2WP2

Structure of Brdt bromodomain BD1 bound to a diacetylated histone H4 peptide.

Summary for 2WP2

Entry DOI	10.2210/pdb2wp2/pdb
Related	1F66 1U35 2WP1
Descriptor	BROMODOMAIN TESTIS-SPECIFIC PROTEIN, HISTONE H4 (3 entities in total)
Functional Keywords	transcription-peptide complex, transcription regulation, brdt, acetyllysine, nucleus, coiled coil, chromosomal protein, nucleosome, transcription/peptide
Biological source	MUS MUSCULUS (MOUSE) More
Total number of polymer chains	4
Total formula weight	32709.93
Authors	Moriniere, J.,Rousseaux, S.,Steuerwald, U.,Soler-Lopez, M.,Curtet, S.,Vitte, A.-L.,Govin, J.,Gaucher, J.,Sadoul, K.,Hart, D.J.,Krijgsveld, J.,Khochbin, S.,Mueller, C.W.,Petosa, C. (deposition date: 2009-08-02, release date: 2009-09-22, Last modification date: 2019-05-08)
Primary citation	Moriniere, J.,Rousseaux, S.,Steuerwald, U.,Soler-Lopez, M.,Curtet, S.,Vitte, A.-L.,Govin, J.,Gaucher, J.,Sadoul, K.,Hart, D.J.,Krijgsveld, J.,Khochbin, S.,Mueller, C.W.,Petosa, C. Cooperative Binding of Two Acetylation Marks on a Histone Tail by a Single Bromodomain. Nature, 461:664-, 2009 Cited by PubMed: 19794495 DOI: 10.1038/NATURE08397 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.37 Å)

Structure validation