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PDB: 106 件

1HA0
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HEMAGGLUTININ PRECURSOR HA0
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ PRECURSOR), alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, J, Ho Lee, K, Steinhauer, D.A, Stevens, D.J, Skehel, J.J, Wiley, D.C.
登録日1998-10-08
公開日1998-10-12
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation.
Cell(Cambridge,Mass.), 95, 1998
1RVX
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1934 H1 Hemagglutinin in complex with LSTA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gamblin, S.J, Haire, L.F, Russell, R.J, Stevens, D.J, Xiao, B, Ha, Y, Vasisht, N, Steinhauer, D.A, Daniels, R.S, Elliot, A, Wiley, D.C, Skehel, J.J.
登録日2003-12-15
公開日2004-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1RVT
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1930 H1 Hemagglutinin in complex with LSTC
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ...
著者Skehel, J.J, Gamblin, S.J, Haire, L.F, Russell, R.J, Stevens, D.J, Xiao, B, Ha, Y, Vasisht, N, Steinhauer, D.A, Daniels, R.S.
登録日2003-12-15
公開日2004-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
4JEU
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Crystal Structure of Munc18a and Syntaxin1 with native N-terminus complex
分子名称: Syntaxin-1A, Syntaxin-binding protein 1
著者Colbert, K.N, Hattendorf, D.A, Weiss, T.M, Burkhardt, P, Fasshauer, D, Weis, W.I.
登録日2013-02-27
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation.
Proc.Natl.Acad.Sci.USA, 110, 2013
7MLA
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Solution NMR structure of HDMX in complex with Zn and MCo-52-2
分子名称: MCo-52-2, Protein Mdm4, ZINC ION
著者Ramirez, L.S, Theophall, G, Chaudhuri, D, Camarero, J.C, Shekhtman, A.
登録日2021-04-28
公開日2022-05-04
実験手法SOLUTION NMR
主引用文献Solution NMR structure of HDMX in complex with Zn and cyclotide 52-2
To Be Published
1RVZ
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1934 H1 Hemagglutinin in complex with LSTC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
著者Gamblin, S.J, Haire, L.F, Russell, R.J, Stevens, D.J, Xiao, B, Ha, Y, Vasisht, N, Steinhauer, D.A, Daniels, R.S, Elliot, A, Wiley, D.C, Skehel, J.J.
登録日2003-12-15
公開日2004-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
3HGJ
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Old Yellow Enzyme from Thermus scotoductus SA-01 complexed with p-hydroxy-benzaldehyde
分子名称: Chromate reductase, FLAVIN MONONUCLEOTIDE, P-HYDROXYBENZALDEHYDE
著者Opperman, D.J, Sewell, B.T, Litthauer, D, Isupov, M.N, Littlechild, J.A, van Heerden, E.
登録日2009-05-14
公開日2010-02-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a thermostable old yellow enzyme from Thermus scotoductus SA-01
Biochem.Biophys.Res.Commun., 393, 2010
2FB8
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Structure of the B-Raf kinase domain bound to SB-590885
分子名称: (1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIME, B-Raf proto-oncogene serine/threonine-protein kinase
著者Lougheed, J.C, Lee, J, Chau, D.C, Stout, T.J.
登録日2005-12-08
公開日2006-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885.
Cancer Res., 66, 2006
6AT9
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Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-A*0101
分子名称: ALK, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G.
登録日2017-08-28
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9503 Å)
主引用文献A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Front Immunol, 9, 2018
1RUZ
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1918 H1 Hemagglutinin
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
著者Skehel, J.J, Gamblin, S.J, Haire, L.F, Russell, R.J, Stevens, D.J, Xiao, B, Ha, Y, Vasisht, N, Steinhauer, D.A, Daniels, R.S.
登録日2003-12-12
公開日2004-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1RV0
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1930 Swine H1 Hemagglutinin complexed with LSTA
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-alpha-D-glucopyranose, hemagglutinin
著者Skehel, J.J, Gamblin, S.J, Haire, L.F, Russell, R.J, Stevens, D.J, Xiao, B, Ha, Y, Vasisht, N, Steinhauer, D.A, Daniels, R.S.
登録日2003-12-12
公開日2004-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1RUY
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1930 Swine H1 Hemagglutinin
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
著者Skehel, J.J, Gamblin, S.J, Haire, L.F, Russell, R.J, Stevens, D.J, Xiao, B, Ha, Y, Vasisht, N, Steinhauer, D.A, Daniels, R.S.
登録日2003-12-12
公開日2004-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1XC5
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Solution Structure of the SMRT Deacetylase Activation Domain
分子名称: Nuclear receptor corepressor 2
著者Codina, A, Love, J.D, Li, Y, Lazar, M.A, Neuhaus, D, Schwabe, J.W.R.
登録日2004-09-01
公開日2005-05-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors
Proc.Natl.Acad.Sci.Usa, 102, 2005
3HF3
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BU of 3hf3 by Molmil
Old Yellow Enzyme from Thermus scotoductus SA-01
分子名称: Chromate reductase, FLAVIN MONONUCLEOTIDE, SULFATE ION
著者Opperman, D.J, Sewell, B.T, Litthauer, D, Isupov, M.N, Littlechild, J.A, van Heerden, E.
登録日2009-05-11
公開日2010-02-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a thermostable old yellow enzyme from Thermus scotoductus SA-01
Biochem.Biophys.Res.Commun., 393, 2010
1E7J
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HMG-D complexed to a bulge DNA
分子名称: DNA (5'-D(*CP*GP*AP*TP*AP*TP*TP*AP*AP*GP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*CP*AP*AP*TP*AP*TP*CP*G)-3'), HIGH MOBILITY GROUP PROTEIN D
著者Cerdan, R, Payet, D, Yang, J.-C, Travers, A.A, Neuhaus, D.
登録日2000-08-29
公開日2001-03-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Hmg-D Complexed to a Bulge DNA: An NMR Model
Protein Sci., 10, 2001
3EYK
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Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion
分子名称: 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
著者Russell, R.J, Kerry, P.S, Stevens, D.J, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J.
登録日2008-10-21
公開日2009-01-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
2YOA
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Synaptotagmin-1 C2B domain with phosphoserine
分子名称: CALCIUM ION, PHOSPHOSERINE, SYNAPTOTAGMIN-1, ...
著者Honigmann, A, van den Bogaart, G, Iraheta, E, Risselada, H.J, Milovanovic, D, Mueller, V, Muellar, S, Diederichsen, U, Fasshauer, D, Grubmuller, H, Hell, S.W, Eggeling, C, Kuhnel, K, Jahn, R.
登録日2012-10-22
公開日2013-03-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Phosphatidylinositol 4,5-Bisphosphate Clusters Act as Molecular Beacons for Vesicle Recruitment
Nat.Struct.Mol.Biol., 20, 2013
1HMA
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THE SOLUTION STRUCTURE AND DYNAMICS OF THE DNA BINDING DOMAIN OF HMG-D FROM DROSOPHILA MELANOGASTER
分子名称: HMG-D
著者Jones, D.N.M, Searles, M.A, Shaw, G.L, Churchill, M.E.A, Ner, S.S, Keeler, J, Travers, A.A, Neuhaus, D.
登録日1994-05-12
公開日1994-07-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure and dynamics of the DNA-binding domain of HMG-D from Drosophila melanogaster.
Structure, 2, 1994
1DZ5
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The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein
分子名称: PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
著者Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G.
登録日2000-02-16
公開日2000-03-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein
Nat.Struct.Biol., 7, 2000
1CDR
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STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CD59
著者Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D.
登録日1994-06-01
公開日1994-09-30
最終更新日2020-07-29
実験手法SOLUTION NMR
主引用文献Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
1CDS
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STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD59
著者Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D.
登録日1994-06-01
公開日1994-09-30
最終更新日2020-07-29
実験手法SOLUTION NMR
主引用文献Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
1HCP
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DNA RECOGNITION BY THE OESTROGEN RECEPTOR: FROM SOLUTION TO THE CRYSTAL
分子名称: HUMAN/CHICKEN ESTROGEN RECEPTOR, ZINC ION
著者Schwabe, J.W.R, Rhodes, D, Neuhaus, D.
登録日1993-11-23
公開日1995-11-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献DNA recognition by the oestrogen receptor: from solution to the crystal.
Structure, 1, 1993
1URQ
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Crystal structure of neuronal Q-SNAREs in complex with R-SNARE motif of Tomosyn
分子名称: M-TOMOSYN ISOFORM, SYNAPTOSOMAL-ASSOCIATED PROTEIN 25, SYNTAXIN 1A
著者Pobbati, A, Razeto, A, Becker, S, Fasshauer, D.
登録日2003-10-31
公開日2004-08-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Inhibitory Role of Tomosyn in Exocytosis
J.Biol.Chem., 279, 2004
2XHE
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Crystal structure of the Unc18-syntaxin 1 complex from Monosiga brevicollis
分子名称: SYNTAXIN1, UNC18
著者Burkhardt, P, Stegmann, C.M, Wahl, M.C, Fasshauer, D.
登録日2010-06-14
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Primordial Neurosecretory Apparatus Identified in the Choanoflagellate Monosiga Brevicollis.
Proc.Natl.Acad.Sci.USA, 108, 2011
1XJR
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The Structure of a Rigorously Conserved RNA Element Within the SARS Virus Genome
分子名称: MAGNESIUM ION, s2m RNA
著者Robertson, M.P, Igel, H, Baertsch, R, Haussler, D, Ares Jr, M, Scott, W.G.
登録日2004-09-24
公開日2005-02-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of a rigorously conserved RNA element within the SARS virus genome
Plos Biol., 3, 2005

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