2O4C
 
 | | Crystal Structure of D-Erythronate-4-phosphate Dehydrogenase Complexed with NAD | | 分子名称: | Erythronate-4-phosphate dehydrogenase, GLYCEROL, L(+)-TARTARIC ACID, ... | | 著者 | Ha, J.Y, Lee, J.H, Kim, K.H, Kim, D.J, Lee, H.H, Kim, H.K, Yoon, H.J, Suh, S.W. | | 登録日 | 2006-12-04 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of d-Erythronate-4-phosphate Dehydrogenase Complexed with NAD
J.Mol.Biol., 366, 2007
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3Q3F
 | | Engineering Domain-Swapped Binding Interfaces by Mutually Exclusive Folding: Insertion of Ubiquitin into position 103 of Barnase | | 分子名称: | Ribonuclease/Ubiquitin chimeric protein, SULFATE ION | | 著者 | Ha, J.-H, Karchin, J.M, Walker-Kopp, N, Huang, L.-S, Berry, E.A, Loh, S.N. | | 登録日 | 2010-12-21 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.169 Å) | | 主引用文献 | Engineering domain-swapped binding interfaces by mutually exclusive folding.
J.Mol.Biol., 416, 2012
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3WR5
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4U6U
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7CM0
 | | Crystal structure of a glutaminyl cyclase in complex with NHV-1009 | | 分子名称: | 1-(cyclopentylmethyl)-1-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea, Glutaminyl-peptide cyclotransferase, ZINC ION | | 著者 | Lee, J.W, Song, J.Y, Jang, T.H, Ha, J.H. | | 登録日 | 2020-07-23 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design.
Eur.J.Med.Chem., 226, 2021
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1WOG
 | | Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily | | 分子名称: | HEXANE-1,6-DIAMINE, MANGANESE (II) ION, agmatinase | | 著者 | Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W. | | 登録日 | 2004-08-18 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
J.Biol.Chem., 279, 2004
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1WOH
 | | Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily | | 分子名称: | agmatinase | | 著者 | Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W. | | 登録日 | 2004-08-18 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
J.Biol.Chem., 279, 2004
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1WOI
 | | Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily | | 分子名称: | MANGANESE (II) ION, agmatinase | | 著者 | Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W. | | 登録日 | 2004-08-18 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
J.Biol.Chem., 279, 2004
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6A6P
 | | Crystal Structure of Peroxisome Proliferator-Activated Receptor Delta (PPARd)LBD in Complex with DN003316 | | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Peroxisome proliferator-activated receptor delta, heptyl beta-D-glucopyranoside, ... | | 著者 | Chin, J.W, Cho, S.J, Song, J.Y, Ha, J.H. | | 登録日 | 2018-06-29 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of Peroxisome Proliferator-Activated Receptor Delta (PPARd)LBD in Complex with DN003316
To Be Published
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1WOR
 | | Crystal Structure of T-protein of the Glycine Cleavage System | | 分子名称: | Aminomethyltransferase, DIHYDROLIPOIC ACID | | 著者 | Lee, H.H, Kim, D.J, Ahn, H.J, Ha, J.Y, Suh, S.W. | | 登録日 | 2004-08-24 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure of T-protein of the Glycine Cleavage System: Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia
J.Biol.Chem., 279, 2004
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1WOP
 | | Crystal Structure of T-protein of the Glycine Cleavage System | | 分子名称: | Aminomethyltransferase, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid | | 著者 | Lee, H.H, Kim, D.J, Ahn, H.J, Ha, J.Y, Suh, S.W. | | 登録日 | 2004-08-24 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of T-protein of the Glycine Cleavage System: Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia
J.Biol.Chem., 279, 2004
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6IJQ
 | | Solution structure of BCL-XL bound to P73-TAD peptide | | 分子名称: | Bcl-2-like protein 1,Bcl-2-like protein 1, Tumor protein p73 | | 著者 | Yoon, M.-K, Ha, J.-H, Lee, M.-S, Chi, S.-W. | | 登録日 | 2018-10-11 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-XL.
J. Biol. Chem., 293, 2018
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1WOS
 | | Crystal Structure of T-protein of the Glycine Cleavage System | | 分子名称: | Aminomethyltransferase | | 著者 | Lee, H.H, Kim, D.J, Ahn, H.J, Ha, J.Y, Suh, S.W. | | 登録日 | 2004-08-24 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Crystal Structure of T-protein of the Glycine Cleavage System: Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia
J.Biol.Chem., 279, 2004
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1WOO
 | | Crystal structure of T-protein of the Glycine Cleavage System | | 分子名称: | (6S)-5,6,7,8-TETRAHYDROFOLATE, Aminomethyltransferase | | 著者 | Lee, H.H, Kim, D.J, Ahn, H.J, Ha, J.Y, Suh, S.W. | | 登録日 | 2004-08-24 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of T-protein of the Glycine Cleavage System: Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia
J.Biol.Chem., 279, 2004
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2ARU
 | | Crystal structure of lipoate-protein ligase A bound with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Lipoate-protein ligase A, MAGNESIUM ION | | 著者 | Kim, D.J, Kim, K.H, Lee, H.H, Lee, S.J, Ha, J.Y, Yoon, H.J, Suh, S.W. | | 登録日 | 2005-08-22 | | 公開日 | 2005-10-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of lipoate-protein ligase A bound with the activated intermediate: insights into interaction with lipoyl domains
J.Biol.Chem., 280, 2005
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2ARS
 | | Crystal structure of lipoate-protein ligase A From Thermoplasma acidophilum | | 分子名称: | Lipoate-protein ligase A, MAGNESIUM ION | | 著者 | Kim, D.J, Kim, K.H, Lee, H.H, Lee, S.J, Ha, J.Y, Yoon, H.J, Suh, S.W. | | 登録日 | 2005-08-22 | | 公開日 | 2005-10-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Crystal structure of lipoate-protein ligase A bound with the activated intermediate: insights into interaction with lipoyl domains
J.Biol.Chem., 280, 2005
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2ART
 | | Crystal structure of lipoate-protein ligase A bound with lipoyl-AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, LIPOIC ACID, Lipoate-protein ligase A, ... | | 著者 | Kim, D.J, Kim, K.H, Lee, H.H, Lee, S.J, Ha, J.Y, Yoon, H.J, Suh, S.W. | | 登録日 | 2005-08-22 | | 公開日 | 2005-10-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of lipoate-protein ligase A bound with the activated intermediate: insights into interaction with lipoyl domains
J.Biol.Chem., 280, 2005
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5YA2
 | | Crystal structure of LsrK-HPr complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Autoinducer-2 kinase, HEXANE-1,6-DIOL, ... | | 著者 | Ryu, K.S, Ha, J.H. | | 登録日 | 2017-08-30 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Evidence of link between quorum sensing and sugar metabolism inEscherichia colirevealed via cocrystal structures of LsrK and HPr
Sci Adv, 4, 2018
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5YA1
 | | crystal structure of LsrK-HPr complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Autoinducer-2 kinase, HEXANE-1,6-DIOL, ... | | 著者 | Ryu, K.S, Ha, J.H. | | 登録日 | 2017-08-29 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Evidence of link between quorum sensing and sugar metabolism inEscherichia colirevealed via cocrystal structures of LsrK and HPr
Sci Adv, 4, 2018
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5YA0
 | | Crystal structure of LsrK and HPr complex | | 分子名称: | Autoinducer-2 kinase, HEXANE-1,6-DIOL, PHOSPHATE ION, ... | | 著者 | Ryu, K.S, Ha, J.H. | | 登録日 | 2017-08-29 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.997 Å) | | 主引用文献 | Evidence of link between quorum sensing and sugar metabolism inEscherichia colirevealed via cocrystal structures of LsrK and HPr
Sci Adv, 4, 2018
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2P1B
 | | Crystal structure of human nucleophosmin-core | | 分子名称: | Nucleophosmin | | 著者 | Lee, H.H, Kim, H.S, Kang, J.Y, Lee, B.I, Ha, J.Y, Yoon, H.J, Lim, S.O, Jung, G, Suh, S.W. | | 登録日 | 2007-03-03 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structure of human nucleophosmin-core reveals plasticity of the pentamer-pentamer interface
Proteins, 69, 2007
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6Q2F
 | | Structure of Rhamnosidase from Novosphingobium sp. PP1Y | | 分子名称: | Glycoside hydrolase family protein, SODIUM ION | | 著者 | Terry, B, Ha, J, Izzo, V, Sazinsky, M.H. | | 登録日 | 2019-08-07 | | 公開日 | 2019-11-27 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (2.20000076 Å) | | 主引用文献 | The crystal structure and insight into the substrate specificity of the alpha-L rhamnosidase RHA-P from Novosphingobium sp. PP1Y.
Arch.Biochem.Biophys., 679, 2019
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7ERA
 | | Crystal structure of human Biliverdin IX-beta reductase B with Olsalazine Sodium (OSS) | | 分子名称: | 5-[(E)-(3-carboxy-4-oxidanyl-phenyl)diazenyl]-2-oxidanyl-benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | | 登録日 | 2021-05-06 | | 公開日 | 2022-01-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
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7ER9
 | | Crystal structure of human Biliverdin IX-beta reductase B with Febuxostat (TEI) | | 分子名称: | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | | 登録日 | 2021-05-06 | | 公開日 | 2022-01-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
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7ERE
 | | Crystal structure of human Biliverdin IX-beta reductase B with Pyrantel Pamoate (PPA) | | 分子名称: | 4-[(3-carboxy-2-oxidanyl-naphthalen-1-yl)methyl]-3-oxidanyl-naphthalene-2-carboxylic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | | 登録日 | 2021-05-06 | | 公開日 | 2022-01-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
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