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PDB: 861 件

2YIN
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STRUCTURE OF THE COMPLEX BETWEEN Dock2 AND Rac1.
分子名称: DEDICATOR OF CYTOKINESIS PROTEIN 2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1
著者Kulkarni, K.A, Yang, J, Zhang, Z, Barford, D.
登録日2011-05-16
公開日2011-05-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (Dock) Nucleotide Exchange Factors.
J.Biol.Chem., 286, 2011
3J2N
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The X-ray structure of the gp15 hexamer and the model of the gp18 protein fitted into the cryo-EM reconstruction of the contracted T4 tail
分子名称: Tail connector protein Gp15, Tail sheath protein Gp18
著者Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G.
登録日2012-11-10
公開日2013-03-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (16 Å)
主引用文献The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
3J2M
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The X-ray structure of the gp15 hexamer and the model of the gp18 protein fitted into the cryo-EM reconstruction of the extended T4 tail
分子名称: Tail connector protein Gp15, Tail sheath protein Gp18
著者Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G.
登録日2012-11-09
公開日2013-03-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (15 Å)
主引用文献The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
1CFM
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CYTOCHROME F FROM CHLAMYDOMONAS REINHARDTII
分子名称: CYTOCHROME F, PROTOPORPHYRIN IX CONTAINING FE
著者Chi, Y.I, Huang, L.S, Zhang, Z, Fernandez-Velasco, J.G, Malkin, R, Berry, E.A.
登録日1998-09-18
公開日1999-04-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure of a truncated form of cytochrome f from chlamydomonas reinhardtii.
Biochemistry, 39, 2000
7CJL
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Metallo-Beta-Lactamase VIM-2 in complex with (S)-N-(3-(2H-tetrazol-5-yl)phenyl)-3-mercapto-2-methylpropanamide
分子名称: (S)-N-(3-(2H-tetrazol-5-yl)phenyl)-3-mercapto-2-methylpropanamide, Beta-lactamase class B VIM-2, FORMIC ACID, ...
著者Yan, Y.-H, Chen, J, Zhan, Z, Yu, Z.-J, Li, G, Li, G.-B, Guo, L, Wu, Y.
登録日2020-07-11
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.789 Å)
主引用文献Discovery of mercaptopropanamide-substituted aryl tetrazoles as new broad-spectrum metallo-beta-lactamase inhibitors.
Rsc Adv, 10, 2020
1YPT
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CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE
分子名称: PROTEIN-TYROSINE PHOSPHATASE YERSINIA (CATALYTIC DOMAIN)
著者Stuckey, J.A, Schubert, H.L, Fauman, E.B, Zhang, Z.-Y, Dixon, J.E, Saper, M.A.
登録日1994-09-16
公開日1994-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate.
Nature, 370, 1994
7E8C
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SARS-CoV-2 S-6P in complex with 9 Fabs
分子名称: 368-2 H, 368-2 L, 604 H, ...
著者Du, S, Xiao, J, Zhang, Z.
登録日2021-03-01
公開日2021-06-09
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E7O
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Cryo-EM structure of human ABCA4 in NRPE-bound state
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ...
著者Xie, T, Zhang, Z.K, Gong, X.
登録日2021-02-26
公開日2021-06-30
最終更新日2021-07-07
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of substrate recognition and translocation by human ABCA4.
Nat Commun, 12, 2021
7K0O
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 3
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0K
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, 3KS-bound
分子名称: 3-Dehydrosphinganine, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0J
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa protomer
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0Q
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound
分子名称: Myriocin, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0L
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, myriocin-bound
分子名称: Myriocin, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0P
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 4
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0M
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0I
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
5B1Q
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Human herpesvirus 6B tegument protein U14
分子名称: GLYCEROL, U14 protein
著者Wang, B, Nishimura, M, Tang, H, Kawabata, A, Mahmoud, N.F, Khanlari, Z, Hamada, D, Tsuruta, H, Mori, Y.
登録日2015-12-11
公開日2016-04-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of Human Herpesvirus 6B Tegument Protein U14.
Plos Pathog., 12, 2016
4E57
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Crystal Structure of spacer 6aa-shortened cephalosporin acylase mutant
分子名称: CADMIUM ION, Cephalosporin acylase
著者Yin, J, Zhang, Z, Wu, G, Huang, X.
登録日2012-03-14
公開日2013-03-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献spacer shortened Cephalosporin acylase
To be Published
1X11
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X11 PTB DOMAIN
分子名称: 13-MER PEPTIDE, X11
著者Lee, C.-H, Zhang, Z, Kuriyan, J.
登録日1997-07-28
公開日1998-01-14
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997
3EB1
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Crystal structure PTP1B complex with small molecule inhibitor LZP-25
分子名称: 4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acid, Tyrosine-protein phosphatase non-receptor type 1
著者Liu, S, Zheng, L.-F, Wu, L, Yu, X, Xue, T, Gunawan, A.M, Long, Y.-Q, Zhang, Z.-Y.
登録日2008-08-26
公開日2009-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors.
J.Am.Chem.Soc., 130, 2008
3KAE
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Cdc27 N-terminus
分子名称: CHLORIDE ION, GLYCEROL, Possible protein of nuclear scaffold, ...
著者Barford, D, Zhang, Z, Roe, S.M.
登録日2009-10-19
公開日2010-03-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture
J.Mol.Biol., 397, 2010
3J2O
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Model of the bacteriophage T4 fibritin based on the cryo-EM reconstruction of the contracted T4 tail containing the phage collar and whiskers
分子名称: Fibritin
著者Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A.A, Arisaka, F, Rao, V.B, Rossmann, M.G.
登録日2012-11-12
公開日2013-03-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (25 Å)
主引用文献The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
5ZBA
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Crystal structure of Rtt109-Asf1-H3-H4-CoA complex
分子名称: COENZYME A, DNA damage response protein Rtt109, putative, ...
著者Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M.
登録日2018-02-10
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
3FXV
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Identification of an N-oxide pyridine GW4064 analogue as a potent FXR agonist
分子名称: 12-meric peptide from Nuclear receptor coactivator 1, 6-(4-{[3-(3,5-dichloropyridin-4-yl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-2-methylphenyl)-1-methyl-1H-indole-3-carbox ylic acid, NR1H4 protein
著者Feng, S, Yang, M, He, Y, Chen, L, Zhang, Z, Wang, Z, Hong, D, Richter, H, Benson, G.M, Bleicher, K, Grether, U, Martin, R, Plancher, J.-M, Kuhn, B, Rudolph, M.G.
登録日2009-01-21
公開日2009-04-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist
Bioorg.Med.Chem.Lett., 19, 2009
4H5S
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Complex structure of Necl-2 and CRTAM
分子名称: Cell adhesion molecule 1, Cytotoxic and regulatory T-cell molecule
著者Zhang, S, Lu, G, Qi, J, Li, Y, Zhang, Z, Zhang, B, Yan, J, Gao, G.F.
登録日2012-09-18
公開日2013-08-07
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Competition of cell adhesion and immune recognition: insights into the interaction between CRTAM and nectin-like 2.
Structure, 21, 2013

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