5YA2

Crystal structure of LsrK-HPr complex with ADP

Summary for 5YA2

DescriptorAutoinducer-2 kinase, Phosphocarrier protein HPr, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywordsquorum sensing, lsrk, hpr, complex, adp binding, structural protein
Biological sourceEscherichia coli (strain K12)
Total number of polymer chains4
Total molecular weight137628.9
Authors
Ryu, K.S.,Ha, J.H. (deposition date: 2017-08-30, release date: 2018-07-11)
Primary citation
Ha, J.H.,Hauk, P.,Cho, K.,Eo, Y.,Ma, X.,Stephens, K.,Cha, S.,Jeong, M.,Suh, J.Y.,Sintim, H.O.,Bentley, W.E.,Ryu, K.S.
Evidence of link between quorum sensing and sugar metabolism inEscherichia colirevealed via cocrystal structures of LsrK and HPr
Sci Adv, 4:eaar7063-eaar7063, 2018
PubMed: 29868643 (PDB entries with the same primary citation)
DOI: 10.1126/sciadv.aar7063
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.701 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25670.2%0.9%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5ya2
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Molmil generated image of 5ya2
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Molmil generated image of 5ya2
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More Biological unit images

Molmil generated image of 5ya2
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Molmil generated image of 5ya2
rotated about x axis by 90°
Molmil generated image of 5ya2
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (5ya2.pdb1.gz [188.4 KB])
Coordinate files for Biological unit (5ya2.pdb2.gz [187.08 KB])
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