7CJL
Metallo-Beta-Lactamase VIM-2 in complex with (S)-N-(3-(2H-tetrazol-5-yl)phenyl)-3-mercapto-2-methylpropanamide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0008800 | molecular_function | beta-lactamase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017001 | biological_process | antibiotic catabolic process |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 301 |
| Chain | Residue |
| B | HIS114 |
| B | HIS116 |
| B | HIS179 |
| B | ZN302 |
| B | G0O304 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue ZN B 302 |
| Chain | Residue |
| B | ZN301 |
| B | G0O304 |
| B | HOH481 |
| B | ASP118 |
| B | ARG119 |
| B | CYS198 |
| B | HIS240 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue FMT B 303 |
| Chain | Residue |
| B | VAL107 |
| B | HOH450 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue G0O B 304 |
| Chain | Residue |
| B | PHE62 |
| B | TYR67 |
| B | TRP87 |
| B | HIS116 |
| B | ASP118 |
| B | HIS179 |
| B | GLY209 |
| B | ASN210 |
| B | HIS240 |
| B | ZN301 |
| B | ZN302 |
| B | HOH481 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | HIS114 |
| A | HIS116 |
| A | HIS179 |
| A | ZN302 |
| A | G0O303 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 302 |
| Chain | Residue |
| A | ASP118 |
| A | CYS198 |
| A | HIS240 |
| A | ZN301 |
| A | G0O303 |
| A | HOH485 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue G0O A 303 |
| Chain | Residue |
| A | PHE62 |
| A | TYR67 |
| A | TRP87 |
| A | HIS116 |
| A | ASP118 |
| A | HIS179 |
| A | ASN210 |
| A | ZN301 |
| A | ZN302 |
| A | HOH485 |
