7W1L
| Crystal structure of carboxylesterase mutant from Thermobifida fusca with C8X | 分子名称: | Carboxylesterase, bis(2-hydroxyethyl) benzene-1,4-dicarboxylate | 著者 | Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W. | 登録日 | 2021-11-19 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization Acs Catalysis, 12, 2022
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7YKO
| Crystal structure of a novel alpha/beta hydrolase mutant from thermomonospora curvata in complex with pentane-1,5-diol | 分子名称: | Triacylglycerol lipase, pentane-1,5-diol | 著者 | Han, X, Jian, G, Bornscheuer, U.T, Wei, R, Liu, W. | 登録日 | 2022-07-23 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Crystal structure of a novel alpha/beta hydrolase mutant from thermomonospora curvata in complex with pentane-1,5-diol To Be Published
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7YKP
| Crystal structure of a novel alpha/beta hydrolase from thermomonospora curvata with glycerol | 分子名称: | GLYCEROL, Triacylglycerol lipase | 著者 | Han, X, Jian, G, Bornscheuer, U.T, Wei, R, Liu, W. | 登録日 | 2022-07-23 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Crystal structure of a novel alpha/beta hydrolase from thermomonospora curvata with glycerol To Be Published
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7YKQ
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8HK1
| The cryo-EM structure of human pre-17S U2 snRNP | 分子名称: | ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... | 著者 | Zhang, X, Zhan, X, Shi, Y. | 登録日 | 2022-11-24 | 公開日 | 2023-03-08 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly. Nat Commun, 14, 2023
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8HMY
| Cryo-EM structure of the human pre-catalytic TSEN/pre-tRNA complex | 分子名称: | Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ... | 著者 | Zhang, X, Yang, F, Zhan, X, Shi, Y. | 登録日 | 2022-12-06 | 公開日 | 2023-04-19 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease. Mol.Cell, 83, 2023
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8HMZ
| Cryo-EM structure of the human post-catalytic TSEN/pre-tRNA complex | 分子名称: | Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ... | 著者 | Zhang, X, Yang, F, Zhan, X, Shi, Y. | 登録日 | 2022-12-06 | 公開日 | 2023-04-19 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease. Mol.Cell, 83, 2023
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1F3L
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1PEG
| Structural basis for the product specificity of histone lysine methyltransferases | 分子名称: | Histone H3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | 著者 | Zhang, X, Yang, Z, Khan, S.I, Horton, J.R, Tamaru, H, Selker, E.U, Cheng, X. | 登録日 | 2003-05-21 | 公開日 | 2003-08-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Structural basis for the product specificity of histone lysine methyltransferases Mol.Cell, 12, 2003
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3JB7
| In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | 分子名称: | CPV RNA-dependent RNA polymerase, CYTIDINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | 登録日 | 2015-08-03 | 公開日 | 2015-10-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus. Nature, 527, 2015
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3JB6
| In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, VP1 CSP, ... | 著者 | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | 登録日 | 2015-08-02 | 公開日 | 2015-10-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus. Nature, 527, 2015
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1HQK
| CRYSTAL STRUCTURE ANALYSIS OF LUMAZINE SYNTHASE FROM AQUIFEX AEOLICUS | 分子名称: | 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE | 著者 | Zhang, X, Meining, W, Fischer, M, Bacher, A, Ladenstein, R. | 登録日 | 2000-12-18 | 公開日 | 2001-12-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | X-ray structure analysis and crystallographic refinement of lumazine synthase from the hyperthermophile Aquifex aeolicus at 1.6 A resolution: determinants of thermostability revealed from structural comparisons. J.Mol.Biol., 306, 2001
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1H0C
| The crystal structure of human alanine:glyoxylate aminotransferase | 分子名称: | (AMINOOXY)ACETIC ACID, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Zhang, X, Danpure, C.J, Roe, S.M, Pearl, L.H. | 登録日 | 2002-06-17 | 公開日 | 2003-06-12 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of Alanine:Glyoxylate Aminotransferase and the Relationship between Genotype and Enzymatic Phenotype in Primary Hyperoxaluria Type 1. J.Mol.Biol., 331, 2003
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6AHD
| The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | 著者 | Zhan, X, Yan, C, Zhang, X, Shi, Y. | 登録日 | 2018-08-17 | 公開日 | 2018-11-14 | 最終更新日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
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8G05
| Cryo-EM structure of an orphan GPCR-Gi protein signaling complex | 分子名称: | 6-(octylamino)pyrimidine-2,4(3H,5H)-dione, CHOLESTEROL, G-protein coupled receptor 84, ... | 著者 | Zhang, X, Wang, Y.J, Li, X, Liu, G.B, Gong, W.M, Zhang, C. | 登録日 | 2023-01-31 | 公開日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Pro-phagocytic function and structural basis of GPR84 signaling. Nat Commun, 14, 2023
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8H10
| Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-2 Conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | 登録日 | 2022-09-30 | 公開日 | 2022-10-19 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023
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8H14
| Structure of SARS-CoV-1 Spike Protein with Engineered x3 Disulfide (D414C and V969C), Locked-1 Conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, Spike glycoprotein | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | 登録日 | 2022-09-30 | 公開日 | 2022-10-19 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023
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8H13
| Structure of SARS-CoV-1 Spike Protein with Engineered x2 Disulfide (G400C and V969C), Closed Conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | 登録日 | 2022-09-30 | 公開日 | 2022-10-19 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023
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8H16
| Structure of SARS-CoV-1 Spike Protein (S/native) at pH 5.5, Open Conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | 登録日 | 2022-09-30 | 公開日 | 2022-11-09 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.35534 Å) | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023
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8H11
| Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Closed Conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | 登録日 | 2022-09-30 | 公開日 | 2022-11-09 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023
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8H0Z
| Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-122 Conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | 登録日 | 2022-09-30 | 公開日 | 2022-11-09 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023
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8H0Y
| Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-112 Conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, LINOLEIC ACID, ... | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | 登録日 | 2022-09-30 | 公開日 | 2022-11-09 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023
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8H12
| Structure of SARS-CoV-1 Spike Protein with Engineered x2 Disulfide (G400C and V969C), Locked-2 Conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | 登録日 | 2022-09-30 | 公開日 | 2022-11-09 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.44681 Å) | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023
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8H0X
| Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-1 Conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, LINOLEIC ACID, ... | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | 登録日 | 2022-09-30 | 公開日 | 2022-11-09 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023
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6LRM
| Crystal structure of PDE4D catalytic domain in complex with arctigenin | 分子名称: | 1,2-ETHANEDIOL, Arctigenin, MAGNESIUM ION, ... | 著者 | Zhang, X.L, Li, M.J, Xu, Y.C. | 登録日 | 2020-01-16 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation. J Adv Res, 33, 2021
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