Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 49 results

9HVP
DownloadVisualize
BU of 9hvp by Molmil
Design, activity and 2.8 Angstroms crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease
Descriptor: HIV-1 Protease, benzyl [(1R,4S,6S,9R)-4,6-dibenzyl-5-hydroxy-1,9-bis(1-methylethyl)-2,8,11-trioxo-13-phenyl-12-oxa-3,7,10-triazatridec-1-yl]carbamate
Authors:Neidhart, D.J, Erickson, J.
Deposit date:1990-11-06
Release date:1992-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease.
Science, 249, 1990
1MNS
DownloadVisualize
BU of 1mns by Molmil
ON THE ROLE OF LYSINE 166 IN THE MECHANISM OF MANDELATE RACEMASE FROM PSEUDOMONAS PUTIDA: MECHANISTIC AND CRYSTALLOGRAPHIC EVIDENCE FOR STEREOSPECIFIC ALKYLATION BY (R)-ALPHA-PHENYLGLYCIDATE
Descriptor: ATROLACTIC ACID (2-PHENYL-LACTIC ACID), MAGNESIUM ION, MANDELATE RACEMASE
Authors:Neidhart, D.J, Landro, J.A, Kozarich, J.W.
Deposit date:1993-07-06
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of lysine 166 in the mechanism of mandelate racemase from Pseudomonas putida: mechanistic and crystallographic evidence for stereospecific alkylation by (R)-alpha-phenylglycidate.
Biochemistry, 33, 1994
1SBC
DownloadVisualize
BU of 1sbc by Molmil
THE REFINED CRYSTAL STRUCTURE OF SUBTILISIN CARLSBERG AT 2.5 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, SUBTILISIN CARLSBERG
Authors:Neidhart, D.J, Petsko, G.A.
Deposit date:1988-05-13
Release date:1988-07-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The refined crystal structure of subtilisin Carlsberg at 2.5 A resolution.
Protein Eng., 2, 1988
1GG6
DownloadVisualize
BU of 1gg6 by Molmil
CRYSTAL STRUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL-PHENYLALANINE TRIFLUOROMETHYL KETONE BOUND AT THE ACTIVE SITE
Descriptor: 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE), 1,2-ETHANEDIOL, GAMMA CHYMOTRYPSIN, ...
Authors:Neidhart, D, Wei, Y, Cassidy, C, Lin, J, Cleland, W.W, Frey, P.A.
Deposit date:2000-07-31
Release date:2000-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Correlation of low-barrier hydrogen bonding and oxyanion binding in transition state analogue complexes of chymotrypsin.
Biochemistry, 40, 2001
1GGD
DownloadVisualize
BU of 1ggd by Molmil
CRYSTAL STRUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL-LEUCIL-PHENYLALANINE ALDEHYDE BOUND AT THE ACTIVE SITE
Descriptor: 2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE, GAMMA CHYMOTRYPSIN, SULFATE ION
Authors:Neidhart, D, Wei, Y, Cassidy, C, Lin, J, Cleland, W.W, Frey, P.A.
Deposit date:2000-08-14
Release date:2000-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Correlation of low-barrier hydrogen bonding and oxyanion binding in transition state analogue complexes of chymotrypsin.
Biochemistry, 40, 2000
2MNR
DownloadVisualize
BU of 2mnr by Molmil
MECHANISM OF THE REACTION CATALYZED BY MANDELATE RACEMASE. 2. CRYSTAL STRUCTURE OF MANDELATE RACEMASE AT 2.5 ANGSTROMS RESOLUTION: IDENTIFICATION OF THE ACTIVE SITE AND POSSIBLE CATALYTIC RESIDUES
Descriptor: MANDELATE RACEMASE, MANGANESE (II) ION, SULFATE ION
Authors:Neidhart, D.J, Petsko, G.A.
Deposit date:1993-07-06
Release date:1994-01-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of the reaction catalyzed by mandelate racemase. 2. Crystal structure of mandelate racemase at 2.5-A resolution: identification of the active site and possible catalytic residues.
Biochemistry, 30, 1991
5FMM
DownloadVisualize
BU of 5fmm by Molmil
crystal structure of the mid, cap-binding, mid-link and 627 domains from avian influenza a virus polymerase PB2 subunit bound to M7GTP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, CITRATE ANION, INFLUENZA A PB2 SUBUNIT
Authors:Thierry, E, Pflug, A, Hart, D, Cusack, S.
Deposit date:2015-11-06
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains.
Mol.Cell, 61, 2016
2VY6
DownloadVisualize
BU of 2vy6 by Molmil
Two domains from the C-terminal region of influenza A virus polymerase PB2 subunit
Descriptor: POLYMERASE BASIC PROTEIN 2
Authors:Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D.
Deposit date:2008-07-18
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit
Plos Pathog., 4, 2008
5FMQ
DownloadVisualize
BU of 5fmq by Molmil
Crystal structure of the mid, cap-binding, mid-link and 627 domains from avian influenza A virus polymerase PB2 subunit bound to M7GTP H32 crystal form
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, INFLUENZA A PB2 SUBUNIT
Authors:Thierry, E, Pflug, A, Hart, D, Cusack, S.
Deposit date:2015-11-07
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains.
Mol.Cell, 61, 2016
2GMO
DownloadVisualize
BU of 2gmo by Molmil
NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2
Descriptor: Polymerase basic protein 2
Authors:Boudet, J, Tarendeau, F, Guilligay, D, Mas, P, Bougault, C.M, Cusack, S, Simorre, J.-P, Hart, D.J.
Deposit date:2006-04-07
Release date:2007-02-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.
Nat.Struct.Mol.Biol., 14, 2007
3TJ3
DownloadVisualize
BU of 3tj3 by Molmil
Structure of importin a5 bound to the N-terminus of Nup50
Descriptor: Importin subunit alpha-1, Nuclear pore complex protein Nup50
Authors:Pumroy, R, Nardozzi, J.D, Hart, D.J, Root, M.J, Cingolani, G.
Deposit date:2011-08-23
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha 5.
J.Biol.Chem., 287, 2012
3N4Q
DownloadVisualize
BU of 3n4q by Molmil
Human cytomegalovirus terminase nuclease domain, Mn soaked
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, TERMINASE SUBUNIT UL89 PROTEIN
Authors:Nadal, M, Mas, P.J, Blanco, A.G, Arnan, C, Sola, M, Hart, D.J, Coll, M.
Deposit date:2010-05-22
Release date:2010-10-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain.
Proc.Natl.Acad.Sci.USA, 107, 2010
3N4P
DownloadVisualize
BU of 3n4p by Molmil
Human cytomegalovirus terminase nuclease domain
Descriptor: MAGNESIUM ION, Terminase subunit UL89 protein
Authors:Nadal, M, Mas, P.J, Blanco, A.G, Arnan, C, Sola, M, Hart, D.J, Coll, M.
Deposit date:2010-05-22
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain.
Proc.Natl.Acad.Sci.USA, 107, 2010
409D
DownloadVisualize
BU of 409d by Molmil
CRYSTAL STRUCTURE OF AN RNA R(CCCIUGGG) WITH THREE INDEPENDENT DUPLEXES INCORPORATING TANDEM I.U WOBBLES
Descriptor: RNA (5'-R(*CP*CP*CP*IP*UP*GP*GP*G)-3')
Authors:Pan, B, Mitra, S.N, Sun, L, Hart, D, Sundaralingam, M.
Deposit date:1998-06-26
Release date:1999-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of an RNA octamer duplex r(CCCIUGGG)2 incorporating tandem I.U wobbles.
Nucleic Acids Res., 26, 1998
2WP2
DownloadVisualize
BU of 2wp2 by Molmil
Structure of Brdt bromodomain BD1 bound to a diacetylated histone H4 peptide.
Descriptor: BROMODOMAIN TESTIS-SPECIFIC PROTEIN, HISTONE H4
Authors:Moriniere, J, Rousseaux, S, Steuerwald, U, Soler-Lopez, M, Curtet, S, Vitte, A.-L, Govin, J, Gaucher, J, Sadoul, K, Hart, D.J, Krijgsveld, J, Khochbin, S, Mueller, C.W, Petosa, C.
Deposit date:2009-08-02
Release date:2009-09-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Cooperative Binding of Two Acetylation Marks on a Histone Tail by a Single Bromodomain.
Nature, 461, 2009
2XZS
DownloadVisualize
BU of 2xzs by Molmil
Death associated protein kinase 1 residues 1-312
Descriptor: DEATH ASSOCIATED KINASE 1, MAGNESIUM ION
Authors:Yumerefendi, H, Mas, P.J, Dordevic, N, McCarthy, A.A, Hart, D.J.
Deposit date:2010-11-29
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Death-Associated Protein Kinase Activity is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites.
Structure, 24, 2016
2WP1
DownloadVisualize
BU of 2wp1 by Molmil
Structure of Brdt bromodomain 2 bound to an acetylated histone H3 peptide
Descriptor: BROMODOMAIN TESTIS-SPECIFIC PROTEIN, HISTONE H3
Authors:Moriniere, J, Rousseaux, S, Steuerwald, U, Soler-Lopez, M, Curtet, S, Vitte, A.-L, Govin, J, Gaucher, J, Sadoul, K, Hart, D.J, Krijgsveld, J, Khochbin, S, Mueller, C.W, Petosa, C.
Deposit date:2009-08-02
Release date:2009-09-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cooperative Binding of Two Acetylation Marks on a Histone Tail by a Single Bromodomain.
Nature, 461, 2009
2W69
DownloadVisualize
BU of 2w69 by Molmil
Influenza polymerase fragment
Descriptor: MANGANESE (II) ION, POLYMERASE ACIDIC PROTEIN, SULFATE ION
Authors:Dias, A, Bouvier, D, Crepin, T, McCarthy, A.A, Hart, D.J, Baudin, F, Cusack, S, Ruigrok, R.W.H.
Deposit date:2008-12-17
Release date:2009-02-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The CAP-Snatching Endonuclease of Influenza Virus Polymerase Resides in the Pa Subunit
Nature, 458, 2009
2VY8
DownloadVisualize
BU of 2vy8 by Molmil
The 627-domain from influenza A virus polymerase PB2 subunit with Glu- 627
Descriptor: POLYMERASE BASIC PROTEIN 2
Authors:Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D.
Deposit date:2008-07-19
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit
Plos Pathog., 4, 2008
2VQZ
DownloadVisualize
BU of 2vqz by Molmil
Structure of the cap-binding domain of influenza virus polymerase subunit PB2 with bound m7GTP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, POLYMERASE BASIC PROTEIN 2
Authors:Guilligay, D, Tarendeau, F, Resa-Infante, P, Coloma, R, Crepin, T, Sehr, P, Lewis, J, Ruigrok, R.W.H, Ortin, J, Hart, D.J, Cusack, S.
Deposit date:2008-03-21
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structural Basis for CAP Binding by Influenza Virus Polymerase Subunit Pb2.
Nat.Struct.Mol.Biol., 15, 2008
2VY7
DownloadVisualize
BU of 2vy7 by Molmil
The 627-domain from influenza A virus polymerase PB2 subunit
Descriptor: POLYMERASE BASIC PROTEIN 2
Authors:Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D.
Deposit date:2008-07-18
Release date:2008-09-09
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit
Plos Pathog., 4, 2008
2Y0A
DownloadVisualize
BU of 2y0a by Molmil
Structure of DAPK1 construct residues 1-304
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DEATH-ASSOCIATED PROTEIN KINASE 1
Authors:Yumerefendi, H, Mas, P.J, Dordevic, N, McCarthy, A.A, Hart, D.J.
Deposit date:2010-12-01
Release date:2011-12-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Library-Based Construct Screening of Death-Associated Protein Kinase 1 Identifies the Minimal Calmodulin Interaction Region and Autoinhibitory Conformation of the Catalytic Domain
To be Published
2JDQ
DownloadVisualize
BU of 2jdq by Molmil
C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5
Descriptor: IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2
Authors:Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S.
Deposit date:2007-01-11
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit
Nat.Struct.Mol.Biol., 14, 2007
4G9J
DownloadVisualize
BU of 4g9j by Molmil
Protein Ser/Thr phosphatase-1 in complex with cell-permeable peptide
Descriptor: MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, synthetic peptide
Authors:Sukackaite, R, Chatterjee, J, Beullens, M, Bollen, M, Koehn, M, Hart, D.J.
Deposit date:2012-07-24
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells.
Angew.Chem.Int.Ed.Engl., 51, 2012
1CW5
DownloadVisualize
BU of 1cw5 by Molmil
SOLUTION STRUCTURE OF CARNOBACTERIOCIN B2
Descriptor: TYPE IIA BACTERIOCIN CARNOBACTERIOCIN B2
Authors:Wang, Y, Henz, M.E, Gallagher, N.L.F, Chai, S, Yan, L.Z, Gibbs, A.C, Stiles, M.E, Wishart, D.S, Vederas, J.C.
Deposit date:1999-08-25
Release date:1999-09-07
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of carnobacteriocin B2 and implications for structure-activity relationships among type IIa bacteriocins from lactic acid bacteria.
Biochemistry, 38, 1999

 

12>

221716

PDB entries from 2024-06-26

PDB statisticsPDBj update infoContact PDBjnumon