4ODV
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4ODS
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4ODW
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![BU of 4odw by Molmil](/molmil-images/mine/4odw) | Unliganded Fab structure of lipid A-specific antibody A6 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, A6 Fab (IgG2b kappa) light chain, A6 Fab (IgG2b) heavy chain | Authors: | Haji-Ghassemi, O, Evans, S.V. | Deposit date: | 2014-01-10 | Release date: | 2015-06-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA. J.Biol.Chem., 290, 2015
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4ODT
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4ODU
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5DQJ
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![BU of 5dqj by Molmil](/molmil-images/mine/5dqj) | Structure of unliganded S55-5 Fab | Descriptor: | S55-5 Fab (IgG1 kappa) light chain, S55-5 Fab (IgG1) heavy chain | Authors: | Haji-Ghassemi, O, Evans, S.V. | Deposit date: | 2015-09-14 | Release date: | 2016-03-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Lipid A-antibody structures reveal a widely-utilized pocket specific for negatively charged groups derived from unrelated V-genes J.Biol.Chem., 2015
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5DQ9
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![BU of 5dq9 by Molmil](/molmil-images/mine/5dq9) | Structure of S55-3 Fab in complex with Lipid A | Descriptor: | 2-acetamido-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, MAb 44B1 light chain, ... | Authors: | Haji-Ghassemi, O, Evans, S.V. | Deposit date: | 2015-09-14 | Release date: | 2016-03-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Lipid A-antibody structures reveal a widely-utilized pocket specific for negatively charged groups derived from from unrelated V-genes J.Biol.Chem., 2015
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5DQD
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![BU of 5dqd by Molmil](/molmil-images/mine/5dqd) | Structure of S55-5 Fab in complex with lipid A carbohydrate backbone | Descriptor: | 2-acetamido-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, S55-5 Fab (IgG1 kappa) light chain, ... | Authors: | Haji-Ghassemi, O, Evans, S.V. | Deposit date: | 2015-09-14 | Release date: | 2016-03-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Lipid A-antibody structures reveal a widely-utilized pocket specific for negatively charged groups derived from unrelated V-genes J.Biol.Chem., 2015
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8DUJ
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8DRP
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8DTB
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8DVE
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4M7J
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![BU of 4m7j by Molmil](/molmil-images/mine/4m7j) | Crystal structure of S25-26 in complex with Kdo(2.8)Kdo(2.4)Kdo trisaccharide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, DI(HYDROXYETHYL)ETHER, ... | Authors: | Haji-Ghassemi, O, Evans, S.V, Muller-Loennies, S, Saldova, R, Muniyappa, M, Brade, L, Rudd, P.M, Harvey, D.J, Kosma, P, Brade, H. | Deposit date: | 2013-08-12 | Release date: | 2014-04-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan. J.Biol.Chem., 289, 2014
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4M93
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![BU of 4m93 by Molmil](/molmil-images/mine/4m93) | Unliganded 2 crystal structure of S25-26 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | Authors: | Haji-Ghassemi, O, Evans, S.V. | Deposit date: | 2013-08-14 | Release date: | 2014-04-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan. J.Biol.Chem., 289, 2014
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4M7Z
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![BU of 4m7z by Molmil](/molmil-images/mine/4m7z) | Unliganded 1 crystal structure of S25-26 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Haji-Ghassemi, O, Evans, S.V, Muller-Loennies, S, Saldova, R, Muniyappa, M, Brade, L, Rudd, P.M, Harvey, D.J, Kosma, P, Brade, H. | Deposit date: | 2013-08-12 | Release date: | 2014-04-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan. J.Biol.Chem., 289, 2014
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4MA1
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![BU of 4ma1 by Molmil](/molmil-images/mine/4ma1) | Unliganded 3 crystal structure of S25-26 Fab | Descriptor: | DI(HYDROXYETHYL)ETHER, POTASSIUM ION, S25-26 Fab (IgG1k) heavy chain, ... | Authors: | Haji-Ghassemi, O, Evans, S.V. | Deposit date: | 2013-08-15 | Release date: | 2014-04-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan. J.Biol.Chem., 289, 2014
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6C5J
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![BU of 6c5j by Molmil](/molmil-images/mine/6c5j) | S25-23 Fab in complex with Chlamydiaceae LPS (Crystal form 1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, IgG1 Fab Heavy Chain, ... | Authors: | Haji-Ghassemi, O, Evans, S.V. | Deposit date: | 2018-01-16 | Release date: | 2019-01-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude. Biochemistry, 58, 2019
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6C5K
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![BU of 6c5k by Molmil](/molmil-images/mine/6c5k) | S25-23 Fab in complex with Chlamydiaceae LPS (Crystal form 2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, IgG1 Fab Heavy Chain, ... | Authors: | Haji-Ghassemi, O, Evans, S.V. | Deposit date: | 2018-01-16 | Release date: | 2019-01-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude. Biochemistry, 58, 2019
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4Z8F
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4Z95
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7CF9
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![BU of 7cf9 by Molmil](/molmil-images/mine/7cf9) | Structure of RyR1 (Ca2+/CHL) | Descriptor: | 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | Authors: | Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. | Deposit date: | 2020-06-24 | Release date: | 2020-09-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural basis for diamide modulation of ryanodine receptor. Nat.Chem.Biol., 16, 2020
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6X36
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![BU of 6x36 by Molmil](/molmil-images/mine/6x36) | Pig R615C RyR1 in complex with CaM, EGTA (class 3, closed) | Descriptor: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor | Authors: | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | Deposit date: | 2020-05-21 | Release date: | 2021-01-13 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM. Nat Commun, 12, 2021
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6X32
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![BU of 6x32 by Molmil](/molmil-images/mine/6x32) | Wt pig RyR1 in complex with apoCaM, EGTA condition (class 1 and 2, closed) | Descriptor: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ... | Authors: | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | Deposit date: | 2020-05-21 | Release date: | 2021-01-13 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM. Nat Commun, 12, 2021
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6X35
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![BU of 6x35 by Molmil](/molmil-images/mine/6x35) | Pig R615C RyR1 in complex with CaM, EGTA (class 1, open) | Descriptor: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ... | Authors: | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | Deposit date: | 2020-05-21 | Release date: | 2021-01-13 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM. Nat Commun, 12, 2021
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6X33
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![BU of 6x33 by Molmil](/molmil-images/mine/6x33) | Wt pig RyR1 in complex with apoCaM, EGTA condition (class 3, open) | Descriptor: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ... | Authors: | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | Deposit date: | 2020-05-21 | Release date: | 2021-01-13 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM. Nat Commun, 12, 2021
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