J, Herrmann, S, Schaller, G, Schopper, F, Soltau, H, Kuhnel, K.-U, Messerschmidt, M, Bozek, J.D, Hau-Riege, S.P, Frank, M, Hampton, C.Y, Sierra, R, Starodub, D, Williams, G.J, Hajdu, J, Timneanu, N, Seibert, M.M, Andreasson, J, Rocker, A, Jonsson, O, Svenda, M, Stern, S, Nass, K, Andritschke, R, Schroter, C.-D, Krasniqi, F, Bott, M, Schmidt, K.E, Wang, X, Grotjohann, I, Holton, J.M, Barends, T.R.M, Neutze, R, Marchesini, S, Fromme, R, Schorb, S, Rupp, D, Adolph, M, Gorkhover, T, Andersson, I, Hirsemann, H, Potdevin, G, Graafsma, H, Nilsson, B, Spence, J.C.H. | | Deposit date: | 2010-10-21 | | Release date: | 2011-02-02 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (8.984 Å) | | Cite: | Femtosecond X-ray protein nanocrystallography.
Nature, 470, 2011
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4AC5
 | | Lipidic sponge phase crystal structure of the Bl. viridis reaction centre solved using serial femtosecond crystallography | | Descriptor: | 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ... | | Authors: | Johansson, L.C, Arnlund, D, White, T.A, Katona, G, DePonte, D.P, Weierstall, U, Doak, R.B, Shoeman, R.L, Lomb, L, Malmerberg, E, Davidsson, J, Nass, K, Liang, M, Andreasson, J, Aquila, A, Bajt, S, Barthelmess, M, Barty, A, Bogan, M.J, Bostedt, C, Bozek, J.D, Caleman, C, Coffee, R, Coppola, N, Ekeberg, T, Epp, S.W, Erk, B, Fleckenstein, H, Foucar, L, Graafsma, H, Gumprecht, L, Hajdu, J, Hampton, C.Y, Hartmann, R, Hartmann, A, Hauser, G, Hirsemann, H, Holl, P, Hunter, M.S, Kassemeyer, S, Kimmel, N, Kirian, R.A, Maia, F.R.N.C, Marchesini, S, Martin, A.V, Reich, C, Rolles, D, Rudek, B, Rudenko, A, Schlichting, I, Schulz, J, Seibert, M.M, Sierra, R, Soltau, H, Starodub, D, Stellato, F, Stern, S, Struder, L, Timneanu, N, Ullrich, J, Wahlgren, W.Y, Wang, X, Weidenspointner, G, Wunderer, C, Fromme, P, Chapman, H.N, Spence, J.C.H, Neutze, R. | | Deposit date: | 2011-12-14 | | Release date: | 2012-02-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (8.2 Å) | | Cite: | Lipidic Phase Membrane Protein Serial Femtosecond Crystallography.
Nat.Methods, 9, 2012
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6W25
 | | Crystal structure of the Melanocortin-4 Receptor (MC4R) in complex with SHU9119 | | Descriptor: | CALCIUM ION, Melanocortin receptor 4,GlgA glycogen synthase,Melanocortin receptor 4, OLEIC ACID, ... | | Authors: | Yu, J, Gimenez, L.E, Hernandez, C.C, Wu, Y, Wein, A.H, Han, G.W, McClary, K, Mittal, S.R, Burdsall, K, Stauch, B, Wu, L, Stevens, S.N, Peisley, A, Williams, S.Y, Chen, V, Millhauser, G.L, Zhao, S, Cone, R.D, Stevens, R.C. | | Deposit date: | 2020-03-04 | | Release date: | 2020-04-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Determination of the melanocortin-4 receptor structure identifies Ca2+as a cofactor for ligand binding.
Science, 368, 2020
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1Y7J
 | | NMR structure family of Human Agouti Signalling Protein (80-132: Q115Y, S124Y) | | Descriptor: | Agouti Signaling Protein | | Authors: | McNulty, J.C, Jackson, P.J, Thompson, D.A, Chai, B, Gantz, I, Barsh, G.S, Dawson, P.E, Millhauser, G.L. | | Deposit date: | 2004-12-08 | | Release date: | 2005-02-15 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Structures of the agouti signaling protein.
J.Mol.Biol., 346, 2005
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1Y7K
 | | NMR structure family of Human Agouti Signalling Protein (80-132: Q115Y, S124Y) | | Descriptor: | Agouti Signaling Protein | | Authors: | McNulty, J.C, Jackson, P.J, Thompson, D.A, Chai, B, Gantz, I, Barsh, G.S, Dawson, P.E, Millhauser, G.L. | | Deposit date: | 2004-12-08 | | Release date: | 2005-02-15 | | Last modified: | 2021-10-20 | | Method: | SOLUTION NMR | | Cite: | Structures of the agouti signaling protein.
J.Mol.Biol., 346, 2005
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1MR0
 | | SOLUTION NMR STRUCTURE OF AGRP(87-120; C105A) | | Descriptor: | AGOUTI RELATED PROTEIN | | Authors: | Jackson, P.J, Mcnulty, J.C, Yang, Y.K, Thompson, D.A, Chai, B, Gantz, I, Barsh, G.S, Millhauser, G.M. | | Deposit date: | 2002-09-17 | | Release date: | 2002-10-02 | | Last modified: | 2024-10-09 | | Method: | SOLUTION NMR | | Cite: | Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity.
Biochemistry, 41, 2002
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1HYK
 | | AGOUTI-RELATED PROTEIN (87-132) (AC-AGRP(87-132)) | | Descriptor: | AGOUTI RELATED PROTEIN | | Authors: | Bolin, K.A, Anderson, D.J, Trulson, J.A, Thompson, D.A, Wilken, J, Kent, S.B.H, Millhauser, G.L. | | Deposit date: | 2001-01-19 | | Release date: | 2001-02-07 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | NMR structure of a minimized human agouti related protein prepared by total chemical synthesis.
FEBS Lett., 451, 1999
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2L1J
 | | 1H assignments for ASIP(93-126, P103A, P105A, P111A, Q115Y, S124Y) | | Descriptor: | Agouti-signaling protein | | Authors: | Patel, M.P, Cribb Fabersunne, C.S, Yang, Y, Kaelin, C.B, Barsh, G.S, Millhauser, G.L. | | Deposit date: | 2010-07-28 | | Release date: | 2010-09-01 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Loop-swapped chimeras of the agouti-related protein and the agouti signaling protein identify contacts required for melanocortin 1 receptor selectivity and antagonism.
J.Mol.Biol., 404, 2010
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2KZA
 | | Solution structure of ASIP(80-132, P103A, P105A, Q115Y, S124Y) | | Descriptor: | Agouti-signaling protein | | Authors: | Patel, M.P, Cribb Fabersunne, C.S, Yang, Y, Kaelin, C.B, Barsh, G.S, Millhauser, G.L. | | Deposit date: | 2010-06-14 | | Release date: | 2010-07-21 | | Last modified: | 2020-02-05 | | Method: | SOLUTION NMR | | Cite: | Loop-swapped chimeras of the agouti-related protein and the agouti signaling protein identify contacts required for melanocortin 1 receptor selectivity and antagonism.
J.Mol.Biol., 404, 2010
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