2KZA
Solution structure of ASIP(80-132, P103A, P105A, Q115Y, S124Y)
Summary for 2KZA
| Entry DOI | 10.2210/pdb2kza/pdb |
| Related | 1HYK 1MR0 1Y7J 1Y7K |
| NMR Information | BMRB: 17001 |
| Descriptor | Agouti-signaling protein (1 entity in total) |
| Functional Keywords | agouti signaling protein, agouti related protein, melanocortin receptor 1, melanocortin receptor 4, mc1r, mc4r, agrp, asip, proline-switching, signaling protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 5771.92 |
| Authors | Patel, M.P.,Cribb Fabersunne, C.S.,Yang, Y.,Kaelin, C.B.,Barsh, G.S.,Millhauser, G.L. (deposition date: 2010-06-14, release date: 2010-07-21, Last modification date: 2020-02-05) |
| Primary citation | Patel, M.P.,Cribb Fabersunne, C.S.,Yang, Y.K.,Kaelin, C.B.,Barsh, G.S.,Millhauser, G.L. Loop-swapped chimeras of the agouti-related protein and the agouti signaling protein identify contacts required for melanocortin 1 receptor selectivity and antagonism. J.Mol.Biol., 404:45-55, 2010 Cited by PubMed: 20831872DOI: 10.1016/j.jmb.2010.08.054 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
Download full validation report
