4Z95

Fab structure of antibody S1-15 in complex with ssDNA DNA, 5'-5(dT)-p-3'

Summary for 4Z95

• Entry DOI: 10.2210/pdb4z95/pdb
• Related: 4Z8F
• Descriptor: S1-15 Fab (IgG2b) heavy chain, S1-15 Fab (IgG2b) light chain, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: antibody, fab, carbohydrate, lipid a, dna, immune system, immune system-dna complex, immune system/dna
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 48258.36

Authors

Haji-Ghassemi, O.,Evans, S.V. (deposition date: 2015-04-09, release date: 2015-06-24, Last modification date: 2023-09-27)

• Primary citation: Haji-Ghassemi, O.,Muller-Loennies, S.,Rodriguez, T.,Brade, L.,Kosma, P.,Brade, H.,Evans, S.V.; Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA.; J.Biol.Chem., 290:19629-19640, 2015; PubMed: 26085093; DOI: 10.1074/jbc.M115.657874

Experimental method

X-RAY DIFFRACTION (1.79 Å)