2WP1

Structure of Brdt bromodomain 2 bound to an acetylated histone H3 peptide

Functional Information from PROSITE/UniProt

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
P	LYS14-LEU20

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site_id	PS00633
Number of Residues	60
Details	BROMODOMAIN_1 Bromodomain signature. AwpFynpvDadalglhNYYdvVknpMdlgtIkgkmdnqe..Ykdayefaadvrl.MfmNCykY

Chain	Residue	Details
A	ALA291-TYR350

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P68431

Chain	Residue	Details
P	LYS14
Q	LYS14

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:15339660

Chain	Residue	Details
P	ARG17
Q	ARG17

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site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:17194708

Chain	Residue	Details
P	ALY18
P	LYS23
Q	ALY18
Q	LYS23

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site_id	SWS_FT_FI4
Number of Residues	2
Details	LIPID: N6-decanoyllysine => ECO:0000250|UniProtKB:P68431

Chain	Residue	Details
P	ALY18
Q	ALY18

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