7CJL

Metallo-Beta-Lactamase VIM-2 in complex with (S)-N-(3-(2H-tetrazol-5-yl)phenyl)-3-mercapto-2-methylpropanamide

Summary for 7CJL

• Entry DOI: 10.2210/pdb7cjl/pdb
• Descriptor: Beta-lactamase class B VIM-2, ZINC ION, FORMIC ACID, ... (5 entities in total)
• Functional Keywords: metallo-beta-lactamase vim-2, vim-2, hydrolase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 50193.18

Authors

Yan, Y.-H.,Chen, J.,Zhan, Z.,Yu, Z.-J.,Li, G.,Li, G.-B.,Guo, L.,Wu, Y. (deposition date: 2020-07-11, release date: 2021-07-14, Last modification date: 2023-11-29)

• Primary citation: Yan, Y.H.,Chen, J.,Zhan, Z.,Yu, Z.J.,Li, G.,Guo, L.,Li, G.B.,Wu, Y.,Zheng, Y.; Discovery of mercaptopropanamide-substituted aryl tetrazoles as new broad-spectrum metallo-beta-lactamase inhibitors.; Rsc Adv, 10:31377-31384, 2020; PubMed: 35520685; DOI: 10.1039/d0ra06405j

Experimental method

X-RAY DIFFRACTION (1.789 Å)