7ARK
 
 | | LolCDE in complex with AMP-PNP in the closed NBD state | | 分子名称: | Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE, ... | | 著者 | Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2020-10-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
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7ARJ
 | | LolCDE in complex with lipoprotein and AMPPNP complex undimerized form | | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ... | | 著者 | Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2020-10-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
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7ARI
 | | LolCDE apo structure | | 分子名称: | Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE | | 著者 | Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2020-10-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
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7ARH
 | | LolCDE in complex with lipoprotein | | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ... | | 著者 | Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2020-10-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
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1FLC
 | | X-RAY STRUCTURE OF THE HAEMAGGLUTININ-ESTERASE-FUSION GLYCOPROTEIN OF INFLUENZA C VIRUS | | 分子名称: | HAEMAGGLUTININ-ESTERASE-FUSION GLYCOPROTEIN, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Rosenthal, P.B, Zhang, X, Formanowski, F, Fitz, W, Wong, C.H, Meier-Ewert, H, Skehel, J.J, Wiley, D.C. | | 登録日 | 1999-02-22 | | 公開日 | 2000-03-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus.
Nature, 396, 1998
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7XL5
 | | Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase | | 分子名称: | NADP-dependent isopropanol dehydrogenase | | 著者 | Jiang, Y.Y, Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D. | | 登録日 | 2022-04-21 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | Engineering the hydrogen transfer pathway of an alcohol dehydrogenase to increase activity by rational enzyme design
Mol Catal, 530, 2022
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1G55
 | | Structure of human DNMT2, an enigmatic DNA methyltransferase homologue | | 分子名称: | BETA-MERCAPTOETHANOL, DNA CYTOSINE METHYLTRANSFERASE DNMT2, GLYCEROL, ... | | 著者 | Dong, A, Yoder, J.A, Zhang, X, Zhou, L, Bestor, T.H, Cheng, X. | | 登録日 | 2000-10-30 | | 公開日 | 2001-01-17 | | 最終更新日 | 2018-06-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA.
Nucleic Acids Res., 29, 2001
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5V6B
 | | Crystal structure of GIPC1 | | 分子名称: | PDZ domain-containing protein GIPC1 | | 著者 | Shang, G, Zhang, X. | | 登録日 | 2017-03-16 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.
Elife, 6, 2017
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5V6H
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7VX2
 | | Crystal Structure of the Y53F/N55A/I80F/L114V/I116V mutant of LEH | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D. | | 登録日 | 2021-11-12 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.485 Å) | | 主引用文献 | Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.
Nat Commun, 13, 2022
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7VWM
 | | Crystal Structure of the Y53F/N55A/I116V mutant of LEH | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D. | | 登録日 | 2021-11-11 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.
Nat Commun, 13, 2022
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7VWD
 | | Crystal Structure of the Y53F/N55A mutant of LEH | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D. | | 登録日 | 2021-11-10 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.153 Å) | | 主引用文献 | Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.
Nat Commun, 13, 2022
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5V6E
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5V6T
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5V6R
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5IJB
 | | The ligand-free structure of the mouse TLR4/MD-2 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ... | | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | | 登録日 | 2016-03-01 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5IJD
 | | The crystal structure of mouse TLR4/MD-2/lipid A complex | | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | | 登録日 | 2016-03-01 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1F4H
 | | E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) | | 分子名称: | BETA-GALACTOSIDASE, MAGNESIUM ION | | 著者 | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | | 登録日 | 2000-06-07 | | 公開日 | 2001-02-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.
Protein Sci., 9, 2000
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1F4A
 | | E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) | | 分子名称: | BETA-GALACTOSIDASE, MAGNESIUM ION | | 著者 | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | | 登録日 | 2000-06-07 | | 公開日 | 2001-02-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.
Protein Sci., 9, 2000
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1F6W
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3O5X
 | | Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor | | 分子名称: | 3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3-triazol-4-yl}-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Zhang, Z.-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C, Wu, L, Gunawan, A.M, Wang, L, Chan, R.J. | | 登録日 | 2010-07-28 | | 公開日 | 2010-08-11 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
J.Med.Chem., 53, 2010
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1F9V
 | | CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION | | 著者 | Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. | | 登録日 | 2000-07-11 | | 公開日 | 2001-06-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | A structural pathway for activation of the kinesin motor ATPase.
EMBO J., 20, 2001
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1FKN
 | | Structure of Beta-Secretase Complexed with Inhibitor | | 分子名称: | MEMAPSIN 2, inhibitor | | 著者 | Hong, L, Koelsch, G, Lin, X, Wu, S, Terzyan, S, Ghosh, A, Zhang, X.C, Tang, J. | | 登録日 | 2000-08-09 | | 公開日 | 2000-10-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor.
Science, 290, 2000
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1F9U
 | | CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION | | 著者 | Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. | | 登録日 | 2000-07-11 | | 公開日 | 2001-06-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A structural pathway for activation of the kinesin motor ATPase.
EMBO J., 20, 2001
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1F9W
 | | CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION | | 著者 | Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. | | 登録日 | 2000-07-11 | | 公開日 | 2001-06-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A structural pathway for activation of the kinesin motor ATPase.
EMBO J., 20, 2001
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