3FWZ
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![BU of 3fwz by Molmil](/molmil-images/mine/3fwz) | Crystal structure of TrkA-N domain of inner membrane protein ybaL from Escherichia coli | Descriptor: | ADENOSINE MONOPHOSPHATE, Inner membrane protein ybaL, MAGNESIUM ION | Authors: | Chang, C, Bigelow, L, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-01-19 | Release date: | 2009-02-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal structure of TrkA-N domain of inner membrane protein ybaL from Escherichia coli To be Published
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3JU3
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![BU of 3ju3 by Molmil](/molmil-images/mine/3ju3) | Crystal structure of alpha chain of probable 2-oxoacid ferredoxin oxidoreductase from Thermoplasma acidophilum | Descriptor: | 1,2-ETHANEDIOL, Probable 2-oxoacid ferredoxin oxidoreductase, alpha chain | Authors: | Chang, C, Marshall, N, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-09-14 | Release date: | 2009-09-22 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of alpha chain of probable 2-oxoacid ferredoxin oxidoreductase from Thermoplasma acidophilum To be Published
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6CX6
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7WL4
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![BU of 7wl4 by Molmil](/molmil-images/mine/7wl4) | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor SLP-50 | Descriptor: | Bromodomain-containing protein 4, ~{N}-[2-ethyl-6-(4-methylpiperazin-1-yl)-3-oxidanylidene-2,7-diazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaen-9-yl]-2,4-bis(fluoranyl)benzenesulfonamide | Authors: | Zhang, C, Wang, C, Li, W, Zhang, Y, Xu, Y, Sun, L. | Deposit date: | 2022-01-12 | Release date: | 2022-08-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Design, synthesis, and anticancer evaluation of ammosamide B with pyrroloquinoline derivatives as novel BRD4 inhibitors. Bioorg.Chem., 127, 2022
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3GDZ
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![BU of 3gdz by Molmil](/molmil-images/mine/3gdz) | Crystal structure of arginyl-tRNA synthetase from Klebsiella pneumoniae subsp. pneumoniae | Descriptor: | 1,2-ETHANEDIOL, Arginyl-tRNA synthetase | Authors: | Chang, C, Wu, R, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-02-24 | Release date: | 2009-03-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of arginyl-tRNA synthetase from Klebsiella pneumoniae subsp. pneumoniae To be Published
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3K6R
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![BU of 3k6r by Molmil](/molmil-images/mine/3k6r) | CRYSTAL STRUCTURE OF putative transferase PH0793 FROM PYROCOCCUS HORIKOSHII | Descriptor: | putative transferase PH0793 | Authors: | Chang, C, Skarina, T, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-10-09 | Release date: | 2009-10-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Protein Ph0793 from Pyrococcus Horikoshii To be Published
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4DCI
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![BU of 4dci by Molmil](/molmil-images/mine/4dci) | Crystal structure of unknown funciton protein from Synechococcus sp. WH 8102 | Descriptor: | SULFATE ION, uncharacterized protein | Authors: | Chang, C, Marshall, N, Bearden, J, Palenik, B, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-01-17 | Release date: | 2012-02-01 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Crystal structure of unknown function protein from Synechococcus sp. WH 8102 To be Published
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3GL5
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![BU of 3gl5 by Molmil](/molmil-images/mine/3gl5) | Crystal structure of probable DsbA oxidoreductase SCO1869 from Streptomyces coelicolor | Descriptor: | ACETATE ION, Putative DsbA oxidoreductase SCO1869, SODIUM ION | Authors: | Chang, C, Xu, X, Cui, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-03-11 | Release date: | 2009-03-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of probable DsbA oxidoreductase SCO1869 from Streptomyces coelicolor To be Published
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3H9P
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![BU of 3h9p by Molmil](/molmil-images/mine/3h9p) | Crystal structure of putative triphosphoribosyl-dephospho-coA synthase from Archaeoglobus fulgidus | Descriptor: | CHLORIDE ION, GLYCEROL, TETRAETHYLENE GLYCOL, ... | Authors: | Chang, C, Wu, R, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-04-30 | Release date: | 2009-05-19 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of putative triphosphoribosyl-dephospho-coA synthase from Archaeoglobus fulgidus To be Published
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3K6C
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![BU of 3k6c by Molmil](/molmil-images/mine/3k6c) | Crystal structure of protein ne0167 from nitrosomonas europaea | Descriptor: | Uncharacterized protein NE0167 | Authors: | Chang, C, Evdokimova, E, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-10-08 | Release date: | 2009-10-27 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of Protein Ne0167 from Nitrosomonas Europaea To be Published
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2HA9
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4EY3
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![BU of 4ey3 by Molmil](/molmil-images/mine/4ey3) | Crystal structure of solute binding protein of ABC transporter in complex with p-hydroxybenzoic acid | Descriptor: | P-HYDROXYBENZOIC ACID, Twin-arginine translocation pathway signal | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J.Mol.Biol., 423, 2012
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2DHO
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![BU of 2dho by Molmil](/molmil-images/mine/2dho) | Crystal structure of human IPP isomerase I in space group P212121 | Descriptor: | CHLORIDE ION, Isopentenyl-diphosphate delta-isomerase 1, MANGANESE (II) ION, ... | Authors: | Zhang, C, Wei, Z, Gong, W. | Deposit date: | 2006-03-24 | Release date: | 2007-06-05 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structures of human IPP isomerase: new insights into the catalytic mechanism J.Mol.Biol., 366, 2007
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4J1R
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![BU of 4j1r by Molmil](/molmil-images/mine/4j1r) | Crystal Structure of GSK3b in complex with inhibitor 15R | Descriptor: | (2R)-2-(1H-indol-3-ylmethyl)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, Glycogen synthase kinase-3 beta, PHOSPHATE ION, ... | Authors: | Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-02-01 | Release date: | 2013-03-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor To be Published
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1N1F
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![BU of 1n1f by Molmil](/molmil-images/mine/1n1f) | Crystal Structure of Human Interleukin-19 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, interleukin-19 | Authors: | Chang, C, Magracheva, E, Kozlov, S, Fong, S, Tobin, G, Kotenko, S, Wlodawer, A, Zdanov, A. | Deposit date: | 2002-10-17 | Release date: | 2003-02-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of interleukin-19 defines a new subfamily of helical cytokines J.Biol.Chem., 278, 2003
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4OVK
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7KA0
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![BU of 7ka0 by Molmil](/molmil-images/mine/7ka0) | Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and phenylalanine | Descriptor: | ACETATE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Chang, C, Michalska, K, Jedrzejczak, R, Wower, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-09-29 | Release date: | 2021-05-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation. Nucleic Acids Res., 49, 2021
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7KAB
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![BU of 7kab by Molmil](/molmil-images/mine/7kab) | M. tuberculosis PheRS complex with cognate precursor tRNA and phenylalanine | Descriptor: | GLYCEROL, MAGNESIUM ION, PHENYLALANINE, ... | Authors: | Chang, C, Michalska, K, Jedrzejczak, R, Wower, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-09-30 | Release date: | 2021-05-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation. Nucleic Acids Res., 49, 2021
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4KVH
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![BU of 4kvh by Molmil](/molmil-images/mine/4kvh) | Crystal structure of ketosteroid isomerase fold protein Hmuk_0747 | Descriptor: | BROMIDE ION, CACODYLATE ION, FORMIC ACID, ... | Authors: | Chang, C, Holowicki, J, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2013-05-22 | Release date: | 2013-06-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Crystal structure of ketosteroid isomerase fold protein Hmuk_0747 To be Published
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4PE6
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![BU of 4pe6 by Molmil](/molmil-images/mine/4pe6) | Crystal structure of ABC transporter solute binding protein from Thermobispora bispora DSM 43833 | Descriptor: | (2R,3S)-2,3,4-trihydroxybutanoic acid, Putative ABC transporter | Authors: | Chang, C, Li, H, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-04-22 | Release date: | 2014-05-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal structure of ABC transporter solute binding protein from Thermobispora bispora DSM 43833 to be published
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4LMI
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![BU of 4lmi by Molmil](/molmil-images/mine/4lmi) | |
3VW7
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![BU of 3vw7 by Molmil](/molmil-images/mine/3vw7) | Crystal structure of human protease-activated receptor 1 (PAR1) bound with antagonist vorapaxar at 2.2 angstrom | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, Proteinase-activated receptor 1, ... | Authors: | Zhang, C, Srinivasan, Y, Arlow, D.H, Fung, J.J, Palmer, D, Zheng, Y, Green, H.F, Pandey, A, Dror, R.O, Shaw, D.E, Weis, W.I, Coughlin, S.R, Kobilka, B.K. | Deposit date: | 2012-08-07 | Release date: | 2012-12-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | High-resolution crystal structure of human protease-activated receptor 1 Nature, 492, 2012
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4PAG
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![BU of 4pag by Molmil](/molmil-images/mine/4pag) | ABC transporter solute binding protein from Sulfurospirillum deleyianum DSM 6946 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, HISTIDINE, ... | Authors: | Chang, C, Endres, M, Li, H, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-04-08 | Release date: | 2014-04-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Crystal structure of ABC transporter solute binding protein from Sulfurospirillum deleyianum DSM 6946 To Be Published
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4PDY
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![BU of 4pdy by Molmil](/molmil-images/mine/4pdy) | Crystal structure of aminoglycoside phosphotransferase from Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 | Descriptor: | Aminoglycoside phosphotransferase, HISTIDINE, THIOCYANATE ION | Authors: | Chang, C, Li, H, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-04-22 | Release date: | 2014-05-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal structure of aminoglycoside phosphotransferase from Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 To be published
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4MDY
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![BU of 4mdy by Molmil](/molmil-images/mine/4mdy) | |