2WP1

Structure of Brdt bromodomain 2 bound to an acetylated histone H3 peptide

Summary for 2WP1

Entry DOI	10.2210/pdb2wp1/pdb
Related	2WP2
Descriptor	BROMODOMAIN TESTIS-SPECIFIC PROTEIN, HISTONE H3 (3 entities in total)
Functional Keywords	transcription peptide complex, transcription regulation, acetyllysine brdt, nucleus, coiled coil, chromosomal protein, nucleosome, transcription-peptide complex, transcription/peptide
Biological source	MUS MUSCULUS (MOUSE) More
Total number of polymer chains	4
Total formula weight	31878.76
Authors	Moriniere, J.,Rousseaux, S.,Steuerwald, U.,Soler-Lopez, M.,Curtet, S.,Vitte, A.-L.,Govin, J.,Gaucher, J.,Sadoul, K.,Hart, D.J.,Krijgsveld, J.,Khochbin, S.,Mueller, C.W.,Petosa, C. (deposition date: 2009-08-02, release date: 2009-09-22, Last modification date: 2023-12-20)
Primary citation	Moriniere, J.,Rousseaux, S.,Steuerwald, U.,Soler-Lopez, M.,Curtet, S.,Vitte, A.-L.,Govin, J.,Gaucher, J.,Sadoul, K.,Hart, D.J.,Krijgsveld, J.,Khochbin, S.,Mueller, C.W.,Petosa, C. Cooperative Binding of Two Acetylation Marks on a Histone Tail by a Single Bromodomain. Nature, 461:664-, 2009 Cited by PubMed: 19794495 DOI: 10.1038/NATURE08397 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation