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PDB: 753 件
6QLD
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Structure of inner kinetochore CCAN-Cenp-A complex
分子名称: DNA (125-MER), Histone H2A.1, Histone H2B.1, ...
著者Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D.
登録日2019-01-31
公開日2019-10-02
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.15 Å)
主引用文献Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
6QLF
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Structure of inner kinetochore CCAN complex with mask1
分子名称: Inner kinetochore subunit AME1, Inner kinetochore subunit CHL4, Inner kinetochore subunit CTF19, ...
著者Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D.
登録日2019-01-31
公開日2019-10-02
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
5LCW
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Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Alfieri, C, Chang, L, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D.
登録日2016-06-22
公開日2016-08-10
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular basis of APC/C regulation by the spindle assembly checkpoint.
Nature, 536, 2016
8PKP
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Cryo-EM structure of the apo Anaphase-promoting complex/cyclosome (APC/C) at 3.2 Angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2023-06-27
公開日2023-07-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
To Be Published
5G04
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BU of 5g04 by Molmil
Structure of the human APC-Cdc20-Hsl1 complex
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D.
登録日2016-03-16
公開日2016-05-25
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
5A31
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Structure of the human APC-Cdh1-Hsl1-UbcH10 complex.
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Chang, L, Zhang, Z, Yang, J, Mclaughlin, S.H, Barford, D.
登録日2015-05-26
公開日2015-11-18
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Atomic Structure of the Apc/C and its Mechanism of Protein Ubiquitination.
Nature, 522, 2015
4UI9
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Atomic structure of the human Anaphase-Promoting Complex
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
登録日2015-03-27
公開日2015-06-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
7ON1
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Cenp-A nucleosome in complex with Cenp-C
分子名称: BJ4_G0006610.mRNA.1.CDS.1, BJ4_G0007000.mRNA.1.CDS.1, DNA (123-MER), ...
著者Yan, K, Yang, J, Zhang, Z, Barford, D.
登録日2021-05-25
公開日2021-07-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Cenp-A nucleosome in complex with Cenp-C
To Be Published
6YPC
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BU of 6ypc by Molmil
Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9 angstroms
分子名称: Inner kinetochore subunit CNN1, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, ...
著者Bellini, D, Zhang, Z, Barford, D.
登録日2020-04-15
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the Cenp-HIKHead-TW sub-module of the inner kinetochore CCAN complex.
Nucleic Acids Res., 48, 2020
7C8U
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BU of 7c8u by Molmil
The crystal structure of COVID-19 main protease in complex with GC376
分子名称: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase
著者Luan, X, Shang, W, Wang, Y, Yin, W, Jiang, Y, Feng, S, Wang, Y, Liu, M, Zhou, R, Zhang, Z, Wang, F, Cheng, W, Gao, M, Wang, H, Wu, W, Tian, R, Tian, Z, Jin, Y, Jiang, H.W, Zhang, L, Xu, H.E, Zhang, S.
登録日2020-06-03
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The crystal structure of COVID-19 main protease in complex with GC376
To Be Published
4XBS
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BU of 4xbs by Molmil
2-deoxyribose-5-phosphate aldolase mutant - E78K
分子名称: Deoxyribose-phosphate aldolase
著者Jiao, X.-C, Pan, J, Xu, G.-C, Kong, X.-D, Chen, Q, Zhang, Z.-J, Xu, J.-H.
登録日2014-12-17
公開日2015-11-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Efficient synthesis of a statin precursor in high space-time yield by a new aldehyde-tolerant aldolase identified from Lactobacillus brevis
Catalysis Science And Technology, 5, 2015
4XPU
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BU of 4xpu by Molmil
The crystal structure of EndoV from E.coli
分子名称: Endonuclease V
著者Xie, W, Zhang, Z.
登録日2015-01-18
公開日2015-08-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of E. coli endonuclease V, an essential enzyme for deamination repair
Sci Rep, 5, 2015
4XBK
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BU of 4xbk by Molmil
2-deoxyribose-5-phosphate aldolase from Lactobacillus brevis
分子名称: ACETIC ACID, Deoxyribose-phosphate aldolase
著者Jiao, X.-C, Pan, J, Xu, G.-C, Kong, X.-D, Chen, Q, Zhang, Z.-J, Xu, J.-H.
登録日2014-12-17
公開日2015-11-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.951 Å)
主引用文献Efficient synthesis of a statin precursor in high space-time yield by a new aldehyde-tolerant aldolase identified from Lactobacillus brevis
Catalysis Science And Technology, 5, 2015
8GS4
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BU of 8gs4 by Molmil
Cryo-EM structure of human Neuroligin 2
分子名称: Neuroligin-2
著者Zhang, H, Zhang, Z, Hou, M.
登録日2022-09-04
公開日2023-03-01
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders.
Front Endocrinol, 13, 2022
5KQL
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BU of 5kql by Molmil
Co-crystal structure of LMW-PTP in complex with 2-oxo-1-phenyl-2-(phenylamino)ethanesulfonic acid
分子名称: (1~{S})-2-oxidanylidene-1-phenyl-2-phenylazanyl-ethanesulfonic acid, Low molecular weight phosphotyrosine protein phosphatase
著者Wang, J, Zhang, Z.-Y, Yu, Z.-H.
登録日2016-07-06
公開日2016-10-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
5KQP
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Crystal structure of Apo-form LMW-PTP
分子名称: Low molecular weight phosphotyrosine protein phosphatase
著者Wang, J, Zhang, Z.-Y, Yu, Z.-H.
登録日2016-07-06
公開日2016-10-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.052 Å)
主引用文献Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
5KQG
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BU of 5kqg by Molmil
Co-crystal structure of LMW-PTP in complex with 2-(benzothiazol-2-ylamino)-2-oxo-1-phenylethanesulfonic acid
分子名称: (1~{S})-2-(1,3-benzothiazol-2-ylamino)-2-oxidanylidene-1-phenyl-ethanesulfonic acid, Low molecular weight phosphotyrosine protein phosphatase
著者Wang, J, Zhang, Z.-Y, Yu, Z.-H.
登録日2016-07-06
公開日2016-10-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
5KQM
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Co-crystal structure of LMW-PTP in complex with MES
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Low molecular weight phosphotyrosine protein phosphatase
著者Wang, J, Zhang, Z.-Y, Yu, Z.-H.
登録日2016-07-06
公開日2016-10-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
7AAP
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BU of 7aap by Molmil
Nsp7-Nsp8-Nsp12 SARS-CoV2 RNA-dependent RNA polymerase in complex with template:primer dsRNA and favipiravir-RTP
分子名称: MAGNESIUM ION, Non-structural protein 12, Non-structural protein 7, ...
著者Naydenova, K, Muir, K.W, Wu, L.F, Zhang, Z, Coscia, F, Peet, M, Castro-Hartman, P, Qian, P, Sader, K, Dent, K, Kimanius, D, Sutherland, J.D, Lowe, J, Barford, D, Russo, C.J.
登録日2020-09-04
公開日2020-09-23
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP.
Proc.Natl.Acad.Sci.USA, 118, 2021
8JG8
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BU of 8jg8 by Molmil
The crystal structure of human aurka kinase domain in the complex with aurka-compound 25
分子名称: 4-[5-[3-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine, Aurora kinase A
著者Zhu, C.J, Zhang, Z.M.
登録日2023-05-19
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2.90002346 Å)
主引用文献Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development.
Angew.Chem.Int.Ed.Engl., 63, 2024
5BK8
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Cancer-associated SHP2/T507K mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Zhang, Z.Y.
登録日2019-06-01
公開日2020-04-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Mechanistic insights explain the transforming potential of the T507K substitution in the protein-tyrosine phosphatase SHP2.
J.Biol.Chem., 295, 2020
7YE6
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BAM-EspP complex structure with BamA-N427C/EspP-R1297C mutations in nanodisc
分子名称: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
著者Shen, C, Chang, S, Luo, Q, Zhang, Z, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhang, X, Tang, X, Dong, H.
登録日2022-07-05
公開日2023-07-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of BAM-mediated outer membrane beta-barrel protein assembly.
Nature, 617, 2023
7YE4
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BAM-EspP complex structure with BamA-G431C and G781C/EspP-N1293C and A1043C mutations in nanodisc
分子名称: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
著者Shen, C, Chang, S, Luo, Q, Zhang, Z, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhang, X, Tang, X, Dong, H.
登録日2022-07-05
公開日2023-07-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of BAM-mediated outer membrane beta-barrel protein assembly.
Nature, 617, 2023
6IWK
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The Structure of Maltooligosaccharide-forming Amylase from Pseudomonas saccharophila STB07
分子名称: CALCIUM ION, GLYCEROL, Glucan 1,4-alpha-maltotetraohydrolase
著者Li, Z.F, Ban, X.F, Zhang, Z.Q, Li, C.M, Gu, Z.B, Jin, T.C, Li, Y.L, Shang, Y.H.
登録日2018-12-05
公開日2019-12-11
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Structure of maltotetraose-forming amylase from Pseudomonas saccharophila STB07 provides insights into its product specificity.
Int.J.Biol.Macromol., 154, 2020
7FIR
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The crystal structure of beta-1,2-mannobiose phosphorylase in complex with 1,4-mannobiose
分子名称: Beta-1,2-mannobiose phosphorylase, PENTAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ...
著者Dai, L, Chang, Z, Yang, J, Liu, W, Yang, Y, Chen, C.-C, Zhang, L, Huang, J, Sun, Y, Guo, R.-T.
登録日2021-08-01
公開日2022-01-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural investigation of a thermostable 1,2-beta-mannobiose phosphorylase from Thermoanaerobacter sp. X-514.
Biochem.Biophys.Res.Commun., 579, 2021

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