8W50
 
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8KE7
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5KP0
 | | Recognition and targeting mechanisms by chaperones in flagella assembly and operation | | 分子名称: | Flagellar protein FliT,Flagellum-specific ATP synthase | | 著者 | Khanra, N.K, Rossi, P, Economou, A, Kalodimos, C.G. | | 登録日 | 2016-07-01 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Recognition and targeting mechanisms by chaperones in flagellum assembly and operation.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1JJP
 | | A(GGGG) Pentad-Containing Dimeric DNA Quadruplex Involving Stacked G(anti)G(anti)G(anti)G(syn) Tetrads | | 分子名称: | 5'-D(*GP*GP*GP*AP*GP*GP*TP*TP*TP*GP*GP*GP*AP*T)-3' | | 著者 | Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J. | | 登録日 | 2001-07-09 | | 公開日 | 2001-09-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads.
J.Mol.Biol., 311, 2001
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9C5S
 | | Disulfide-linked, antiparallel p53-derived peptide dimer (CV1) | | 分子名称: | Cellular tumor antigen p53, SULFATE ION | | 著者 | Vithanage, N, Kreitler, D.K, DiGiorno, M.C, Victorio, C.G, Sawyer, N, Outlaw, V.K. | | 登録日 | 2024-06-06 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.01 Å) | | 主引用文献 | Structural Characterization of Disulfide-Linked, p53-Derived Peptide Dimers
To Be Published
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4V11
 | | Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84 | | 分子名称: | CALCIUM ION, GLYCEROL, SYNAPTIC VESICLE GLYCOPROTEIN 2A, ... | | 著者 | Zhang, N, Gordon, S.L, Fritsch, M.J, Esoof, N, Campbell, D, Gourlay, R, Velupillai, S, Macartney, T, Peggie, M, vanAalten, D.M.F, Cousin, M.A, Alessi, D.R. | | 登録日 | 2014-09-22 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1.
J.Neurosci., 35, 2015
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7Q16
 | | Human 14-3-3 zeta fused to the BAD peptide including phosphoserine-74 | | 分子名称: | 14-3-3 protein zeta/delta,Bcl2-associated agonist of cell death | | 著者 | Sluchanko, N.N, Tugaeva, K.V, Gushchin, I, Remeeva, A, Kovalev, K, Cooley, R.B. | | 登録日 | 2021-10-18 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.356 Å) | | 主引用文献 | Crystal structure of human 14-3-3 zeta complexed with the noncanonical phosphopeptide from proapoptotic BAD.
Biochem.Biophys.Res.Commun., 583, 2021
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6UF2
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5GNE
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6NDU
 | | Structure of human PACRG-MEIG1 complex | | 分子名称: | CHLORIDE ION, Meiosis expressed gene 1 protein homolog, PHOSPHATE ION, ... | | 著者 | Khan, N, Croteau, N, Pelletier, D, Veyron, S, Trempe, J.F. | | 登録日 | 2018-12-14 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of human PACRG in complex with MEIG1
Biorxiv, 2019
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6NEP
 | | Structure of human PACRG-MEIG1 complex | | 分子名称: | CHLORIDE ION, Meiosis expressed gene 1 protein homolog, PHOSPHATE ION, ... | | 著者 | Khan, N, Croteau, N, Pelletier, D, Veyron, S, Trempe, J.F. | | 登録日 | 2018-12-18 | | 公開日 | 2019-10-23 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (2.097625 Å) | | 主引用文献 | Crystal structure of human PACRG in complex with MEIG1
Biorxiv, 2019
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7QIK
 | | SARS-CoV-2 Nucleocapsid phosphopeptide 193-200 bound to human 14-3-3 sigma | | 分子名称: | 14-3-3 protein sigma, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, ... | | 著者 | Sluchanko, N.N, Tugaeva, K.V, Smith, J.L.R, Antson, A.A. | | 登録日 | 2021-12-15 | | 公開日 | 2021-12-29 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | SARS-CoV-2 Nucleocapsid phosphopeptide 193-200 bound to human 14-3-3 sigma
To Be Published
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7QIP
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5ESW
 | | Crystal structure of Apo hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila | | 分子名称: | PHOSPHATE ION, Purine/pyrimidine phosphoribosyltransferase | | 著者 | Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H. | | 登録日 | 2015-11-17 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis
J.Struct.Biol., 194, 2016
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5ESX
 | | Crystal structure of hypoxanthine-guanine phosphoribosyltransferase complexed with GMP from Legionella pneumophila | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, Purine/pyrimidine phosphoribosyltransferase | | 著者 | Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H. | | 登録日 | 2015-11-17 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis
J.Struct.Biol., 194, 2016
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3WCL
 | | The complex structure of HsSQS wtih ligand,BPH1344 | | 分子名称: | Squalene synthase, hydrogen [(1R)-2-(3-pentadecyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate | | 著者 | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | | 登録日 | 2013-05-28 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
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3WCI
 | | The complex structure of HsSQS wtih ligand,BPH1325 | | 分子名称: | Squalene synthase, hydrogen [(1R)-1-hydroxy-2-(3-pentadecyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate | | 著者 | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | | 登録日 | 2013-05-27 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
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3WCA
 | | The complex structure of TcSQS with ligand, FSPP | | 分子名称: | Farnesyltransferase, putative, MAGNESIUM ION, ... | | 著者 | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Oldfield, E, Guo, R.T. | | 登録日 | 2013-05-26 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
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3WCH
 | | The complex structure of HsSQS wtih ligand BPH1237 | | 分子名称: | Squalene synthase, hydrogen [(1R)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-hydroxy-1-phosphonoethyl]phosphonate | | 著者 | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | | 登録日 | 2013-05-27 | | 公開日 | 2014-06-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
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3WCD
 | | The complex structure of HsSQS wtih ligand, WC-9 | | 分子名称: | 2-(4-phenoxyphenoxy)ethyl thiocyanate, Squalene synthase | | 著者 | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | | 登録日 | 2013-05-27 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
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3WCM
 | | The complex structure of HsSQS wtih ligand, ER119884 | | 分子名称: | (3R)-3-{[2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl]ethynyl}-1-azabicyclo[2.2.2]octan-3-ol, Squalene synthase | | 著者 | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | | 登録日 | 2013-05-28 | | 公開日 | 2014-06-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
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3WC9
 | | The complex structure of HsSQS wtih ligand, FSPP | | 分子名称: | S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Squalene synthase | | 著者 | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | | 登録日 | 2013-05-26 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
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3WCF
 | | The complex structure of HsSQS wtih ligand,BPH1218 | | 分子名称: | Squalene synthase, hydrogen [(1S)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate | | 著者 | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | | 登録日 | 2013-05-27 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
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3WCJ
 | | The complex structure of HsSQS wtih ligand,E5700 | | 分子名称: | (3R)-3-({2-benzyl-6-[(3R,4S)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridin-3-yl}ethynyl)-1-azabicyclo[2.2.2]octan-3-ol, Squalene synthase | | 著者 | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | | 登録日 | 2013-05-27 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
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5KS6
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