7K0J

Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa protomer

Summary for 7K0J
EMDB information22599
DescriptorSerine palmitoyltransferase 1, Serine palmitoyltransferase 2, Serine palmitoyltransferase small subunit A, ... (5 entities in total)
Functional Keywordssphingolipid, membrane protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight126049.32
Authors
Wang, Y.,Niu, Y.,Zhang, Z.,Zhao, H.,Myasnikov, A.,Kalathur, R.,Lee, C.H. (deposition date: 2020-09-04, release date: 2021-02-24, Last modification date: 2021-03-24)
Primary citationDunn, T.M.,Gable, K.,Gupta, S.D.,Han, G.,Kalathur, R.C.,Lee, C.H.,Myasnikov, A.G.,Niu, Y.,Somashekarappa, N.,Wang, Y.,Zhang, Z.,Zhao, H.
Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28:240-248, 2021
PubMed: 33558761
DOI: 110.1038/s41594-020-00551-9
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.1 Å)
Structure validation
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PDB entries from 2021-06-16